| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the trihexyphenidyl-2158 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD2 | adducin 2 (beta) |
| AFF3 | AF4/FMR2 family, member 3 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| APOE | apolipoprotein E |
| APP | amyloid beta (A4) precursor protein |
| AR | androgen receptor |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARMC4 | armadillo repeat containing 4 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| B9D2 | B9 protein domain 2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DUSP4 | dual specificity phosphatase 4 |
| EFNB2 | ephrin-B2 |
| EIF1 | eukaryotic translation initiation factor 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM127B | family with sequence similarity 127, member B |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GPATCH4 | G patch domain containing 4 |
| GPR19 | G protein-coupled receptor 19 |
| GPR3 | G protein-coupled receptor 3 |
| GSN | gelsolin |
| GTPBP1 | GTP binding protein 1 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HSPA2 | heat shock 70kDa protein 2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IDS | iduronate 2-sulfatase |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IQCK | IQ motif containing K |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| IRF4 | interferon regulatory factor 4 |
| KLHL36 | kelch-like family member 36 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMF1 | lipase maturation factor 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MORN1 | MORN repeat containing 1 |
| MOS | v-mos Moloney murine sarcoma viral oncogene homolog |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| MTAP | methylthioadenosine phosphorylase |
| MVP | major vault protein |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NLRP1 | NLR family, pyrin domain containing 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PALLD | palladin, cytoskeletal associated protein |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICK1 | protein interacting with PRKCA 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PVR | poliovirus receptor |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RHOT2 | ras homolog family member T2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPS2 | ribosomal protein S2 |
| RPS28 | ribosomal protein S28 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RUNDC3B | RUN domain containing 3B |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLAMF8 | SLAM family member 8 |
| SMTN | smoothelin |
| SUSD4 | sushi domain containing 4 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TEX261 | testis expressed 261 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TMC7 | transmembrane channel-like 7 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRAF4 | TNF receptor-associated factor 4 |
| TYMP | thymidine phosphorylase |
| VWA1 | von Willebrand factor A domain containing 1 |
| XYLT2 | xylosyltransferase II |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF276 | zinc finger protein 276 |
| ZNF354A | zinc finger protein 354A |
| ZNF552 | zinc finger protein 552 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATG9A | autophagy related 9A |
| BNC2 | basonuclin 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CAPN15 | calpain 15 |
| CENPT | centromere protein T |
| CFP | complement factor properdin |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOC2A | double C2-like domains, alpha |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| EPHB6 | EPH receptor B6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EXOSC1 | exosome component 1 |
| FAM102A | family with sequence similarity 102, member A |
| FAM222B | family with sequence similarity 222, member B |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FBRS | fibrosin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FOSL1 | FOS-like antigen 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HDAC7 | histone deacetylase 7 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AM | histone cluster 1, H2am |
| HOXC8 | homeobox C8 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INO80D | INO80 complex subunit D |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1107 | KIAA1107 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC729164 | hCG1732469 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCC | mutated in colorectal cancers |
| MPZ | myelin protein zero |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PER3 | period circadian clock 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLTP | phospholipid transfer protein |
| PODNL1 | podocan-like 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF39 | ring finger protein 39 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SALL2 | spalt-like transcription factor 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERTAD3 | SERTA domain containing 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SNAI1 | snail family zinc finger 1 |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPATA20 | spermatogenesis associated 20 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SV2A | synaptic vesicle glycoprotein 2A |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM134 | transmembrane protein 134 |
| TMEM187 | transmembrane protein 187 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF16 | zinc finger protein 16 |
| ZNF749 | zinc finger protein 749 |
