| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the trihexyphenidyl-4015 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACAN | aggrecan |
| ACVR1B | activin A receptor, type IB |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AICDA | activation-induced cytidine deaminase |
| ANKRD12 | ankyrin repeat domain 12 |
| ATG10 | autophagy related 10 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BEND5 | BEN domain containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CADM1 | cell adhesion molecule 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC132 | coiled-coil domain containing 132 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD177 | CD177 molecule |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCA1 | chloride channel accessory 1 |
| CNTFR | ciliary neurotrophic factor receptor |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DCTN2 | dynactin 2 (p50) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| E2F5 | E2F transcription factor 5, p130-binding |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FCF1 | FCF1 rRNA-processing protein |
| FGF20 | fibroblast growth factor 20 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GPR15 | G protein-coupled receptor 15 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HCRTR1 | hypocretin (orexin) receptor 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HNF1B | HNF1 homeobox B |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL6 | interleukin 6 |
| IL6ST | interleukin 6 signal transducer |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KIF1C | kinesin family member 1C |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF6 | Kruppel-like factor 6 |
| KRT7 | keratin 7, type II |
| LAMA2 | laminin, alpha 2 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MID1 | midline 1 |
| MRAS | muscle RAS oncogene homolog |
| MST1L | macrophage stimulating 1-like |
| MYBPC3 | myosin binding protein C, cardiac |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYO1B | myosin IB |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NGLY1 | N-glycanase 1 |
| NMT2 | N-myristoyltransferase 2 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHOX2B | paired-like homeobox 2b |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKP4 | plakophilin 4 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RABGAP1 | RAB GTPase activating protein 1 |
| RBM4 | RNA binding motif protein 4 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPS14 | ribosomal protein S14 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STRN | striatin, calmodulin binding protein |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THBD | thrombomodulin |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIO | trio Rho guanine nucleotide exchange factor |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF236 | zinc finger protein 236 |
| ZNF573 | zinc finger protein 573 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| AXIN1 | axin 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CAPN15 | calpain 15 |
| CBX4 | chromobox homolog 4 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHMP6 | charged multivesicular body protein 6 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPNE7 | copine VII |
| CRLF1 | cytokine receptor-like factor 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DLL3 | delta-like 3 (Drosophila) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EXO5 | exonuclease 5 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF23 | fibroblast growth factor 23 |
| FGF3 | fibroblast growth factor 3 |
| FGL1 | fibrinogen-like 1 |
| FKBP5 | FK506 binding protein 5 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GPR85 | G protein-coupled receptor 85 |
| GPX4 | glutathione peroxidase 4 |
| HPR | haptoglobin-related protein |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFT54 | intraflagellar transport 54 |
| IPO8 | importin 8 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIRREL | kin of IRRE like (Drosophila) |
| LRRC61 | leucine rich repeat containing 61 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3B | mucin 3B, cell surface associated |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| NOTCH4 | notch 4 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PALMD | palmdelphin |
| PDE8B | phosphodiesterase 8B |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLM | polymerase (DNA directed), mu |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLAMF7 | SLAM family member 7 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SSBP3 | single stranded DNA binding protein 3 |
| SSTR4 | somatostatin receptor 4 |
| STK16 | serine/threonine kinase 16 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TH | tyrosine hydroxylase |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR13 | WD repeat domain 13 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF506 | zinc finger protein 506 |
| ZNF574 | zinc finger protein 574 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |
