| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the trihexyphenidyl-4133 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADM | adrenomedullin |
| AFF1 | AF4/FMR2 family, member 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ATF3 | activating transcription factor 3 |
| ATG13 | autophagy related 13 |
| ATN1 | atrophin 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BMP8A | bone morphogenetic protein 8a |
| C18ORF25 | chromosome 18 open reading frame 25 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARD9 | caspase recruitment domain family, member 9 |
| CAV3 | caveolin 3 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC14A | cell division cycle 14A |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN11 | claudin 11 |
| CLTA | clathrin, light chain A |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CTAGE5 | CTAGE family, member 5 |
| CTGF | connective tissue growth factor |
| DAPK3 | death-associated protein kinase 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DOCK10 | dedicator of cytokinesis 10 |
| EGR1 | early growth response 1 |
| FAM129A | family with sequence similarity 129, member A |
| FAM182B | family with sequence similarity 182, member B |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLOT1 | flotillin 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR85 | G protein-coupled receptor 85 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSTM5 | glutathione S-transferase mu 5 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOXA11 | homeobox A11 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGSF6 | immunoglobulin superfamily, member 6 |
| ING2 | inhibitor of growth family, member 2 |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLF2 | Kruppel-like factor 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MEF2D | myocyte enhancer factor 2D |
| METTL16 | methyltransferase like 16 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MUC3B | mucin 3B, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NEU3 | sialidase 3 (membrane sialidase) |
| NF1 | neurofibromin 1 |
| NTS | neurotensin |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PLSCR3 | phospholipid scramblase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POU2F2 | POU class 2 homeobox 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RORC | RAR-related orphan receptor C |
| SASH3 | SAM and SH3 domain containing 3 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC35G2 | solute carrier family 35, member G2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SSPN | sarcospan |
| SYNJ1 | synaptojanin 1 |
| SYT2 | synaptotagmin II |
| TEX14 | testis expressed 14 |
| TGFB2 | transforming growth factor, beta 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TOR4A | torsin family 4, member A |
| TRIM3 | tripartite motif containing 3 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF155 | zinc finger protein 155 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5AR1 | complement component 5a receptor 1 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CD53 | CD53 molecule |
| CEP131 | centrosomal protein 131kDa |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORT | cortistatin |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| EN2 | engrailed homeobox 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| EVPL | envoplakin |
| EXOC6B | exocyst complex component 6B |
| FAAH | fatty acid amide hydrolase |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FBXO31 | F-box protein 31 |
| GAMT | guanidinoacetate N-methyltransferase |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H4A | histone cluster 1, H4a |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IL11RA | interleukin 11 receptor, alpha |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0754 | KIAA0754 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL25 | kelch-like family member 25 |
| KRT83 | keratin 83, type II |
| LEFTY1 | left-right determination factor 1 |
| LTC4S | leukotriene C4 synthase |
| MAPK10 | mitogen-activated protein kinase 10 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MVD | mevalonate (diphospho) decarboxylase |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NAG18 | NAG18 mRNA |
| NDRG4 | NDRG family member 4 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPY4R | neuropeptide Y receptor Y4 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGP | phosphoglycolate phosphatase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMEL | premelanosome protein |
| POLH | polymerase (DNA directed), eta |
| PORCN | porcupine homolog (Drosophila) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PROL1 | proline rich, lacrimal 1 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB3D | RAB3D, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF122 | ring finger protein 122 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| S100A2 | S100 calcium binding protein A2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A6 | solute carrier family 16, member 6 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAB2 | stabilin 2 |
| TAOK1 | TAO kinase 1 |
| TEP1 | telomerase-associated protein 1 |
| TEX40 | testis expressed 40 |
| TLR5 | toll-like receptor 5 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| XYLT2 | xylosyltransferase II |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
