| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | tripartite motif containing 63, E3 ubiquitin protein ligase|This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 84676) |
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2 genes co-occuring with the biological term trim63 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
