| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the trimetazidine-1727 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| AGK | acylglycerol kinase |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| ATP5SL | ATP5S-like |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BRD3 | bromodomain containing 3 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CALU | calumenin |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG |
| CCDC64 | coiled-coil domain containing 64 |
| CD58 | CD58 molecule |
| CLEC4E | C-type lectin domain family 4, member E |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EGR4 | early growth response 4 |
| EHD1 | EH-domain containing 1 |
| EMC1 | ER membrane protein complex subunit 1 |
| FAM3A | family with sequence similarity 3, member A |
| FBLN1 | fibulin 1 |
| FCAR | Fc fragment of IgA receptor |
| FES | FES proto-oncogene, tyrosine kinase |
| FN1 | fibronectin 1 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GOLGA2 | golgin A2 |
| GPSM2 | G-protein signaling modulator 2 |
| GPSM3 | G-protein signaling modulator 3 |
| HDAC5 | histone deacetylase 5 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTRA2 | HtrA serine peptidase 2 |
| JMJD4 | jumonji domain containing 4 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF6 | Kruppel-like factor 6 |
| KLHL9 | kelch-like family member 9 |
| KPNB1 | karyopherin (importin) beta 1 |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGED2 | melanoma antigen family D2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| METRN | meteorin, glial cell differentiation regulator |
| MMP25 | matrix metallopeptidase 25 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MSH3 | mutS homolog 3 |
| MSRB2 | methionine sulfoxide reductase B2 |
| MYT1 | myelin transcription factor 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCAPH | non-SMC condensin I complex, subunit H |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PALM | paralemmin |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDH17 | protocadherin 17 |
| PCDHA9 | protocadherin alpha 9 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PMM2 | phosphomannomutase 2 |
| PPIEL | peptidylprolyl isomerase E-like pseudogene |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RANBP3 | RAN binding protein 3 |
| RNF123 | ring finger protein 123 |
| RNF17 | ring finger protein 17 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| SALL2 | spalt-like transcription factor 2 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCARB2 | scavenger receptor class B, member 2 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRT3 | sirtuin 3 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SMAD5 | SMAD family member 5 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPHK1 | sphingosine kinase 1 |
| SRRT | serrate, RNA effector molecule |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF1B | TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa |
| THAP4 | THAP domain containing 4 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| VAMP5 | vesicle-associated membrane protein 5 |
| WDR48 | WD repeat domain 48 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACO1 | aconitase 1, soluble |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| AHCTF1 | AT hook containing transcription factor 1 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| BBS1 | Bardet-Biedl syndrome 1 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| CCDC130 | coiled-coil domain containing 130 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLDN15 | claudin 15 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLSTN1 | calsyntenin 1 |
| CRY1 | cryptochrome circadian clock 1 |
| CS | citrate synthase |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DOK2 | docking protein 2, 56kDa |
| DPP3 | dipeptidyl-peptidase 3 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| ELP4 | elongator acetyltransferase complex subunit 4 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| EPX | eosinophil peroxidase |
| ERF | Ets2 repressor factor |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FAM136A | family with sequence similarity 136, member A |
| FAM222B | family with sequence similarity 222, member B |
| FBXO5 | F-box protein 5 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IFNA17 | interferon, alpha 17 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA0226 | KIAA0226 |
| KIFC1 | kinesin family member C1 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LEMD3 | LEM domain containing 3 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LYRM2 | LYR motif containing 2 |
| LYZ | lysozyme |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MBTD1 | mbt domain containing 1 |
| MED7 | mediator complex subunit 7 |
| MOCOS | molybdenum cofactor sulfurase |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MYO19 | myosin XIX |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| OARD1 | O-acyl-ADP-ribose deacylase 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC2 | origin recognition complex, subunit 2 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PRR11 | proline rich 11 |
| PSKH1 | protein serine kinase H1 |
| RFPL3 | ret finger protein-like 3 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| SDAD1 | SDA1 domain containing 1 |
| SIRT1 | sirtuin 1 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC25A38 | solute carrier family 25, member 38 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SNX10 | sorting nexin 10 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TRAPPC11 | trafficking protein particle complex 11 |
| TUBA4B | tubulin, alpha 4b |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBXN8 | UBX domain protein 8 |
| USP6 | ubiquitin specific peptidase 6 |
| VASP | vasodilator-stimulated phosphoprotein |
| WBP2 | WW domain binding protein 2 |
| WDR82 | WD repeat domain 82 |
| WRN | Werner syndrome, RecQ helicase-like |
| YEATS4 | YEATS domain containing 4 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF184 | zinc finger protein 184 |
| ZNF280D | zinc finger protein 280D |
| ZNF302 | zinc finger protein 302 |
| ZNF586 | zinc finger protein 586 |
