| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the trimetazidine-2876 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AFF2 | AF4/FMR2 family, member 2 |
| AIRE | autoimmune regulator |
| ANKRD55 | ankyrin repeat domain 55 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP11A | ATPase, class VI, type 11A |
| BCL2A1 | BCL2-related protein A1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTSF | cathepsin F |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| DFNA5 | deafness, autosomal dominant 5 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DVL2 | dishevelled segment polarity protein 2 |
| ELAC2 | elaC ribonuclease Z 2 |
| FAM174B | family with sequence similarity 174, member B |
| FAM182B | family with sequence similarity 182, member B |
| FGF6 | fibroblast growth factor 6 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HOXA11 | homeobox A11 |
| IFNA14 | interferon, alpha 14 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INHBE | inhibin, beta E |
| KCNC3 | potassium channel, voltage gated Shaw related subfamily C, member 3 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MXD4 | MAX dimerization protein 4 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NID1 | nidogen 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PARD3 | par-3 family cell polarity regulator |
| PAX5 | paired box 5 |
| PKP2 | plakophilin 2 |
| PLAC4 | placenta-specific 4 |
| PLCH1 | phospholipase C, eta 1 |
| PLLP | plasmolipin |
| PLXNB3 | plexin B3 |
| PML | promyelocytic leukemia |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRKCB | protein kinase C, beta |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PXN | paxillin |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1 | runt-related transcription factor 1 |
| SATB1 | SATB homeobox 1 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SFRP5 | secreted frizzled-related protein 5 |
| SFTPB | surfactant protein B |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIX2 | SIX homeobox 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STAT4 | signal transducer and activator of transcription 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| TCF3 | transcription factor 3 |
| TENM1 | teneurin transmembrane protein 1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TUBA3C | tubulin, alpha 3c |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VAMP5 | vesicle-associated membrane protein 5 |
| WASL | Wiskott-Aldrich syndrome-like |
| WDR1 | WD repeat domain 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALS2CL | ALS2 C-terminal like |
| APOD | apolipoprotein D |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATG2A | autophagy related 2A |
| AXIN1 | axin 1 |
| BIN3 | bridging integrator 3 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CBX8 | chromobox homolog 8 |
| CCDC130 | coiled-coil domain containing 130 |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ETV6 | ets variant 6 |
| FAM169A | family with sequence similarity 169, member A |
| FAM184A | family with sequence similarity 184, member A |
| FOSL1 | FOS-like antigen 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HS1BP3 | HCLS1 binding protein 3 |
| IPO8 | importin 8 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLHL26 | kelch-like family member 26 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMB3 | laminin, beta 3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEFV | Mediterranean fever |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPTX1 | neuronal pentraxin I |
| PADI2 | peptidyl arginine deiminase, type II |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHB3 | protocadherin beta 3 |
| PHF14 | PHD finger protein 14 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFXAP | regulatory factor X-associated protein |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RWDD3 | RWD domain containing 3 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIRT2 | sirtuin 2 |
| SIRT6 | sirtuin 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMAD7 | SMAD family member 7 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STAG3 | stromal antigen 3 |
| STBD1 | starch binding domain 1 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| STX1A | syntaxin 1A (brain) |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D2B | TBC1 domain family, member 2B |
| TMEM115 | transmembrane protein 115 |
| TMEM39B | transmembrane protein 39B |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBG2 | tubulin, gamma 2 |
| TYRP1 | tyrosinase-related protein 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR33 | WD repeat domain 33 |
| XYLT2 | xylosyltransferase II |
| YY2 | YY2 transcription factor |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF250 | zinc finger protein 250 |
| ZNF254 | zinc finger protein 254 |
| ZNF324 | zinc finger protein 324 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF571 | zinc finger protein 571 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF721 | zinc finger protein 721 |
