| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the trimetazidine-5060 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| AMH | anti-Mullerian hormone |
| APOC1 | apolipoprotein C-I |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASTN1 | astrotactin 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| BBC3 | BCL2 binding component 3 |
| CA9 | carbonic anhydrase IX |
| CAPN10 | calpain 10 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCNO | cyclin O |
| CD28 | CD28 molecule |
| CD58 | CD58 molecule |
| CDX1 | caudal type homeobox 1 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COBL | cordon-bleu WH2 repeat protein |
| COL1A1 | collagen, type I, alpha 1 |
| DAPK2 | death-associated protein kinase 2 |
| DCTN1 | dynactin 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DIO2 | deiodinase, iodothyronine, type II |
| FAM162A | family with sequence similarity 162, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FN1 | fibronectin 1 |
| GAB1 | GRB2-associated binding protein 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAL | galanin/GMAP prepropeptide |
| GATA3 | GATA binding protein 3 |
| GLB1L | galactosidase, beta 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HAMP | hepcidin antimicrobial peptide |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IL17RB | interleukin 17 receptor B |
| IL1R1 | interleukin 1 receptor, type I |
| ITGB4 | integrin, beta 4 |
| JAG1 | jagged 1 |
| KCNIP2 | Kv channel interacting protein 2 |
| KRT24 | keratin 24, type I |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC399491 | |
| LRRN3 | leucine rich repeat neuronal 3 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| METTL7A | methyltransferase like 7A |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP25 | matrix metallopeptidase 25 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NOP16 | NOP16 nucleolar protein |
| NTF3 | neurotrophin 3 |
| OMD | osteomodulin |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHF7 | PHD finger protein 7 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PML | promyelocytic leukemia |
| PNLIPRP2 | pancreatic lipase-related protein 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RAD51B | RAD51 paralog B |
| RAG2 | recombination activating gene 2 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RGS10 | regulator of G-protein signaling 10 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RXRB | retinoid X receptor, beta |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLA | Src-like-adaptor |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMO | smoothened, frizzled class receptor |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SP110 | SP110 nuclear body protein |
| SPATA1 | spermatogenesis associated 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULF1 | sulfatase 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TBX2 | T-box 2 |
| TBXA2R | thromboxane A2 receptor |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TPM1 | tropomyosin 1 (alpha) |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIM2 | tripartite motif containing 2 |
| XAB2 | XPA binding protein 2 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF222 | zinc finger protein 222 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AK5 | adenylate kinase 5 |
| AKTIP | AKT interacting protein |
| ATP13A2 | ATPase type 13A2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BEND5 | BEN domain containing 5 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD82 | CD82 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLIC3 | chloride intracellular channel 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| CSF1R | colony stimulating factor 1 receptor |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| DEAF1 | DEAF1 transcription factor |
| DNMBP | dynamin binding protein |
| DTWD1 | DTW domain containing 1 |
| EAF2 | ELL associated factor 2 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FA2H | fatty acid 2-hydroxylase |
| FANCE | Fanconi anemia, complementation group E |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPX2 | glutathione peroxidase 2 |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| H2AFJ | H2A histone family, member J |
| HIST1H2BO | histone cluster 1, H2bo |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXB9 | homeobox B9 |
| HOXC13 | homeobox C13 |
| IFT54 | intraflagellar transport 54 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL15RA | interleukin 15 receptor, alpha |
| IL4R | interleukin 4 receptor |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KIAA0355 | KIAA0355 |
| KLHL26 | kelch-like family member 26 |
| KRT34 | keratin 34, type I |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC100287590 | uncharacterized LOC100287590 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKX3-2 | NK3 homeobox 2 |
| NXPH4 | neurexophilin 4 |
| OSMR | oncostatin M receptor |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PER3 | period circadian clock 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLH | polymerase (DNA directed), eta |
| PRSS53 | protease, serine, 53 |
| PUS1 | pseudouridylate synthase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASA2 | RAS p21 protein activator 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGCC | regulator of cell cycle |
| SCAI | suppressor of cancer cell invasion |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPIDR | scaffolding protein involved in DNA repair |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAGLN | transgelin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| YY2 | YY2 transcription factor |
| ZNF254 | zinc finger protein 254 |
| ZNF358 | zinc finger protein 358 |
| ZNF41 | zinc finger protein 41 |
| ZNF76 | zinc finger protein 76 |
| ZNF93 | zinc finger protein 93 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
