| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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192 genes differentially expressed following the trimetazidine-5479 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| AIF1 | allograft inflammatory factor 1 |
| ANAPC13 | anaphase promoting complex subunit 13 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG10 | autophagy related 10 |
| ATXN3L | ataxin 3-like |
| BIN1 | bridging integrator 1 |
| BMP1 | bone morphogenetic protein 1 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC121 | coiled-coil domain containing 121 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD1E | CD1e molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD82 | CD82 molecule |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CYB5A | cytochrome b5 type A (microsomal) |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DEAF1 | DEAF1 transcription factor |
| DFNB31 | deafness, autosomal recessive 31 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DST | dystonin |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EVI2A | ecotropic viral integration site 2A |
| EXOC7 | exocyst complex component 7 |
| FAM65B | family with sequence similarity 65, member B |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGFR1OP | FGFR1 oncogene partner |
| FOXN2 | forkhead box N2 |
| FOXN3 | forkhead box N3 |
| FRZB | frizzled-related protein |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPATCH3 | G patch domain containing 3 |
| GPR157 | G protein-coupled receptor 157 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSAP | gamma-secretase activating protein |
| HBEGF | heparin-binding EGF-like growth factor |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-G | major histocompatibility complex, class I, G |
| HOXC5 | homeobox C5 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB4 | integrin, beta 4 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KRT6B | keratin 6B, type II |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LOC257152 | uncharacterized LOC257152 |
| LOC79999 | uncharacterized LOC79999 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MECOM | MDS1 and EVI1 complex locus |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MTMR8 | myotubularin related protein 8 |
| MZF1 | myeloid zinc finger 1 |
| NEK1 | NIMA-related kinase 1 |
| NLGN4X | neuroligin 4, X-linked |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 |
| OSMR | oncostatin M receptor |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDPN | podoplanin |
| PDZD2 | PDZ domain containing 2 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLAT | plasminogen activator, tissue |
| PLD2 | phospholipase D2 |
| PLK3 | polo-like kinase 3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRPF18 | pre-mRNA processing factor 18 |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SIRT3 | sirtuin 3 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| SYNJ1 | synaptojanin 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TNS1 | tensin 1 |
| TRIM10 | tripartite motif containing 10 |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| TTC28 | tetratricopeptide repeat domain 28 |
| ZNF287 | zinc finger protein 287 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDOC | aldolase C, fructose-bisphosphate |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| BAG4 | BCL2-associated athanogene 4 |
| BBC3 | BCL2 binding component 3 |
| BCL2L2 | BCL2-like 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5 | complement component 5 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC25 | coiled-coil domain containing 25 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPO | centromere protein O |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DSCAM | Down syndrome cell adhesion molecule |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EDC3 | enhancer of mRNA decapping 3 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXO31 | F-box protein 31 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3G | histone cluster 1, H3g |
| HOOK1 | hook microtubule-tethering protein 1 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RA | interleukin 17 receptor A |
| INO80D | INO80 complex subunit D |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JMJD1C | jumonji domain containing 1C |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF18A | kinesin family member 18A |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMA5 | laminin, alpha 5 |
| LMBR1L | limb development membrane protein 1-like |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MITF | microphthalmia-associated transcription factor |
| MOSPD3 | motile sperm domain containing 3 |
| MYL5 | myosin, light chain 5, regulatory |
| NES | nestin |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OTUD3 | OTU deubiquitinase 3 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PC | pyruvate carboxylase |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRKX | protein kinase, X-linked |
| PRSS22 | protease, serine, 22 |
| PYGB | phosphorylase, glycogen; brain |
| RAB5B | RAB5B, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF170 | ring finger protein 170 |
| RNF43 | ring finger protein 43 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TCTN1 | tectonic family member 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM53 | transmembrane protein 53 |
| TRABD | TraB domain containing |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| WDR18 | WD repeat domain 18 |
| XYLT2 | xylosyltransferase II |
| ZNF212 | zinc finger protein 212 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |
