trimethadione-4165 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trimethadione-4165 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AIM2 absent in melanoma 2
AK1 adenylate kinase 1
AKAP1 A kinase (PRKA) anchor protein 1
ARHGAP1 Rho GTPase activating protein 1
BEGAIN brain-enriched guanylate kinase-associated
BIN1 bridging integrator 1
BOK BCL2-related ovarian killer
C14ORF1 chromosome 14 open reading frame 1
C6 complement component 6
CALB1 calbindin 1, 28kDa
CD1A CD1a molecule
CD200 CD200 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDON cell adhesion associated, oncogene regulated
CLEC2B C-type lectin domain family 2, member B
CLTA clathrin, light chain A
COPE coatomer protein complex, subunit epsilon
CXCL13 chemokine (C-X-C motif) ligand 13
CYSLTR2 cysteinyl leukotriene receptor 2
DBT dihydrolipoamide branched chain transacylase E2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DIAPH2-AS1 DIAPH2 antisense RNA 1
DVL2 dishevelled segment polarity protein 2
ELL2 elongation factor, RNA polymerase II, 2
EVA1B eva-1 homolog B (C. elegans)
FABP3 fatty acid binding protein 3, muscle and heart
FBLN1 fibulin 1
FBXO40 F-box protein 40
FFAR3 free fatty acid receptor 3
FYB FYN binding protein
GBP1 guanylate binding protein 1, interferon-inducible
GGT1 gamma-glutamyltransferase 1
GHRHR growth hormone releasing hormone receptor
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRM8 glutamate receptor, metabotropic 8
HOXB5 homeobox B5
IL18RAP interleukin 18 receptor accessory protein
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK1 kallikrein 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LBP lipopolysaccharide binding protein
LIM2 lens intrinsic membrane protein 2, 19kDa
MALL mal, T-cell differentiation protein-like
MBD2 methyl-CpG binding domain protein 2
MC5R melanocortin 5 receptor
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MID1 midline 1
MNDA myeloid cell nuclear differentiation antigen
MYO9B myosin IXB
MYOZ1 myozenin 1
NCOR2 nuclear receptor corepressor 2
NOV nephroblastoma overexpressed
NPFFR1 neuropeptide FF receptor 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP88 nucleoporin 88kDa
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI3 peptidyl arginine deiminase, type III
PCDHGA1 protocadherin gamma subfamily A, 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHOX2B paired-like homeobox 2b
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDM14 PR domain containing 14
PRKG2 protein kinase, cGMP-dependent, type II
PTCH1 patched 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTK2B protein tyrosine kinase 2 beta
RGS4 regulator of G-protein signaling 4
SEMG2 semenogelin II
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC43A3 solute carrier family 43, member 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STATH statherin
STS steroid sulfatase (microsomal), isozyme S
SYN3 synapsin III
TAC3 tachykinin 3
TAGLN3 transgelin 3
TCF3 transcription factor 3
TEP1 telomerase-associated protein 1
THPO thrombopoietin
TRBC1 T cell receptor beta constant 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UGT8 UDP glycosyltransferase 8
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USH1C Usher syndrome 1C (autosomal recessive, severe)
UTS2 urotensin 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZER1 zyg-11 related, cell cycle regulator
ZNF155 zinc finger protein 155
ZNF304 zinc finger protein 304
ZNF334 zinc finger protein 334
ZNF384 zinc finger protein 384
ZNF702P zinc finger protein 702, pseudogene

decreased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AMPD1 adenosine monophosphate deaminase 1
AMPD3 adenosine monophosphate deaminase 3
ANKH ANKH inorganic pyrophosphate transport regulator
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
BAHCC1 BAH domain and coiled-coil containing 1
C11ORF21 chromosome 11 open reading frame 21
C14ORF79 chromosome 14 open reading frame 79
C1ORF54 chromosome 1 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CHST10 carbohydrate sulfotransferase 10
CLCF1 cardiotrophin-like cytokine factor 1
CLDN1 claudin 1
CRMP1 collapsin response mediator protein 1
CSF1R colony stimulating factor 1 receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
FAM155A family with sequence similarity 155, member A
FAM76A family with sequence similarity 76, member A
FBXO2 F-box protein 2
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FSCN3 fascin actin-bundling protein 3, testicular
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR176 G protein-coupled receptor 176
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HOXB2 homeobox B2
HOXC8 homeobox C8
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIF13B kinesin family member 13B
LATS1 large tumor suppressor kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOB3B MOB kinase activator 3B
NDOR1 NADPH dependent diflavin oxidoreductase 1
OSGIN1 oxidative stress induced growth inhibitor 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLSCR4 phospholipid scramblase 4
PMEL premelanosome protein
POLM polymerase (DNA directed), mu
PRKCE protein kinase C, epsilon
PTPRM protein tyrosine phosphatase, receptor type, M
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN1 Ras and Rab interactor 1
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGRIP1L RPGRIP1-like
RPH3A rabphilin 3A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNCAIP synuclein, alpha interacting protein
SOX12 SRY (sex determining region Y)-box 12
SPARCL1 SPARC-like 1 (hevin)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D19 TBC1 domain family, member 19
TBX19 T-box 19
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAIP TRAF interacting protein
TRIM68 tripartite motif containing 68
TRPM2 transient receptor potential cation channel, subfamily M, member 2
VASH2 vasohibin 2
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC11 zinc finger, DHHC-type containing 11
ZFHX4 zinc finger homeobox 4
ZNF137P zinc finger protein 137, pseudogene
ZNF286A zinc finger protein 286A
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF532 zinc finger protein 532