| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the trimethoprim-2307 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCY10 | adenylate cyclase 10 (soluble) |
| AIRE | autoimmune regulator |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL25 | chemokine (C-C motif) ligand 25 |
| CDC14A | cell division cycle 14A |
| CDK13 | cyclin-dependent kinase 13 |
| CDK6 | cyclin-dependent kinase 6 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CLEC4M | C-type lectin domain family 4, member M |
| CNTN5 | contactin 5 |
| CPNE7 | copine VII |
| CPQ | carboxypeptidase Q |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CST2 | cystatin SA |
| CTSZ | cathepsin Z |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EXOSC2 | exosome component 2 |
| FAM182B | family with sequence similarity 182, member B |
| FGF5 | fibroblast growth factor 5 |
| FLJ11292 | |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR143 | G protein-coupled receptor 143 |
| GPR45 | G protein-coupled receptor 45 |
| GRB10 | growth factor receptor-bound protein 10 |
| HNF1B | HNF1 homeobox B |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IL1RAP | interleukin 1 receptor accessory protein |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| LOXL3 | lysyl oxidase-like 3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MED25 | mediator complex subunit 25 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MID1 | midline 1 |
| MKRN3 | makorin ring finger protein 3 |
| MMP25 | matrix metallopeptidase 25 |
| MSX2 | msh homeobox 2 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYF5 | myogenic factor 5 |
| NIPAL3 | NIPA-like domain containing 3 |
| NPAS2 | neuronal PAS domain protein 2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OCLM | oculomedin |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OSBP2 | oxysterol binding protein 2 |
| PARVA | parvin, alpha |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHOX2A | paired-like homeobox 2a |
| PLAU | plasminogen activator, urokinase |
| PML | promyelocytic leukemia |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRKCE | protein kinase C, epsilon |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RASIP1 | Ras interacting protein 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RORA | RAR-related orphan receptor A |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTN2 | reticulon 2 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERHL2 | serine hydrolase-like 2 |
| SIRT4 | sirtuin 4 |
| SIX2 | SIX homeobox 2 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SRPK2 | SRSF protein kinase 2 |
| STAC | SH3 and cysteine rich domain |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
| TGFB2 | transforming growth factor, beta 2 |
| THAP9 | THAP domain containing 9 |
| THPO | thrombopoietin |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARRB1 | arrestin, beta 1 |
| ATP13A2 | ATPase type 13A2 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C5 | complement component 5 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK20 | cyclin-dependent kinase 20 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIC | capicua transcriptional repressor |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNN2 | calponin 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DMTN | dematin actin binding protein |
| DSCAM | Down syndrome cell adhesion molecule |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM114A2 | family with sequence similarity 114, member A2 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLTP | glycolipid transfer protein |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GSTM5 | glutathione S-transferase mu 5 |
| HIST1H1E | histone cluster 1, H1e |
| HPN | hepsin |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT22 | intraflagellar transport 22 |
| IFT81 | intraflagellar transport 81 |
| INCENP | inner centromere protein antigens 135/155kDa |
| JADE3 | jade family PHD finger 3 |
| KLHL25 | kelch-like family member 25 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAGEB2 | melanoma antigen family B2 |
| MAP1S | microtubule-associated protein 1S |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MEFV | Mediterranean fever |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYO19 | myosin XIX |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NLRX1 | NLR family member X1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCDHB13 | protocadherin beta 13 |
| PLA2G3 | phospholipase A2, group III |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RFTN1 | raftlin, lipid raft linker 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SIK1 | salt-inducible kinase 1 |
| SIX1 | SIX homeobox 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNAI2 | snail family zinc finger 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRPX | sushi-repeat containing protein, X-linked |
| STAB2 | stabilin 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEX40 | testis expressed 40 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM115 | transmembrane protein 115 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP18 | ubiquitin specific peptidase 18 |
| VASH2 | vasohibin 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF134 | zinc finger protein 134 |
| ZNF324 | zinc finger protein 324 |
| ZNF428 | zinc finger protein 428 |
| ZNF652 | zinc finger protein 652 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |