| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the trimethoprim-2345 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ANGPT1 | angiopoietin 1 |
| ANKRD26 | ankyrin repeat domain 26 |
| ATG10 | autophagy related 10 |
| AURKA | aurora kinase A |
| BCL2 | B-cell CLL/lymphoma 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CAPN15 | calpain 15 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP162 | centrosomal protein 162kDa |
| CEP250 | centrosomal protein 250kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHPF | chondroitin polymerizing factor |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CNTN1 | contactin 1 |
| COG5 | component of oligomeric golgi complex 5 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DAPK3 | death-associated protein kinase 3 |
| DCLK2 | doublecortin-like kinase 2 |
| DEPDC1 | DEP domain containing 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DTNA | dystrobrevin, alpha |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa |
| FAM3A | family with sequence similarity 3, member A |
| FBRS | fibrosin |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GK | glycerol kinase |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPR153 | G protein-coupled receptor 153 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL1RAP | interleukin 1 receptor accessory protein |
| IRX5 | iroquois homeobox 5 |
| KAT6B | K(lysine) acetyltransferase 6B |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KIAA0753 | KIAA0753 |
| KIF13B | kinesin family member 13B |
| KIF1B | kinesin family member 1B |
| LMTK1 | lemur tail kinase 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC257152 | uncharacterized LOC257152 |
| MED25 | mediator complex subunit 25 |
| MFAP3 | microfibrillar-associated protein 3 |
| NINJ2 | ninjurin 2 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PKP4 | plakophilin 4 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POLL | polymerase (DNA directed), lambda |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBM10 | RNA binding motif protein 10 |
| RBM19 | RNA binding motif protein 19 |
| RBM42 | RNA binding motif protein 42 |
| RIN3 | Ras and Rab interactor 3 |
| RYK | receptor-like tyrosine kinase |
| SCARB2 | scavenger receptor class B, member 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STC1 | stanniocalcin 1 |
| SYNJ2 | synaptojanin 2 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBX19 | T-box 19 |
| TBX2 | T-box 2 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM156 | transmembrane protein 156 |
| TMEM63A | transmembrane protein 63A |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| UNC119B | unc-119 homolog B (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VAX2 | ventral anterior homeobox 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZC3H11A | zinc finger CCCH-type containing 11A |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF287 | zinc finger protein 287 |
| ZNF337 | zinc finger protein 337 |
| ZNF606 | zinc finger protein 606 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACYP2 | acylphosphatase 2, muscle type |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ARRB2 | arrestin, beta 2 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC85C | coiled-coil domain containing 85C |
| CD151 | CD151 molecule (Raph blood group) |
| CDK3 | cyclin-dependent kinase 3 |
| CEP97 | centrosomal protein 97kDa |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CORO2A | coronin, actin binding protein, 2A |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSD | cathepsin D |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDN | dendrin |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DSPP | dentin sialophosphoprotein |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GAMT | guanidinoacetate N-methyltransferase |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR183 | G protein-coupled receptor 183 |
| GPR27 | G protein-coupled receptor 27 |
| HINFP | histone H4 transcription factor |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST2H2BE | histone cluster 2, H2be |
| ICK | intestinal cell (MAK-like) kinase |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| ILK | integrin-linked kinase |
| ITGB7 | integrin, beta 7 |
| JUNB | jun B proto-oncogene |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KLK5 | kallikrein-related peptidase 5 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MLPH | melanophilin |
| MPI | mannose phosphate isomerase |
| NIPAL2 | NIPA-like domain containing 2 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PRAF2 | PRA1 domain family, member 2 |
| PTX3 | pentraxin 3, long |
| RAB8B | RAB8B, member RAS oncogene family |
| RBKS | ribokinase |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFXAP | regulatory factor X-associated protein |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPE | ribulose-5-phosphate-3-epimerase |
| SCD5 | stearoyl-CoA desaturase 5 |
| SGMS1 | sphingomyelin synthase 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLFN12 | schlafen family member 12 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SSBP3 | single stranded DNA binding protein 3 |
| SUSD6 | sushi domain containing 6 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM115 | transmembrane protein 115 |
| TMEM159 | transmembrane protein 159 |
| TMEM177 | transmembrane protein 177 |
| TMEM212 | transmembrane protein 212 |
| TRIM5 | tripartite motif containing 5 |
| TSPAN5 | tetraspanin 5 |
| USP19 | ubiquitin specific peptidase 19 |
| VNN2 | vanin 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF211 | zinc finger protein 211 |
| ZNF227 | zinc finger protein 227 |
| ZNF250 | zinc finger protein 250 |
| ZNF350 | zinc finger protein 350 |
| ZNF611 | zinc finger protein 611 |
