| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the trimethoprim-3678 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADD2 | adducin 2 (beta) |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| AMH | anti-Mullerian hormone |
| ANXA10 | annexin A10 |
| APOL6 | apolipoprotein L, 6 |
| ASTN1 | astrotactin 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP5 | bone morphogenetic protein 5 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC57 | coiled-coil domain containing 57 |
| CD6 | CD6 molecule |
| CDC25C | cell division cycle 25C |
| CFAP70 | cilia and flagella associated protein 70 |
| CHI3L2 | chitinase 3-like 2 |
| CYTH3 | cytohesin 3 |
| DISC1 | disrupted in schizophrenia 1 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EMC3 | ER membrane protein complex subunit 3 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EXOSC2 | exosome component 2 |
| EXPH5 | exophilin 5 |
| FAM212B | family with sequence similarity 212, member B |
| FGF16 | fibroblast growth factor 16 |
| FLT1 | fms-related tyrosine kinase 1 |
| FRMPD4 | FERM and PDZ domain containing 4 |
| FRZB | frizzled-related protein |
| G6PC2 | glucose-6-phosphatase, catalytic, 2 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HCFC1 | host cell factor C1 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HPGDS | hematopoietic prostaglandin D synthase |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IFT140 | intraflagellar transport 140 |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| IL12B | interleukin 12B |
| IL32 | interleukin 32 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA0319L | KIAA0319-like |
| KLK13 | kallikrein-related peptidase 13 |
| LEPR | leptin receptor |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYRM9 | LYR motif containing 9 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MUC3B | mucin 3B, cell surface associated |
| MYO1F | myosin IF |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRG1 | neuregulin 1 |
| OTOR | otoraplin |
| PCDHB13 | protocadherin beta 13 |
| PIP | prolactin-induced protein |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB26 | RAB26, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RBM5 | RNA binding motif protein 5 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCN3B | sodium channel, voltage gated, type III beta subunit |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPANXC | SPANX family, member C |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| ST7L | suppression of tumorigenicity 7 like |
| STRN3 | striatin, calmodulin binding protein 3 |
| SYT2 | synaptotagmin II |
| T | T, brachyury homolog (mouse) |
| TMEM259 | transmembrane protein 259 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOX | thymocyte selection-associated high mobility group box |
| TRO | trophinin |
| XYLT1 | xylosyltransferase I |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF222 | zinc finger protein 222 |
| ZNF345 | zinc finger protein 345 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC71 | coiled-coil domain containing 71 |
| CD70 | CD70 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CES3 | carboxylesterase 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| COBL | cordon-bleu WH2 repeat protein |
| COL16A1 | collagen, type XVI, alpha 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CORO2A | coronin, actin binding protein, 2A |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| EDC3 | enhancer of mRNA decapping 3 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETNK2 | ethanolamine kinase 2 |
| FAM120C | family with sequence similarity 120C |
| GALK1 | galactokinase 1 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR3 | G protein-coupled receptor 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HDAC11 | histone deacetylase 11 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1T | histone cluster 1, H1t |
| IL17RB | interleukin 17 receptor B |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF13A | kinesin family member 13A |
| LIMD2 | LIM domain containing 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEFV | Mediterranean fever |
| MMP2 | matrix metallopeptidase 2 |
| MMP3 | matrix metallopeptidase 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| PC | pyruvate carboxylase |
| PDZK1 | PDZ domain containing 1 |
| PGP | phosphoglycolate phosphatase |
| PICK1 | protein interacting with PRKCA 1 |
| PODNL1 | podocan-like 1 |
| PTK6 | protein tyrosine kinase 6 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RNF122 | ring finger protein 122 |
| RNF2 | ring finger protein 2 |
| RPA4 | replication protein A4, 30kDa |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMO | smoothened, frizzled class receptor |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STAB2 | stabilin 2 |
| STK16 | serine/threonine kinase 16 |
| SYCP2 | synaptonemal complex protein 2 |
| SYT17 | synaptotagmin XVII |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TMEM40 | transmembrane protein 40 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| VASH1 | vasohibin 1 |
| WDR33 | WD repeat domain 33 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF141 | zinc finger protein 141 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |