| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the trimethoprim-4701 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK4 | aarF domain containing kinase 4 |
| ADM | adrenomedullin |
| AHNAK | AHNAK nucleoprotein |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AMACR | alpha-methylacyl-CoA racemase |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANGPT4 | angiopoietin 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARRB1 | arrestin, beta 1 |
| ARTN | artemin |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD34 | CD34 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CFAP45 | cilia and flagella associated protein 45 |
| CFAP69 | cilia and flagella associated protein 69 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| CREB1 | cAMP responsive element binding protein 1 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DIXDC1 | DIX domain containing 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EPS8L1 | EPS8-like 1 |
| FANCA | Fanconi anemia, complementation group A |
| FBXO21 | F-box protein 21 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FGFR3 | fibroblast growth factor receptor 3 |
| FMOD | fibromodulin |
| FUS | FUS RNA binding protein |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLRX3 | glutaredoxin 3 |
| GOLGA8B | golgin A8 family, member B |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HMG20B | high mobility group 20B |
| HRASLS2 | HRAS-like suppressor 2 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ING4 | inhibitor of growth family, member 4 |
| INHBA | inhibin, beta A |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNIP1 | Kv channel interacting protein 1 |
| KIAA0040 | KIAA0040 |
| LSP1 | lymphocyte-specific protein 1 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MED31 | mediator complex subunit 31 |
| NDRG2 | NDRG family member 2 |
| OTUD4 | OTU deubiquitinase 4 |
| PCDHA6 | protocadherin alpha 6 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PGR | progesterone receptor |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PKN1 | protein kinase N1 |
| PLAU | plasminogen activator, urokinase |
| PLD2 | phospholipase D2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNA1 | plexin A1 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKCE | protein kinase C, epsilon |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| QKI | QKI, KH domain containing, RNA binding |
| RAB6A | RAB6A, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| UBE3B | ubiquitin protein ligase E3B |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VGF | VGF nerve growth factor inducible |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZIC3 | Zic family member 3 |
| ZNF286A | zinc finger protein 286A |
| ZNF318 | zinc finger protein 318 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP11B | ATPase, class VI, type 11B |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CEL | carboxyl ester lipase |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORT | cortistatin |
| CSF1R | colony stimulating factor 1 receptor |
| DEAF1 | DEAF1 transcription factor |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHD3 | EH-domain containing 3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| FAM188A | family with sequence similarity 188, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO31 | F-box protein 31 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GLRA1 | glycine receptor, alpha 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HDAC11 | histone deacetylase 11 |
| IFT140 | intraflagellar transport 140 |
| IMPACT | impact RWD domain protein |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLK5 | kallikrein-related peptidase 5 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT31 | keratin 31, type I |
| KRT86 | keratin 86, type II |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MUC3A | mucin 3A, cell surface associated |
| MUC3B | mucin 3B, cell surface associated |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEUROD1 | neuronal differentiation 1 |
| NEUROD4 | neuronal differentiation 4 |
| NOL10 | nucleolar protein 10 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAT | plasminogen activator, tissue |
| PMEL | premelanosome protein |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS19 | regulator of G-protein signaling 19 |
| RIN1 | Ras and Rab interactor 1 |
| RPGRIP1L | RPGRIP1-like |
| SAA3P | serum amyloid A3 pseudogene |
| SAMD9 | sterile alpha motif domain containing 9 |
| SDC3 | syndecan 3 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SKI | SKI proto-oncogene |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TEP1 | telomerase-associated protein 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM212 | transmembrane protein 212 |
| TRAIP | TRAF interacting protein |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| UBQLN4 | ubiquilin 4 |
| UPK2 | uroplakin 2 |
| VASH1 | vasohibin 1 |
| VEGFB | vascular endothelial growth factor B |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF446 | zinc finger protein 446 |
| ZNF652 | zinc finger protein 652 |
| ZNF701 | zinc finger protein 701 |