| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the trimethoprim-7377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ASTN2 | astrotactin 2 |
| ATG2A | autophagy related 2A |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| AXIN1 | axin 1 |
| BTC | betacellulin |
| C9ORF40 | chromosome 9 open reading frame 40 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC42 | cell division cycle 42 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CUL7 | cullin 7 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DOK5 | docking protein 5 |
| DST | dystonin |
| DTNA | dystrobrevin, alpha |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| ELL | elongation factor RNA polymerase II |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPHB2 | EPH receptor B2 |
| ETV1 | ets variant 1 |
| FAM134B | family with sequence similarity 134, member B |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FUZ | fuzzy planar cell polarity protein |
| GK | glycerol kinase |
| GTPBP1 | GTP binding protein 1 |
| HHEX | hematopoietically expressed homeobox |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HTT | huntingtin |
| IL17RA | interleukin 17 receptor A |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA1644 | KIAA1644 |
| KLHL18 | kelch-like family member 18 |
| KLHL25 | kelch-like family member 25 |
| KRT6B | keratin 6B, type II |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LPIN1 | lipin 1 |
| MAP3K7CL | MAP3K7 C-terminal like |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MED16 | mediator complex subunit 16 |
| MR1 | major histocompatibility complex, class I-related |
| MRPL57 | mitochondrial ribosomal protein L57 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PGM5 | phosphoglucomutase 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXND1 | plexin D1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRKCA | protein kinase C, alpha |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RRAGB | Ras-related GTP binding B |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SETDB1 | SET domain, bifurcated 1 |
| SHROOM2 | shroom family member 2 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMC1A | structural maintenance of chromosomes 1A |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SRRT | serrate, RNA effector molecule |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SYT1 | synaptotagmin I |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAGLN3 | transgelin 3 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TM2D1 | TM2 domain containing 1 |
| TNIK | TRAF2 and NCK interacting kinase |
| TRAF4 | TNF receptor-associated factor 4 |
| TWISTNB | TWIST neighbor |
| UBOX5 | U-box domain containing 5 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF276 | zinc finger protein 276 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ALPK1 | alpha-kinase 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARMC6 | armadillo repeat containing 6 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CCDC106 | coiled-coil domain containing 106 |
| CCNO | cyclin O |
| CD70 | CD70 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH7 | cadherin 7, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CDON | cell adhesion associated, oncogene regulated |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC10A | C-type lectin domain family 10, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DENND3 | DENN/MADD domain containing 3 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ECM1 | extracellular matrix protein 1 |
| EN2 | engrailed homeobox 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| F8 | coagulation factor VIII, procoagulant component |
| FAM102A | family with sequence similarity 102, member A |
| FKBP5 | FK506 binding protein 5 |
| FOXA1 | forkhead box A1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GBX2 | gastrulation brain homeobox 2 |
| GRAMD4 | GRAM domain containing 4 |
| HAS2 | hyaluronan synthase 2 |
| HOMER2 | homer scaffolding protein 2 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IPO8 | importin 8 |
| KIAA0513 | KIAA0513 |
| KIF13B | kinesin family member 13B |
| KLF13 | Kruppel-like factor 13 |
| KRT34 | keratin 34, type I |
| KRT6A | keratin 6A, type II |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAGEF1 | melanoma antigen family F1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MED15 | mediator complex subunit 15 |
| METRN | meteorin, glial cell differentiation regulator |
| MLYCD | malonyl-CoA decarboxylase |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO9A | myosin IXA |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NINJ1 | ninjurin 1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLAC8 | placenta-specific 8 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB8B | RAB8B, member RAS oncogene family |
| RNF31 | ring finger protein 31 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SYNPO | synaptopodin |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMC5 | transmembrane channel-like 5 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TOR4A | torsin family 4, member A |
| TSC22D4 | TSC22 domain family, member 4 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VGF | VGF nerve growth factor inducible |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
