Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the trimethylcolchicinic acid-4787 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AKR1C4 | aldo-keto reductase family 1, member C4 |
APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
APOL2 | apolipoprotein L, 2 |
ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
ARL4C | ADP-ribosylation factor-like 4C |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
BMP8A | bone morphogenetic protein 8a |
BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
C21ORF2 | chromosome 21 open reading frame 2 |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CCL19 | chemokine (C-C motif) ligand 19 |
CCL8 | chemokine (C-C motif) ligand 8 |
CD300C | CD300c molecule |
CD70 | CD70 molecule |
CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
COL1A1 | collagen, type I, alpha 1 |
COMT | catechol-O-methyltransferase |
CSHL1 | chorionic somatomammotropin hormone-like 1 |
CTSF | cathepsin F |
CXCR2 | chemokine (C-X-C motif) receptor 2 |
DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
DOCK6 | dedicator of cytokinesis 6 |
EFNA3 | ephrin-A3 |
EGR1 | early growth response 1 |
EXOC5 | exocyst complex component 5 |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FCAR | Fc fragment of IgA receptor |
FER1L4 | fer-1-like family member 4, pseudogene (functional) |
FOXN3 | forkhead box N3 |
GDAP1 | ganglioside induced differentiation associated protein 1 |
GIMAP5 | GTPase, IMAP family member 5 |
GIPR | gastric inhibitory polypeptide receptor |
GLIPR1 | GLI pathogenesis-related 1 |
GPC1 | glypican 1 |
GUSBP3 | glucuronidase, beta pseudogene 3 |
GZMM | granzyme M (lymphocyte met-ase 1) |
HDAC7 | histone deacetylase 7 |
HIST1H1B | histone cluster 1, H1b |
HIST1H3J | histone cluster 1, H3j |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IFT27 | intraflagellar transport 27 |
IL21R | interleukin 21 receptor |
JAKMIP2 | janus kinase and microtubule interacting protein 2 |
KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
KDM4C | lysine (K)-specific demethylase 4C |
KIF25-AS1 | KIF25 antisense RNA 1 |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LRP6 | low density lipoprotein receptor-related protein 6 |
MASP2 | mannan-binding lectin serine peptidase 2 |
MBNL2 | muscleblind-like splicing regulator 2 |
NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
NFX1 | nuclear transcription factor, X-box binding 1 |
NOP14-AS1 | NOP14 antisense RNA 1 |
NUP188 | nucleoporin 188kDa |
NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
ORAI2 | ORAI calcium release-activated calcium modulator 2 |
PAX8 | paired box 8 |
PCDH1 | protocadherin 1 |
PDLIM3 | PDZ and LIM domain 3 |
PHF20 | PHD finger protein 20 |
PKLR | pyruvate kinase, liver and RBC |
PLCD1 | phospholipase C, delta 1 |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
PMFBP1 | polyamine modulated factor 1 binding protein 1 |
PNPLA2 | patatin-like phospholipase domain containing 2 |
PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
PRM1 | protamine 1 |
RAB11B | RAB11B, member RAS oncogene family |
RAD51 | RAD51 recombinase |
RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
RPS3A | ribosomal protein S3A |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SELPLG | selectin P ligand |
SFTPC | surfactant protein C |
SIGLEC8 | sialic acid binding Ig-like lectin 8 |
SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 |
SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
SORBS3 | sorbin and SH3 domain containing 3 |
SPEG | SPEG complex locus |
SSX1 | synovial sarcoma, X breakpoint 1 |
STX7 | syntaxin 7 |
SUGP1 | SURP and G patch domain containing 1 |
SYCE1L | synaptonemal complex central element protein 1-like |
SYNPO | synaptopodin |
TGFBR3 | transforming growth factor, beta receptor III |
THBS3 | thrombospondin 3 |
THOC5 | THO complex 5 |
THRB | thyroid hormone receptor, beta |
TUBA3C | tubulin, alpha 3c |
UBXN1 | UBX domain protein 1 |
UNC5B | unc-5 homolog B (C. elegans) |
VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
ZNF407 | zinc finger protein 407 |
ZNF442 | zinc finger protein 442 |
ZNF589 | zinc finger protein 589 |
Symbol | Name |
---|---|
AKAP12 | A kinase (PRKA) anchor protein 12 |
ANKRD36 | ankyrin repeat domain 36 |
BBS10 | Bardet-Biedl syndrome 10 |
C2ORF54 | chromosome 2 open reading frame 54 |
C7ORF43 | chromosome 7 open reading frame 43 |
CA11 | carbonic anhydrase XI |
CCDC88C | coiled-coil domain containing 88C |
CENPO | centromere protein O |
CRIP1 | cysteine-rich protein 1 (intestinal) |
DEAF1 | DEAF1 transcription factor |
DNAL4 | dynein, axonemal, light chain 4 |
DSCAM | Down syndrome cell adhesion molecule |
EDC4 | enhancer of mRNA decapping 4 |
ELP3 | elongator acetyltransferase complex subunit 3 |
ENO2 | enolase 2 (gamma, neuronal) |
ERF | Ets2 repressor factor |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
ETAA1 | Ewing tumor-associated antigen 1 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAM46C | family with sequence similarity 46, member C |
FBXL2 | F-box and leucine-rich repeat protein 2 |
FBXO46 | F-box protein 46 |
FEM1C | fem-1 homolog c (C. elegans) |
FGF23 | fibroblast growth factor 23 |
FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
GID4 | GID complex subunit 4 |
GSTA4 | glutathione S-transferase alpha 4 |
HDAC4 | histone deacetylase 4 |
HIST2H2AA3 | histone cluster 2, H2aa3 |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
HP1BP3 | heterochromatin protein 1, binding protein 3 |
HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
HSPA1L | heat shock 70kDa protein 1-like |
IFT140 | intraflagellar transport 140 |
IFT81 | intraflagellar transport 81 |
IL4R | interleukin 4 receptor |
IRF1 | interferon regulatory factor 1 |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
JMJD4 | jumonji domain containing 4 |
KAT2A | K(lysine) acetyltransferase 2A |
KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
L2HGDH | L-2-hydroxyglutarate dehydrogenase |
LIN7B | lin-7 homolog B (C. elegans) |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MBIP | MAP3K12 binding inhibitory protein 1 |
MED23 | mediator complex subunit 23 |
MEX3C | mex-3 RNA binding family member C |
MFSD11 | major facilitator superfamily domain containing 11 |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MUC3B | mucin 3B, cell surface associated |
MXD3 | MAX dimerization protein 3 |
MYL5 | myosin, light chain 5, regulatory |
NFE2L3 | nuclear factor, erythroid 2-like 3 |
NLRX1 | NLR family member X1 |
OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
PCDHB3 | protocadherin beta 3 |
PCTP | phosphatidylcholine transfer protein |
PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
PLA2G3 | phospholipase A2, group III |
PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
PLD3 | phospholipase D family, member 3 |
POMZP3 | POM121 and ZP3 fusion |
PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 |
PRKX | protein kinase, X-linked |
PTDSS2 | phosphatidylserine synthase 2 |
RAB3A | RAB3A, member RAS oncogene family |
RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
SDC3 | syndecan 3 |
SFMBT1 | Scm-like with four mbt domains 1 |
SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
STEAP4 | STEAP family member 4 |
TEAD3 | TEA domain family member 3 |
TLR5 | toll-like receptor 5 |
TMEM184C | transmembrane protein 184C |
TMEM53 | transmembrane protein 53 |
TRAPPC11 | trafficking protein particle complex 11 |
TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
TSC1 | tuberous sclerosis 1 |
TTBK2 | tau tubulin kinase 2 |
TWF2 | twinfilin actin binding protein 2 |
UNC119 | unc-119 homolog (C. elegans) |
URM1 | ubiquitin related modifier 1 |
USP20 | ubiquitin specific peptidase 20 |
VGF | VGF nerve growth factor inducible |
VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
VWA1 | von Willebrand factor A domain containing 1 |
ZNF212 | zinc finger protein 212 |
ZNF219 | zinc finger protein 219 |
ZNF280D | zinc finger protein 280D |
ZNF35 | zinc finger protein 35 |
ZNF623 | zinc finger protein 623 |
ZNF747 | zinc finger protein 747 |
ZNF767P | zinc finger family member 767, pseudogene |