trimethylcolchicinic acid-4787 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the trimethylcolchicinic acid-4787 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C4 aldo-keto reductase family 1, member C4
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOL2 apolipoprotein L, 2
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL4C ADP-ribosylation factor-like 4C
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BMP8A bone morphogenetic protein 8a
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C21ORF2 chromosome 21 open reading frame 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL19 chemokine (C-C motif) ligand 19
CCL8 chemokine (C-C motif) ligand 8
CD300C CD300c molecule
CD70 CD70 molecule
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CSHL1 chorionic somatomammotropin hormone-like 1
CTSF cathepsin F
CXCR2 chemokine (C-X-C motif) receptor 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOCK6 dedicator of cytokinesis 6
EFNA3 ephrin-A3
EGR1 early growth response 1
EXOC5 exocyst complex component 5
FBXL7 F-box and leucine-rich repeat protein 7
FCAR Fc fragment of IgA receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
FOXN3 forkhead box N3
GDAP1 ganglioside induced differentiation associated protein 1
GIMAP5 GTPase, IMAP family member 5
GIPR gastric inhibitory polypeptide receptor
GLIPR1 GLI pathogenesis-related 1
GPC1 glypican 1
GUSBP3 glucuronidase, beta pseudogene 3
GZMM granzyme M (lymphocyte met-ase 1)
HDAC7 histone deacetylase 7
HIST1H1B histone cluster 1, H1b
HIST1H3J histone cluster 1, H3j
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFT27 intraflagellar transport 27
IL21R interleukin 21 receptor
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM4C lysine (K)-specific demethylase 4C
KIF25-AS1 KIF25 antisense RNA 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRP6 low density lipoprotein receptor-related protein 6
MASP2 mannan-binding lectin serine peptidase 2
MBNL2 muscleblind-like splicing regulator 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NFX1 nuclear transcription factor, X-box binding 1
NOP14-AS1 NOP14 antisense RNA 1
NUP188 nucleoporin 188kDa
NXPE3 neurexophilin and PC-esterase domain family, member 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ORAI2 ORAI calcium release-activated calcium modulator 2
PAX8 paired box 8
PCDH1 protocadherin 1
PDLIM3 PDZ and LIM domain 3
PHF20 PHD finger protein 20
PKLR pyruvate kinase, liver and RBC
PLCD1 phospholipase C, delta 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PNPLA2 patatin-like phospholipase domain containing 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRM1 protamine 1
RAB11B RAB11B, member RAS oncogene family
RAD51 RAD51 recombinase
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS3A ribosomal protein S3A
SCGB2A1 secretoglobin, family 2A, member 1
SELPLG selectin P ligand
SFTPC surfactant protein C
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SORBS3 sorbin and SH3 domain containing 3
SPEG SPEG complex locus
SSX1 synovial sarcoma, X breakpoint 1
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SYCE1L synaptonemal complex central element protein 1-like
SYNPO synaptopodin
TGFBR3 transforming growth factor, beta receptor III
THBS3 thrombospondin 3
THOC5 THO complex 5
THRB thyroid hormone receptor, beta
TUBA3C tubulin, alpha 3c
UBXN1 UBX domain protein 1
UNC5B unc-5 homolog B (C. elegans)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZNF407 zinc finger protein 407
ZNF442 zinc finger protein 442
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD36 ankyrin repeat domain 36
BBS10 Bardet-Biedl syndrome 10
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CA11 carbonic anhydrase XI
CCDC88C coiled-coil domain containing 88C
CENPO centromere protein O
CRIP1 cysteine-rich protein 1 (intestinal)
DEAF1 DEAF1 transcription factor
DNAL4 dynein, axonemal, light chain 4
DSCAM Down syndrome cell adhesion molecule
EDC4 enhancer of mRNA decapping 4
ELP3 elongator acetyltransferase complex subunit 3
ENO2 enolase 2 (gamma, neuronal)
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46C family with sequence similarity 46, member C
FBXL2 F-box and leucine-rich repeat protein 2
FBXO46 F-box protein 46
FEM1C fem-1 homolog c (C. elegans)
FGF23 fibroblast growth factor 23
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GID4 GID complex subunit 4
GSTA4 glutathione S-transferase alpha 4
HDAC4 histone deacetylase 4
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPA1L heat shock 70kDa protein 1-like
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
IL4R interleukin 4 receptor
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KAT2A K(lysine) acetyltransferase 2A
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
L2HGDH L-2-hydroxyglutarate dehydrogenase
LIN7B lin-7 homolog B (C. elegans)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAST3 microtubule associated serine/threonine kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MED23 mediator complex subunit 23
MEX3C mex-3 RNA binding family member C
MFSD11 major facilitator superfamily domain containing 11
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUC3B mucin 3B, cell surface associated
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDHB3 protocadherin beta 3
PCTP phosphatidylcholine transfer protein
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD3 phospholipase D family, member 3
POMZP3 POM121 and ZP3 fusion
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRKX protein kinase, X-linked
PTDSS2 phosphatidylserine synthase 2
RAB3A RAB3A, member RAS oncogene family
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SDC3 syndecan 3
SFMBT1 Scm-like with four mbt domains 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
STEAP4 STEAP family member 4
TEAD3 TEA domain family member 3
TLR5 toll-like receptor 5
TMEM184C transmembrane protein 184C
TMEM53 transmembrane protein 53
TRAPPC11 trafficking protein particle complex 11
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC1 tuberous sclerosis 1
TTBK2 tau tubulin kinase 2
TWF2 twinfilin actin binding protein 2
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
ZNF212 zinc finger protein 212
ZNF219 zinc finger protein 219
ZNF280D zinc finger protein 280D
ZNF35 zinc finger protein 35
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene