trimipramine-3342 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the trimipramine-3342 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
ARSD arylsulfatase D
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BCO1 beta-carotene oxygenase 1
BMP1 bone morphogenetic protein 1
BTNL3 butyrophilin-like 3
C6 complement component 6
CD248 CD248 molecule, endosialin
CDHR1 cadherin-related family member 1
CDK6 cyclin-dependent kinase 6
CHN2 chimerin 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CREBBP CREB binding protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYTH4 cytohesin 4
DENND5B DENN/MADD domain containing 5B
DLC1 DLC1 Rho GTPase activating protein
DMXL2 Dmx-like 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD1 dopamine receptor D1
ECE1 endothelin converting enzyme 1
ELL elongation factor RNA polymerase II
ELSPBP1 epididymal sperm binding protein 1
ERC2-IT1 ERC2 intronic transcript 1
ESR1 estrogen receptor 1
ETV4 ets variant 4
EXOSC1 exosome component 1
FAM182B family with sequence similarity 182, member B
FHL1 four and a half LIM domains 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAS7 growth arrest-specific 7
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPR161 G protein-coupled receptor 161
GPR3 G protein-coupled receptor 3
GRM1 glutamate receptor, metabotropic 1
GVINP1 GTPase, very large interferon inducible pseudogene 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HPX hemopexin
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICOSLG inducible T-cell co-stimulator ligand
IDI2-AS1 IDI2 antisense RNA 1
IGFBP5 insulin-like growth factor binding protein 5
IL12RB1 interleukin 12 receptor, beta 1
IL18 interleukin 18
INHBA inhibin, beta A
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNIP2 Kv channel interacting protein 2
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1C kinesin family member 1C
KLK13 kallikrein-related peptidase 13
LAMA2 laminin, alpha 2
LAMC2 laminin, gamma 2
LOC100131510 uncharacterized LOC100131510
LOC157562 uncharacterized LOC157562
MAGEA5 melanoma antigen family A5
MAP1A microtubule-associated protein 1A
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIER2 mesoderm induction early response 1, family member 2
MUC3B mucin 3B, cell surface associated
N4BP2L1 NEDD4 binding protein 2-like 1
NEUROD4 neuronal differentiation 4
NF1 neurofibromin 1
NOX1 NADPH oxidase 1
NPC1 Niemann-Pick disease, type C1
NRG2 neuregulin 2
OLFML2A olfactomedin-like 2A
PDE4B phosphodiesterase 4B, cAMP-specific
PLTP phospholipid transfer protein
PRLR prolactin receptor
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTHLH parathyroid hormone-like hormone
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RGS12 regulator of G-protein signaling 12
RUNX1 runt-related transcription factor 1
SAMD9 sterile alpha motif domain containing 9
SCN11A sodium channel, voltage gated, type XI alpha subunit
SLC12A8 solute carrier family 12, member 8
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPAG8 sperm associated antigen 8
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSX3 synovial sarcoma, X breakpoint 3
STATH statherin
TAGLN3 transgelin 3
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIMP3 TIMP metallopeptidase inhibitor 3
TUBA3C tubulin, alpha 3c
UHRF1BP1L UHRF1 binding protein 1-like
ULBP1 UL16 binding protein 1
VAV2 vav 2 guanine nucleotide exchange factor
WIPF1 WAS/WASL interacting protein family, member 1
WIZ widely interspaced zinc finger motifs
YPEL1 yippee-like 1 (Drosophila)
ZC3H7B zinc finger CCCH-type containing 7B
ZMAT4 zinc finger, matrin-type 4
ZNF280A zinc finger protein 280A
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
ADAP2 ArfGAP with dual PH domains 2
AGO1 argonaute RISC catalytic component 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ASIC3 acid sensing (proton gated) ion channel 3
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C1ORF159 chromosome 1 open reading frame 159
C2ORF27A chromosome 2 open reading frame 27A
C2ORF54 chromosome 2 open reading frame 54
CAPRIN2 caprin family member 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC69 coiled-coil domain containing 69
CD82 CD82 molecule
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CRY2 cryptochrome circadian clock 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DDIT3 DNA-damage-inducible transcript 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM204A family with sequence similarity 204, member A
FAM46C family with sequence similarity 46, member C
FER fer (fps/fes related) tyrosine kinase
GALK1 galactokinase 1
GMPR guanosine monophosphate reductase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HDAC7 histone deacetylase 7
HIST1H2AL histone cluster 1, H2al
HOXA4 homeobox A4
HOXC5 homeobox C5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
IPO8 importin 8
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KIF13A kinesin family member 13A
KLK5 kallikrein-related peptidase 5
LIN7B lin-7 homolog B (C. elegans)
MANSC1 MANSC domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MFSD12 major facilitator superfamily domain containing 12
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MVP major vault protein
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NPTX1 neuronal pentraxin I
NRGN neurogranin (protein kinase C substrate, RC3)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARD6A par-6 family cell polarity regulator alpha
PGBD5 piggyBac transposable element derived 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POM121 POM121 transmembrane nucleoporin
PRKX protein kinase, X-linked
PROS1 protein S (alpha)
RAB3D RAB3D, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
ROM1 retinal outer segment membrane protein 1
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SKI SKI proto-oncogene
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC46A3 solute carrier family 46, member 3
SPTBN2 spectrin, beta, non-erythrocytic 2
STBD1 starch binding domain 1
STON1 stonin 1
SYBU syntabulin (syntaxin-interacting)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D2 TBC1 domain family, member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRAIP TRAF interacting protein
TTC33 tetratricopeptide repeat domain 33
VIPR1 vasoactive intestinal peptide receptor 1
WDR25 WD repeat domain 25
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF16 zinc finger protein 16
ZNF365 zinc finger protein 365
ZNRD1-AS1 ZNRD1 antisense RNA 1