| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the trimipramine-4163 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACACB | acetyl-CoA carboxylase beta |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| ATF3 | activating transcription factor 3 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CD83 | CD83 molecule |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EPOR | erythropoietin receptor |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM46C | family with sequence similarity 46, member C |
| FGF18 | fibroblast growth factor 18 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLRX | glutaredoxin (thioltransferase) |
| GP6 | glycoprotein VI (platelet) |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HIST1H3B | histone cluster 1, H3b |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXA11 | homeobox A11 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KIF21B | kinesin family member 21B |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| LAMB4 | laminin, beta 4 |
| LGSN | lengsin, lens protein with glutamine synthetase domain |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MC5R | melanocortin 5 receptor |
| MCAM | melanoma cell adhesion molecule |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NID1 | nidogen 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PALM | paralemmin |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PER1 | period circadian clock 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| RALYL | RALY RNA binding protein-like |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RORA | RAR-related orphan receptor A |
| RUFY3 | RUN and FYVE domain containing 3 |
| RUNX1 | runt-related transcription factor 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SH2D2A | SH2 domain containing 2A |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| TAOK2 | TAO kinase 2 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX14 | testis expressed 14 |
| TMEM206 | transmembrane protein 206 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM15 | tripartite motif containing 15 |
| ZIC3 | Zic family member 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF407 | zinc finger protein 407 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ANKRD36 | ankyrin repeat domain 36 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLGN | calmegin |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSTN2 | calsyntenin 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DBR1 | debranching RNA lariats 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DOK5 | docking protein 5 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM155A | family with sequence similarity 155, member A |
| FAM155B | family with sequence similarity 155, member B |
| FBXO2 | F-box protein 2 |
| FBXO31 | F-box protein 31 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLI3 | GLI family zinc finger 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD1C | GRAM domain containing 1C |
| GRPR | gastrin-releasing peptide receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H1E | histone cluster 1, H1e |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0319L | KIAA0319-like |
| LHX1 | LIM homeobox 1 |
| LIAS | lipoic acid synthetase |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MBTD1 | mbt domain containing 1 |
| MMP2 | matrix metallopeptidase 2 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO1F | myosin IF |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NLRX1 | NLR family member X1 |
| NME5 | NME/NM23 family member 5 |
| NPTX1 | neuronal pentraxin I |
| OTUD3 | OTU deubiquitinase 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB13 | protocadherin beta 13 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRKCE | protein kinase C, epsilon |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCRN3 | secernin 3 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIRAL2 | SIR2 antiphage like 2 |
| SMAD5 | SMAD family member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPIN1 | spindlin 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UPK3B | uroplakin 3B |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VASH2 | vasohibin 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR76 | WD repeat domain 76 |
| WWC2 | WW and C2 domain containing 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| ZW10 | zw10 kinetochore protein |
