trioxysalen-6078 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trioxysalen-6078 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRA2 adhesion G protein-coupled receptor A2
ASIC2 acid sensing (proton gated) ion channel 2
ATXN7L1 ataxin 7-like 1
C10ORF10 chromosome 10 open reading frame 10
C1ORF54 chromosome 1 open reading frame 54
C4BPA complement component 4 binding protein, alpha
CAPN2 calpain 2, (m/II) large subunit
CCDC87 coiled-coil domain containing 87
CD84 CD84 molecule
CDK18 cyclin-dependent kinase 18
CDRT1 CMT1A duplicated region transcript 1
CELF3 CUGBP, Elav-like family member 3
CEP41 centrosomal protein 41kDa
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCA3P chloride channel accessory 3, pseudogene
CNOT2 CCR4-NOT transcription complex, subunit 2
COL13A1 collagen, type XIII, alpha 1
COMT catechol-O-methyltransferase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTSF cathepsin F
CTSZ cathepsin Z
CYBB cytochrome b-245, beta polypeptide
DOK5 docking protein 5
EDN1 endothelin 1
EMID1 EMI domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERP44 endoplasmic reticulum protein 44
F11 coagulation factor XI
FBXO2 F-box protein 2
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GLB1L galactosidase, beta 1-like
GM2A GM2 ganglioside activator
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRIK5 glutamate receptor, ionotropic, kainate 5
HIC2 hypermethylated in cancer 2
HRG histidine-rich glycoprotein
HYAL1 hyaluronoglucosaminidase 1
ICAM1 intercellular adhesion molecule 1
IFT27 intraflagellar transport 27
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
LDHB lactate dehydrogenase B
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC157562 uncharacterized LOC157562
LRRC17 leucine rich repeat containing 17
MAPK8 mitogen-activated protein kinase 8
MBD2 methyl-CpG binding domain protein 2
MLANA melan-A
MLXIPL MLX interacting protein-like
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
PCDHB11 protocadherin beta 11
PDE4C phosphodiesterase 4C, cAMP-specific
PKNOX2 PBX/knotted 1 homeobox 2
PLCH1 phospholipase C, eta 1
PLK3 polo-like kinase 3
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PNMT phenylethanolamine N-methyltransferase
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP5C protein phosphatase 5, catalytic subunit
PQBP1 polyglutamine binding protein 1
PRAMEF11 PRAME family member 11
PSD3 pleckstrin and Sec7 domain containing 3
PSG11 pregnancy specific beta-1-glycoprotein 11
PTPRJ protein tyrosine phosphatase, receptor type, J
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SH2D2A SH2 domain containing 2A
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIPA1 signal-induced proliferation-associated 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC43A3 solute carrier family 43, member 3
SLC45A2 solute carrier family 45, member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD1 SMAD family member 1
SNTA1 syntrophin, alpha 1
SRCAP Snf2-related CREBBP activator protein
STAT4 signal transducer and activator of transcription 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYNGR4 synaptogyrin 4
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAPBP TAP binding protein (tapasin)
TGM2 transglutaminase 2
TIMP3 TIMP metallopeptidase inhibitor 3
TOP3B topoisomerase (DNA) III beta
TREM2 triggering receptor expressed on myeloid cells 2
TTC38 tetratricopeptide repeat domain 38
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZNF154 zinc finger protein 154

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
B9D2 B9 protein domain 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTF3P12 basic transcription factor 3 pseudogene 12
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK4 dedicator of cytokinesis 4
DSPP dentin sialophosphoprotein
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HDAC11 histone deacetylase 11
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HOOK1 hook microtubule-tethering protein 1
HOXB2 homeobox B2
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
IGFBP6 insulin-like growth factor binding protein 6
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
IPO8 importin 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
JMJD4 jumonji domain containing 4
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD7 potassium channel tetramerization domain containing 7
KIAA0125 KIAA0125
KPNA5 karyopherin alpha 5 (importin alpha 6)
LENEP lens epithelial protein
LHX6 LIM homeobox 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
MCOLN1 mucolipin 1
MXD3 MAX dimerization protein 3
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NPY5R neuropeptide Y receptor Y5
NXPH4 neurexophilin 4
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
PCDHA6 protocadherin alpha 6
PCDHB13 protocadherin beta 13
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PRPH peripherin
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAPSN receptor-associated protein of the synapse
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF2 ring finger protein 2
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPGR retinitis pigmentosa GTPase regulator
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC17A2 solute carrier family 17, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TLN1 talin 1
TMEM121 transmembrane protein 121
TRIM36 tripartite motif containing 36
TSC22D4 TSC22 domain family, member 4
USP18 ubiquitin specific peptidase 18
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZNF480 zinc finger protein 480
ZNF551 zinc finger protein 551
ZNF701 zinc finger protein 701