| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the triprolidine-2376 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APAF1 | apoptotic peptidase activating factor 1 |
| APP | amyloid beta (A4) precursor protein |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATF6B | activating transcription factor 6 beta |
| AURKA | aurora kinase A |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BEST1 | bestrophin 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CALCB | calcitonin-related polypeptide beta |
| CCDC64 | coiled-coil domain containing 64 |
| CD300A | CD300a molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDC25C | cell division cycle 25C |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CFP | complement factor properdin |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CTRC | chymotrypsin C (caldecrin) |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DESI2 | desumoylating isopeptidase 2 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DLX2 | distal-less homeobox 2 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOPEY1 | dopey family member 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFCAB6 | EF-hand calcium binding domain 6 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ELN | elastin |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FAM127B | family with sequence similarity 127, member B |
| FOXO4 | forkhead box O4 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FYB | FYN binding protein |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GYG2 | glycogenin 2 |
| HCFC1 | host cell factor C1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HPSE | heparanase |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IL11 | interleukin 11 |
| IL22 | interleukin 22 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL36 | kelch-like family member 36 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| MCPH1 | microcephalin 1 |
| MTA1 | metastasis associated 1 |
| NDRG2 | NDRG family member 2 |
| NEK1 | NIMA-related kinase 1 |
| NF1 | neurofibromin 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NTM | neurotrimin |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OLFML2B | olfactomedin-like 2B |
| OPRL1 | opiate receptor-like 1 |
| OPTN | optineurin |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLA2G3 | phospholipase A2, group III |
| PLSCR4 | phospholipid scramblase 4 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS23 | protease, serine, 23 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNX1 | runt-related transcription factor 1 |
| SHOX2 | short stature homeobox 2 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SSBP2 | single-stranded DNA binding protein 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TRIM23 | tripartite motif containing 23 |
| TSKS | testis-specific serine kinase substrate |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF500 | zinc finger protein 500 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ABHD11 | abhydrolase domain containing 11 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGO4 | argonaute RISC catalytic component 4 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| BBC3 | BCL2 binding component 3 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CAPN15 | calpain 15 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNT1 | cyclin T1 |
| CCS | copper chaperone for superoxide dismutase |
| CDA | cytidine deaminase |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP97 | centrosomal protein 97kDa |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CST3 | cystatin C |
| DBF4B | DBF4 zinc finger B |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DENND2D | DENN/MADD domain containing 2D |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM163A | family with sequence similarity 163, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FGL2 | fibrinogen-like 2 |
| FHL3 | four and a half LIM domains 3 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HOPX | HOP homeobox |
| IFT46 | intraflagellar transport 46 |
| IL18 | interleukin 18 |
| JUNB | jun B proto-oncogene |
| KIAA0753 | KIAA0753 |
| LACTB2 | lactamase, beta 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MEGF8 | multiple EGF-like-domains 8 |
| MICA | MHC class I polypeptide-related sequence A |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO5C | myosin VC |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OCEL1 | occludin/ELL domain containing 1 |
| OTUD3 | OTU deubiquitinase 3 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PADI1 | peptidyl arginine deiminase, type I |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SCAI | suppressor of cancer cell invasion |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TBC1D4 | TBC1 domain family, member 4 |
| TEC | tec protein tyrosine kinase |
| TK1 | thymidine kinase 1, soluble |
| TLR4 | toll-like receptor 4 |
| TMEM53 | transmembrane protein 53 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| UNC13B | unc-13 homolog B (C. elegans) |
| USP6 | ubiquitin specific peptidase 6 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF276 | zinc finger protein 276 |
| ZNF324 | zinc finger protein 324 |
| ZNF428 | zinc finger protein 428 |
| ZNF696 | zinc finger protein 696 |
| ZNF74 | zinc finger protein 74 |
| ZNF747 | zinc finger protein 747 |
