| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the triprolidine-7408 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADCY6 | adenylate cyclase 6 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ALPK1 | alpha-kinase 1 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CA4 | carbonic anhydrase IV |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CEP72 | centrosomal protein 72kDa |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DOK4 | docking protein 4 |
| DST | dystonin |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| F8 | coagulation factor VIII, procoagulant component |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM212B | family with sequence similarity 212, member B |
| FOXA1 | forkhead box A1 |
| GAR1 | GAR1 ribonucleoprotein |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| HDAC5 | histone deacetylase 5 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HTT | huntingtin |
| IL4R | interleukin 4 receptor |
| KDM5A | lysine (K)-specific demethylase 5A |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LMNA | lamin A/C |
| LOC644450 | uncharacterized LOC644450 |
| LOC730101 | uncharacterized LOC730101 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MBTD1 | mbt domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MGC12488 | |
| MPDZ | multiple PDZ domain protein |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NF2 | neurofibromin 2 (merlin) |
| NKX3-1 | NK3 homeobox 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| PCNX | pecanex homolog (Drosophila) |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLTP | phospholipid transfer protein |
| PODXL2 | podocalyxin-like 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PTRF | polymerase I and transcript release factor |
| RANBP3 | RAN binding protein 3 |
| RARA | retinoic acid receptor, alpha |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPL10 | ribosomal protein L10 |
| SIK2 | salt-inducible kinase 2 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STK17B | serine/threonine kinase 17b |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUGP1 | SURP and G patch domain containing 1 |
| TESK2 | testis-specific kinase 2 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM63A | transmembrane protein 63A |
| TOP3A | topoisomerase (DNA) III alpha |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTF2 | transcription termination factor, RNA polymerase II |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| USP22 | ubiquitin specific peptidase 22 |
| VLDLR | very low density lipoprotein receptor |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF180 | zinc finger protein 180 |
| ZNF432 | zinc finger protein 432 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ADIRF | adipogenesis regulatory factor |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APH1B | APH1B gamma secretase subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BBC3 | BCL2 binding component 3 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CBR4 | carbonyl reductase 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CLDN4 | claudin 4 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRBN | cereblon |
| CRYL1 | crystallin, lambda 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DOCK1 | dedicator of cytokinesis 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM178A | family with sequence similarity 178, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FERMT1 | fermitin family member 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FPGS | folylpolyglutamate synthase |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FUZ | fuzzy planar cell polarity protein |
| FZD4 | frizzled class receptor 4 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4J | histone cluster 1, H4j |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IFT22 | intraflagellar transport 22 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO8 | importin 8 |
| JUNB | jun B proto-oncogene |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRRC20 | leucine rich repeat containing 20 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MMP9 | matrix metallopeptidase 9 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD3 | MAX dimerization protein 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRAF2 | PRA1 domain family, member 2 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB27B | RAB27B, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RNF123 | ring finger protein 123 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SH2D4A | SH2 domain containing 4A |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SREK1IP1 | SREK1-interacting protein 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SYTL2 | synaptotagmin-like 2 |
| TCTN1 | tectonic family member 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM110 | transmembrane protein 110 |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TNRC6B | trinucleotide repeat containing 6B |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRABD | TraB domain containing |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| WDR60 | WD repeat domain 60 |
| XAB2 | XPA binding protein 2 |
| ZNF276 | zinc finger protein 276 |
| ZNF318 | zinc finger protein 318 |
| ZNF516 | zinc finger protein 516 |
| ZNF552 | zinc finger protein 552 |
