trisomy Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description presence of an extra chromosome in an otherwise diploid chromosome set (Mammalian Phenotype Ontology, MP_0004027)
Similar Terms
Downloads & Tools

Genes

77 genes co-occuring with the biological term trisomy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AFP alpha-fetoprotein
AHSG alpha-2-HS-glycoprotein
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANG angiogenin, ribonuclease, RNase A family, 5
APCDD1 adenomatosis polyposis coli down-regulated 1
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BMP2 bone morphogenetic protein 2
CBS cystathionine-beta-synthase
CCND1 cyclin D1
CD19 CD19 molecule
CD34 CD34 molecule
CGA glycoprotein hormones, alpha polypeptide
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CREBBP CREB binding protein
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAS Fas cell surface death receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLT3 fms-related tyrosine kinase 3
FOXP1 forkhead box P1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
HAND2 heart and neural crest derivatives expressed 2
HOXA@ homeobox A cluster
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGF2 insulin-like growth factor 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB7 integrin, beta 7
JAK2 Janus kinase 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
LBH limb bud and heart development
LGALS13 lectin, galactoside-binding, soluble, 13
MN1 meningioma (disrupted in balanced translocation) 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NDNF neuron-derived neurotrophic factor
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NQO1 NAD(P)H dehydrogenase, quinone 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PGF placental growth factor
PLAC4 placenta-specific 4
PRDM16 PR domain containing 16
PTPRC protein tyrosine phosphatase, receptor type, C
REST RE1-silencing transcription factor
RUNX1 runt-related transcription factor 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SHH sonic hedgehog
SLC19A1 solute carrier family 19 (folate transporter), member 1
SOD1 superoxide dismutase 1, soluble
SYNJ1 synaptojanin 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TERC telomerase RNA component
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TP53 tumor protein p53
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VEGFA vascular endothelial growth factor A
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma