troglitazone-1012 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the troglitazone-1012 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM22 ADAM metallopeptidase domain 22
AMT aminomethyltransferase
ANAPC13 anaphase promoting complex subunit 13
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
ATRNL1 attractin-like 1
C3 complement component 3
CA11 carbonic anhydrase XI
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCHCR1 coiled-coil alpha-helical rod protein 1
CDC25C cell division cycle 25C
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CLCF1 cardiotrophin-like cytokine factor 1
CNGB3 cyclic nucleotide gated channel beta 3
COPS8 COP9 signalosome subunit 8
CTAGE5 CTAGE family, member 5
DDIT3 DNA-damage-inducible transcript 3
DIO2 deiodinase, iodothyronine, type II
DNAH3 dynein, axonemal, heavy chain 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSC2 desmocollin 2
DST dystonin
EGR1 early growth response 1
EXTL3 exostosin-like glycosyltransferase 3
FAM184A family with sequence similarity 184, member A
FGFR1 fibroblast growth factor receptor 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FSCN1 fascin actin-bundling protein 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPER1 G protein-coupled estrogen receptor 1
GPR137 G protein-coupled receptor 137
HAUS5 HAUS augmin-like complex, subunit 5
HIST1H3B histone cluster 1, H3b
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IFT38 intraflagellar transport 38
IRAK4 interleukin-1 receptor-associated kinase 4
JAKMIP2 janus kinase and microtubule interacting protein 2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIAA0319L KIAA0319-like
KIF5C kinesin family member 5C
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
KLHL28 kelch-like family member 28
LOC644450 uncharacterized LOC644450
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYRM9 LYR motif containing 9
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK8 mitogen-activated protein kinase 8
MCF2L MCF.2 cell line derived transforming sequence-like
MEF2D myocyte enhancer factor 2D
MINK1 misshapen-like kinase 1
MTAP methylthioadenosine phosphorylase
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
OVGP1 oviductal glycoprotein 1, 120kDa
PBX2 pre-B-cell leukemia homeobox 2
PCDH7 protocadherin 7
PDGFRL platelet-derived growth factor receptor-like
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PITX1 paired-like homeodomain 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTPRS protein tyrosine phosphatase, receptor type, S
QSER1 glutamine and serine rich 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RND1 Rho family GTPase 1
RNF208 ring finger protein 208
RREB1 ras responsive element binding protein 1
RTN2 reticulon 2
SFTPB surfactant protein B
SIX1 SIX homeobox 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
STK11 serine/threonine kinase 11
TAOK3 TAO kinase 3
TBC1D17 TBC1 domain family, member 17
TIMELESS timeless circadian clock
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TTC38 tetratricopeptide repeat domain 38
UTRN utrophin
VAV1 vav 1 guanine nucleotide exchange factor
WIPI2 WD repeat domain, phosphoinositide interacting 2
WSB1 WD repeat and SOCS box containing 1
ZFP30 ZFP30 zinc finger protein
ZNF10 zinc finger protein 10
ZNF205 zinc finger protein 205
ZNF235 zinc finger protein 235
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTN4 actinin, alpha 4
ACYP2 acylphosphatase 2, muscle type
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
AKAP12 A kinase (PRKA) anchor protein 12
ALPK1 alpha-kinase 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANP32A-IT1 ANP32A intronic transcript 1
BBS7 Bardet-Biedl syndrome 7
BCOR BCL6 corepressor
BMP4 bone morphogenetic protein 4
C16ORF45 chromosome 16 open reading frame 45
C16ORF59 chromosome 16 open reading frame 59
C1ORF216 chromosome 1 open reading frame 216
C6ORF47 chromosome 6 open reading frame 47
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CD3EAP CD3e molecule, epsilon associated protein
CENPT centromere protein T
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
COQ6 coenzyme Q6 monooxygenase
CRABP1 cellular retinoic acid binding protein 1
CUEDC1 CUE domain containing 1
DCP1A decapping mRNA 1A
DIXDC1 DIX domain containing 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EPPK1 epiplakin 1
FBRS fibrosin
FER fer (fps/fes related) tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLB1L galactosidase, beta 1-like
GPATCH3 G patch domain containing 3
GRTP1 growth hormone regulated TBC protein 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
HPS6 Hermansky-Pudlak syndrome 6
IRF7 interferon regulatory factor 7
ITPKB inositol-trisphosphate 3-kinase B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LMCD1 LIM and cysteine-rich domains 1
LOC642236 FSHD region gene 1 pseudogene
MAP1S microtubule-associated protein 1S
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPKBP1 mitogen-activated protein kinase binding protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNX1 motor neuron and pancreas homeobox 1
MPI mannose phosphate isomerase
MTA2 metastasis associated 1 family, member 2
MTCL1 microtubule crosslinking factor 1
MVD mevalonate (diphospho) decarboxylase
NAIP NLR family, apoptosis inhibitory protein
NDE1 nudE neurodevelopment protein 1
NECAP2 NECAP endocytosis associated 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PCDHA6 protocadherin alpha 6
PGP phosphoglycolate phosphatase
PGR progesterone receptor
PPP6R2 protein phosphatase 6, regulatory subunit 2
PYCRL pyrroline-5-carboxylate reductase-like
RAB33B RAB33B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPUSD2 RNA pseudouridylate synthase domain containing 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIDT1 SID1 transmembrane family, member 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRYD7 SPRY domain containing 7
STARD5 StAR-related lipid transfer (START) domain containing 5
STBD1 starch binding domain 1
STRN striatin, calmodulin binding protein
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM62 transmembrane protein 62
TNS2 tensin 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBQLN4 ubiquilin 4
VEGFC vascular endothelial growth factor C
XK X-linked Kx blood group
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H3 zinc finger CCCH-type containing 3
ZNF282 zinc finger protein 282
ZNF665 zinc finger protein 665