| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the troglitazone-1173 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACAN | aggrecan |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| BAX | BCL2-associated X protein |
| BCL7A | B-cell CLL/lymphoma 7A |
| CACTIN | cactin, spliceosome C complex subunit |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDC25C | cell division cycle 25C |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRYL1 | crystallin, lambda 1 |
| CTSH | cathepsin H |
| CYB561 | cytochrome b561 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DAPK1 | death-associated protein kinase 1 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DYM | dymeclin |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ELMO2 | engulfment and cell motility 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM50B | family with sequence similarity 50, member B |
| FCMR | Fc fragment of IgM receptor |
| FLNB | filamin B, beta |
| GAS7 | growth arrest-specific 7 |
| GCFC2 | GC-rich sequence DNA-binding factor 2 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| H2AFX | H2A histone family, member X |
| HIST1H2BN | histone cluster 1, H2bn |
| HMOX2 | heme oxygenase 2 |
| HOXA9 | homeobox A9 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL24 | interleukin 24 |
| IL27RA | interleukin 27 receptor, alpha |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KLHDC10 | kelch domain containing 10 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) |
| MCM9 | minichromosome maintenance complex component 9 |
| METTL7A | methyltransferase like 7A |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MSRB2 | methionine sulfoxide reductase B2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC3A | mucin 3A, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| NRP1 | neuropilin 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARD3 | par-3 family cell polarity regulator |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHF20 | PHD finger protein 20 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RBM48 | RNA binding motif protein 48 |
| RC3H2 | ring finger and CCCH-type domains 2 |
| RHEB | Ras homolog enriched in brain |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RUNX1 | runt-related transcription factor 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCARB1 | scavenger receptor class B, member 1 |
| SGSM3 | small G protein signaling modulator 3 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SMAD5 | SMAD family member 5 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPN | sialophorin |
| STK3 | serine/threonine kinase 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYNJ2 | synaptojanin 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRAIP | TRAF interacting protein |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TYRO3 | TYRO3 protein tyrosine kinase |
| UNC119B | unc-119 homolog B (C. elegans) |
| UNC5B | unc-5 homolog B (C. elegans) |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF345 | zinc finger protein 345 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADM | adrenomedullin |
| AHR | aryl hydrocarbon receptor |
| ARG1 | arginase 1 |
| ATF3 | activating transcription factor 3 |
| ATG2A | autophagy related 2A |
| BLM | Bloom syndrome, RecQ helicase-like |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNJ | cyclin J |
| CD69 | CD69 molecule |
| CEL | carboxyl ester lipase |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DOLK | dolichol kinase |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ETV4 | ets variant 4 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FADS2 | fatty acid desaturase 2 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXO3 | forkhead box O3 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HHLA3 | HERV-H LTR-associating 3 |
| HLX | H2.0-like homeobox |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL4R | interleukin 4 receptor |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| JMJD4 | jumonji domain containing 4 |
| JUNB | jun B proto-oncogene |
| KIAA0754 | KIAA0754 |
| LRRC47 | leucine rich repeat containing 47 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSP1 | lymphocyte-specific protein 1 |
| MACROD1 | MACRO domain containing 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MRGBP | MRG/MORF4L binding protein |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NCS1 | neuronal calcium sensor 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| POR | P450 (cytochrome) oxidoreductase |
| PTDSS2 | phosphatidylserine synthase 2 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RGS13 | regulator of G-protein signaling 13 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RGS2 | regulator of G-protein signaling 2 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RPA4 | replication protein A4, 30kDa |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAP | SREBF chaperone |
| SERINC5 | serine incorporator 5 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SOAT1 | sterol O-acyltransferase 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STBD1 | starch binding domain 1 |
| TEC | tec protein tyrosine kinase |
| TERT | telomerase reverse transcriptase |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMEM156 | transmembrane protein 156 |
| TMEM209 | transmembrane protein 209 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TPCN1 | two pore segment channel 1 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM16 | tripartite motif containing 16 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TUBA3C | tubulin, alpha 3c |
| TXLNG | taxilin gamma |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| UPP1 | uridine phosphorylase 1 |
| WWC2 | WW and C2 domain containing 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF282 | zinc finger protein 282 |
| ZNF468 | zinc finger protein 468 |
| ZNF528 | zinc finger protein 528 |
| ZNF675 | zinc finger protein 675 |
