troglitazone-1232 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the troglitazone-1232 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADGRF5 adhesion G protein-coupled receptor F5
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARHGAP26 Rho GTPase activating protein 26
ASB13 ankyrin repeat and SOCS box containing 13
C3 complement component 3
C7ORF43 chromosome 7 open reading frame 43
CCNA1 cyclin A1
CDH7 cadherin 7, type 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLEC4E C-type lectin domain family 4, member E
CPNE7 copine VII
CTNS cystinosin, lysosomal cystine transporter
DHODH dihydroorotate dehydrogenase (quinone)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
ELOVL4 ELOVL fatty acid elongase 4
FA2H fatty acid 2-hydroxylase
FABP4 fatty acid binding protein 4, adipocyte
FGF2 fibroblast growth factor 2 (basic)
FYB FYN binding protein
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GSK3A glycogen synthase kinase 3 alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BJ histone cluster 1, H2bj
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IL1B interleukin 1, beta
IL37 interleukin 37
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
LAMA4 laminin, alpha 4
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPIN1 lipin 1
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MAP2K3 mitogen-activated protein kinase kinase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2L3 nuclear factor, erythroid 2-like 3
NLE1 notchless homolog 1 (Drosophila)
NPY2R neuropeptide Y receptor Y2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLIN2 perilipin 2
PLSCR4 phospholipid scramblase 4
PML promyelocytic leukemia
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCD protein kinase C, delta
PSD4 pleckstrin and Sec7 domain containing 4
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB31 RAB31, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC2 syndecan 2
SFN stratifin
SH2D2A SH2 domain containing 2A
SIKE1 suppressor of IKBKE 1
SIM2 single-minded family bHLH transcription factor 2
SIX1 SIX homeobox 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SORBS1 sorbin and SH3 domain containing 1
TBC1D17 TBC1 domain family, member 17
TBC1D30 TBC1 domain family, member 30
THBD thrombomodulin
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRMT61A tRNA methyltransferase 61A
TSKU tsukushi, small leucine rich proteoglycan
TSPAN12 tetraspanin 12
TTC38 tetratricopeptide repeat domain 38
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
BAHD1 bromo adjacent homology domain containing 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIN3 bridging integrator 3
BMP4 bone morphogenetic protein 4
C1ORF115 chromosome 1 open reading frame 115
CAMTA2 calmodulin binding transcription activator 2
CARD8 caspase recruitment domain family, member 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CNN2 calponin 2
COL5A2 collagen, type V, alpha 2
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRYL1 crystallin, lambda 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DAAM1 dishevelled associated activator of morphogenesis 1
EDN1 endothelin 1
EMD emerin
ESM1 endothelial cell-specific molecule 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM102A family with sequence similarity 102, member A
FAM46A family with sequence similarity 46, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO46 F-box protein 46
FOXD1 forkhead box D1
FZD8 frizzled class receptor 8
GPALPP1 GPALPP motifs containing 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRPR gastrin-releasing peptide receptor
HMHA1 histocompatibility (minor) HA-1
HOXA1 homeobox A1
HOXC4 homeobox C4
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL17RA interleukin 17 receptor A
IL33 interleukin 33
ISL1 ISL LIM homeobox 1
KDM3A lysine (K)-specific demethylase 3A
KLK7 kallikrein-related peptidase 7
MALL mal, T-cell differentiation protein-like
MMP13 matrix metallopeptidase 13
MOCS3 molybdenum cofactor synthesis 3
MON1B MON1 secretory trafficking family member B
MPI mannose phosphate isomerase
MTERF4 mitochondrial transcription termination factor 4
MTG1 mitochondrial ribosome-associated GTPase 1
NCS1 neuronal calcium sensor 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
ORC1 origin recognition complex, subunit 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALMD palmdelphin
PC pyruvate carboxylase
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLIN3 perilipin 3
PLK2 polo-like kinase 2
PNRC1 proline-rich nuclear receptor coactivator 1
PPAP2B phosphatidic acid phosphatase type 2B
PPARG peroxisome proliferator-activated receptor gamma
PPL periplakin
PRR15L proline rich 15-like
PTGES2 prostaglandin E synthase 2
PTGFR prostaglandin F receptor (FP)
RGS2 regulator of G-protein signaling 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SALL2 spalt-like transcription factor 2
SAMD9 sterile alpha motif domain containing 9
SCUBE3 signal peptide, CUB domain, EGF-like 3
SENP7 SUMO1/sentrin specific peptidase 7
SLC22A18 solute carrier family 22, member 18
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPATA7 spermatogenesis associated 7
SREBF1 sterol regulatory element binding transcription factor 1
STAG3 stromal antigen 3
SYTL2 synaptotagmin-like 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TESK2 testis-specific kinase 2
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPCN1 two pore segment channel 1
TRAPPC11 trafficking protein particle complex 11
TRIM68 tripartite motif containing 68
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VEGFC vascular endothelial growth factor C
ZBTB38 zinc finger and BTB domain containing 38
ZBTB44 zinc finger and BTB domain containing 44
ZNF629 zinc finger protein 629