troglitazone-370 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the troglitazone-370 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACOT11 acyl-CoA thioesterase 11
ACOT9 acyl-CoA thioesterase 9
ADAM20 ADAM metallopeptidase domain 20
ADAM22 ADAM metallopeptidase domain 22
AFF2 AF4/FMR2 family, member 2
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C2 aldo-keto reductase family 1, member C2
ANP32A-IT1 ANP32A intronic transcript 1
AQP9 aquaporin 9
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATG13 autophagy related 13
AXIN1 axin 1
BIN2 bridging integrator 2
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BST1 bone marrow stromal cell antigen 1
C20ORF27 chromosome 20 open reading frame 27
C2CD3 C2 calcium-dependent domain containing 3
C7ORF26 chromosome 7 open reading frame 26
CACFD1 calcium channel flower domain containing 1
CALHM2 calcium homeostasis modulator 2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CDC42 cell division cycle 42
CECR1 cat eye syndrome chromosome region, candidate 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLDN17 claudin 17
CLIC5 chloride intracellular channel 5
CNPPD1 cyclin Pas1/PHO80 domain containing 1
DUSP2 dual specificity phosphatase 2
EHD3 EH-domain containing 3
EMC1 ER membrane protein complex subunit 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHB3 EPH receptor B3
F10 coagulation factor X
FAM189B family with sequence similarity 189, member B
FASTK Fas-activated serine/threonine kinase
FBXO42 F-box protein 42
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCHO1 FCH domain only 1
FLOT2 flotillin 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G6PC3 glucose 6 phosphatase, catalytic, 3
GAS7 growth arrest-specific 7
GM2A GM2 ganglioside activator
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR153 G protein-coupled receptor 153
GRK5 G protein-coupled receptor kinase 5
HOXA10 homeobox A10
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IRAK4 interleukin-1 receptor-associated kinase 4
IRGQ immunity-related GTPase family, Q
IVD isovaleryl-CoA dehydrogenase
JOSD1 Josephin domain containing 1
KDM4B lysine (K)-specific demethylase 4B
KLF12 Kruppel-like factor 12
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MCF2L MCF.2 cell line derived transforming sequence-like
MUC2 mucin 2, oligomeric mucus/gel-forming
MXD4 MAX dimerization protein 4
MYL10 myosin, light chain 10, regulatory
MYT1 myelin transcription factor 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOL12 nucleolar protein 12
NPAT nuclear protein, ataxia-telangiectasia locus
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OMG oligodendrocyte myelin glycoprotein
PKN1 protein kinase N1
PLCB2 phospholipase C, beta 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTGES prostaglandin E synthase
PVT1 Pvt1 oncogene (non-protein coding)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAG S-antigen; retina and pineal gland (arrestin)
SFTPC surfactant protein C
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX2 SRY (sex determining region Y)-box 2
SPN sialophorin
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TESK2 testis-specific kinase 2
TFE3 transcription factor binding to IGHM enhancer 3
TG thyroglobulin
TRABD TraB domain containing
TSSC4 tumor suppressing subtransferable candidate 4
VAC14 Vac14 homolog (S. cerevisiae)
VIPR2 vasoactive intestinal peptide receptor 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WWOX WW domain containing oxidoreductase
ZMAT3 zinc finger, matrin-type 3
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADM2 adrenomedullin 2
ANKRD55 ankyrin repeat domain 55
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BNC2 basonuclin 2
C14ORF159 chromosome 14 open reading frame 159
C1ORF105 chromosome 1 open reading frame 105
C1ORF95 chromosome 1 open reading frame 95
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CA6 carbonic anhydrase VI
CA7 carbonic anhydrase VII
CAMTA2 calmodulin binding transcription activator 2
CD207 CD207 molecule, langerin
CHRM2 cholinergic receptor, muscarinic 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DSG2 desmoglein 2
ECE2 endothelin converting enzyme 2
EMILIN2 elastin microfibril interfacer 2
F11 coagulation factor XI
FMO2 flavin containing monooxygenase 2 (non-functional)
FSCN3 fascin actin-bundling protein 3, testicular
GLB1L2 galactosidase, beta 1-like 2
GPATCH1 G patch domain containing 1
HOOK2 hook microtubule-tethering protein 2
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HYI hydroxypyruvate isomerase (putative)
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL10 interleukin 10
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNIP1 Kv channel interacting protein 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA1549L KIAA1549-like
KRT32 keratin 32, type I
KRT9 keratin 9, type I
LGALS13 lectin, galactoside-binding, soluble, 13
LINC00216 long intergenic non-protein coding RNA 216
LPPR1 lipid phosphate phosphatase-related protein type 1
LUZP4 leucine zipper protein 4
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEC1 melanoma antigen family C1
MAPK10 mitogen-activated protein kinase 10
MBTPS2 membrane-bound transcription factor peptidase, site 2
MNT MAX network transcriptional repressor
MTERF4 mitochondrial transcription termination factor 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOZ1 myozenin 1
NNAT neuronatin
PADI1 peptidyl arginine deiminase, type I
PALM paralemmin
PARD6A par-6 family cell polarity regulator alpha
PEX12 peroxisomal biogenesis factor 12
PICK1 protein interacting with PRKCA 1
PLA2G2E phospholipase A2, group IIE
PLVAP plasmalemma vesicle associated protein
PROL1 proline rich, lacrimal 1
PRPH peripherin
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PZP pregnancy-zone protein
RFPL2 ret finger protein-like 2
RIPK4 receptor-interacting serine-threonine kinase 4
SEC14L5 SEC14-like 5 (S. cerevisiae)
SETMAR SET domain and mariner transposase fusion gene
SIX6 SIX homeobox 6
SLC35E3 solute carrier family 35, member E3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPDL1 spindle apparatus coiled-coil protein 1
SREBF1 sterol regulatory element binding transcription factor 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TJP2 tight junction protein 2
TMEM206 transmembrane protein 206
TMEM209 transmembrane protein 209
TRIM32 tripartite motif containing 32
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPO2 translocator protein 2
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
VPREB3 pre-B lymphocyte 3
WDR62 WD repeat domain 62
ZBTB39 zinc finger and BTB domain containing 39
ZNF185 zinc finger protein 185 (LIM domain)
ZNF232 zinc finger protein 232
ZNF253 zinc finger protein 253
ZNF480 zinc finger protein 480
ZNF557 zinc finger protein 557
ZNF8 zinc finger protein 8
ZNF85 zinc finger protein 85