troglitazone-431 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the troglitazone-431 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADM2 adrenomedullin 2
AMBRA1 autophagy/beclin-1 regulator 1
ANGPTL4 angiopoietin-like 4
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
APOC1 apolipoprotein C-I
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG13 autophagy related 13
BCR breakpoint cluster region
C20ORF27 chromosome 20 open reading frame 27
C2CD2 C2 calcium-dependent domain containing 2
C2CD2L C2CD2-like
CALB2 calbindin 2
CD300C CD300c molecule
CD302 CD302 molecule
CD6 CD6 molecule
CDC25A cell division cycle 25A
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPE carboxypeptidase E
CRMP1 collapsin response mediator protein 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAXX death-domain associated protein
DGKD diacylglycerol kinase, delta 130kDa
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOK3 docking protein 3
DPEP1 dipeptidase 1 (renal)
DUS2 dihydrouridine synthase 2
E2F5 E2F transcription factor 5, p130-binding
FA2H fatty acid 2-hydroxylase
FABP4 fatty acid binding protein 4, adipocyte
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIMAP5 GTPase, IMAP family member 5
GLTSCR1 glioma tumor suppressor candidate region gene 1
GM2A GM2 ganglioside activator
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR107 G protein-coupled receptor 107
HBD hemoglobin, delta
HLA-DRA major histocompatibility complex, class II, DR alpha
HPSE heparanase
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
ICAM1 intercellular adhesion molecule 1
IFFO1 intermediate filament family orphan 1
IFI35 interferon-induced protein 35
IL1B interleukin 1, beta
IRAK4 interleukin-1 receptor-associated kinase 4
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL25 kelch-like family member 25
KXD1 KxDL motif containing 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LPIN1 lipin 1
LRP6 low density lipoprotein receptor-related protein 6
MVB12B multivesicular body subunit 12B
NAT6 N-acetyltransferase 6 (GCN5-related)
NBEAL2 neurobeachin-like 2
NCALD neurocalcin delta
NCR2 natural cytotoxicity triggering receptor 2
NOL8 nucleolar protein 8
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSGIN1 oxidative stress induced growth inhibitor 1
PADI2 peptidyl arginine deiminase, type II
PARG poly (ADP-ribose) glycohydrolase
PCBP2 poly(rC) binding protein 2
PHF20 PHD finger protein 20
PLIN2 perilipin 2
POGZ pogo transposable element with ZNF domain
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPARD peroxisome proliferator-activated receptor delta
PRKCD protein kinase C, delta
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
QDPR quinoid dihydropteridine reductase
RAD54L RAD54-like (S. cerevisiae)
RBKS ribokinase
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RNF141 ring finger protein 141
RPS2 ribosomal protein S2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLMO2 slowmo homolog 2 (Drosophila)
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
STXBP5L syntaxin binding protein 5-like
TBX5 T-box 5
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM58 tripartite motif containing 58
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UMPS uridine monophosphate synthetase
USF2 upstream transcription factor 2, c-fos interacting

decreased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
AHDC1 AT hook, DNA binding motif, containing 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APOL6 apolipoprotein L, 6
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ASIP agouti signaling protein
ATXN2 ataxin 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BMPR1B bone morphogenetic protein receptor, type IB
C14ORF79 chromosome 14 open reading frame 79
C2CD5 C2 calcium-dependent domain containing 5
CA5BP1 carbonic anhydrase VB pseudogene 1
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCDC176 coiled-coil domain containing 176
CD83 CD83 molecule
CDK7 cyclin-dependent kinase 7
CFAP70 cilia and flagella associated protein 70
CHRM3 cholinergic receptor, muscarinic 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLIP4 CAP-GLY domain containing linker protein family, member 4
COQ4 coenzyme Q4
CRELD1 cysteine-rich with EGF-like domains 1
CTGF connective tissue growth factor
CTRB2 chymotrypsinogen B2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
EDC3 enhancer of mRNA decapping 3
EGFL7 EGF-like-domain, multiple 7
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM114A2 family with sequence similarity 114, member A2
FAM155A family with sequence similarity 155, member A
FAM192A family with sequence similarity 192, member A
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FKBP8 FK506 binding protein 8, 38kDa
FZD8 frizzled class receptor 8
GALR3 galanin receptor 3
GALT galactose-1-phosphate uridylyltransferase
GAMT guanidinoacetate N-methyltransferase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCKR glucokinase (hexokinase 4) regulator
HDAC5 histone deacetylase 5
HIST1H2BI histone cluster 1, H2bi
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JOSD1 Josephin domain containing 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIFAP3 kinesin-associated protein 3
KLHL28 kelch-like family member 28
KRT85 keratin 85, type II
LENEP lens epithelial protein
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRRC37A2 leucine rich repeat containing 37, member A2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MPV17 MpV17 mitochondrial inner membrane protein
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOZ3 myozenin 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PACS1 phosphofurin acidic cluster sorting protein 1
PFAS phosphoribosylformylglycinamidine synthase
PISD phosphatidylserine decarboxylase
PKD2L1 polycystic kidney disease 2-like 1
PLA2G10 phospholipase A2, group X
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLK2 polo-like kinase 2
PPAP2B phosphatidic acid phosphatase type 2B
PPARG peroxisome proliferator-activated receptor gamma
PRR16 proline rich 16
PTK7 protein tyrosine kinase 7 (inactive)
PTX3 pentraxin 3, long
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SATB1 SATB homeobox 1
SFTPA2 surfactant protein A2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIRT2 sirtuin 2
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMA4 glucuronidase, beta pseudogene
STAT5A signal transducer and activator of transcription 5A
TET3 tet methylcytosine dioxygenase 3
TMEM204 transmembrane protein 204
TMEM8A transmembrane protein 8A
TNNI3 troponin I type 3 (cardiac)
TNRC6B trinucleotide repeat containing 6B
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VEGFC vascular endothelial growth factor C
VEZT vezatin, adherens junctions transmembrane protein
WDR19 WD repeat domain 19
WDR91 WD repeat domain 91
ZBED1 zinc finger, BED-type containing 1
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF430 zinc finger protein 430
ZNF804A zinc finger protein 804A