| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the troglitazone-4456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADCK2 | aarF domain containing kinase 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANGPTL4 | angiopoietin-like 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| ATP10A | ATPase, class V, type 10A |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CCDC64 | coiled-coil domain containing 64 |
| CCNA1 | cyclin A1 |
| CCNK | cyclin K |
| CD1A | CD1a molecule |
| CDH7 | cadherin 7, type 2 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EGR1 | early growth response 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EXOSC1 | exosome component 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FCAR | Fc fragment of IgA receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FYB | FYN binding protein |
| GK | glycerol kinase |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IL1B | interleukin 1, beta |
| IRS2 | insulin receptor substrate 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUN | jun proto-oncogene |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KLF13 | Kruppel-like factor 13 |
| KRT37 | keratin 37, type I |
| LAMA4 | laminin, alpha 4 |
| LPIN1 | lipin 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NNMT | nicotinamide N-methyltransferase |
| NPY2R | neuropeptide Y receptor Y2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDE10A | phosphodiesterase 10A |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PKP4 | plakophilin 4 |
| PLIN2 | perilipin 2 |
| PLK3 | polo-like kinase 3 |
| PODNL1 | podocan-like 1 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRKCD | protein kinase C, delta |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTGES | prostaglandin E synthase |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB36 | RAB36, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAP1GAP | RAP1 GTPase activating protein |
| RGS4 | regulator of G-protein signaling 4 |
| RHOB | ras homolog family member B |
| RNF32 | ring finger protein 32 |
| RUNX1 | runt-related transcription factor 1 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SIX3 | SIX homeobox 3 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAT4 | signal transducer and activator of transcription 4 |
| STK17B | serine/threonine kinase 17b |
| STOML1 | stomatin (EPB72)-like 1 |
| TLN2 | talin 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRIM14 | tripartite motif containing 14 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARSB | arylsulfatase B |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BDNF | brain-derived neurotrophic factor |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BNC1 | basonuclin 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C1R | complement component 1, r subcomponent |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CISH | cytokine inducible SH2-containing protein |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CTGF | connective tissue growth factor |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEAF1 | DEAF1 transcription factor |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EAF2 | ELL associated factor 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM46A | family with sequence similarity 46, member A |
| FZD8 | frizzled class receptor 8 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GRPR | gastrin-releasing peptide receptor |
| HDAC7 | histone deacetylase 7 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA1 | homeobox A1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL18 | interleukin 18 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL33 | interleukin 33 |
| INHBB | inhibin, beta B |
| IPP | intracisternal A particle-promoted polypeptide |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MCOLN3 | mucolipin 3 |
| MEIS1 | Meis homeobox 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MPI | mannose phosphate isomerase |
| MUC3B | mucin 3B, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| NCALD | neurocalcin delta |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| OLFML2B | olfactomedin-like 2B |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLAT | plasminogen activator, tissue |
| PLK2 | polo-like kinase 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRR15L | proline rich 15-like |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RGS2 | regulator of G-protein signaling 2 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCEL | sciellin |
| SELL | selectin L |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC46A3 | solute carrier family 46, member 3 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAGLN3 | transgelin 3 |
| TMEM156 | transmembrane protein 156 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TREX1 | three prime repair exonuclease 1 |
| TRIB2 | tribbles pseudokinase 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
