| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the troleandomycin-1465 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADORA1 | adenosine A1 receptor |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATN1 | atrophin 1 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BIN1 | bridging integrator 1 |
| BMP15 | bone morphogenetic protein 15 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CD53 | CD53 molecule |
| CEP135 | centrosomal protein 135kDa |
| COL21A1 | collagen, type XXI, alpha 1 |
| CORT | cortistatin |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXORF21 | chromosome X open reading frame 21 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DMPK | dystrophia myotonica-protein kinase |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EDNRB | endothelin receptor type B |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ESR1 | estrogen receptor 1 |
| ETNK2 | ethanolamine kinase 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBLN1 | fibulin 1 |
| FBXO4 | F-box protein 4 |
| FGF23 | fibroblast growth factor 23 |
| FLJ42627 | uncharacterized LOC645644 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GDF5 | growth differentiation factor 5 |
| GLRX3 | glutaredoxin 3 |
| GMPR | guanosine monophosphate reductase |
| HLA-E | major histocompatibility complex, class I, E |
| IDS | iduronate 2-sulfatase |
| IFNA17 | interferon, alpha 17 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IQCE | IQ motif containing E |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLF12 | Kruppel-like factor 12 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NKG7 | natural killer cell granule protein 7 |
| NXPH3 | neurexophilin 3 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PITX1 | paired-like homeodomain 1 |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLIN2 | perilipin 2 |
| PLXNB3 | plexin B3 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF122 | ring finger protein 122 |
| RPS14 | ribosomal protein S14 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMC4 | structural maintenance of chromosomes 4 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SYMPK | symplekin |
| TBC1D2 | TBC1 domain family, member 2 |
| TCP10 | t-complex 10 |
| TMEM121 | transmembrane protein 121 |
| TMEM259 | transmembrane protein 259 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAF3IP2 | TRAF3 interacting protein 2 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TWF2 | twinfilin actin binding protein 2 |
| UBQLN4 | ubiquilin 4 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF250 | zinc finger protein 250 |
| ZNF324 | zinc finger protein 324 |
| ZNF329 | zinc finger protein 329 |
| ZNF446 | zinc finger protein 446 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AIM1 | absent in melanoma 1 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CAPRIN2 | caprin family member 2 |
| CBX7 | chromobox homolog 7 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DOCK1 | dedicator of cytokinesis 1 |
| DSE | dermatan sulfate epimerase |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| FA2H | fatty acid 2-hydroxylase |
| FAM188A | family with sequence similarity 188, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FKBP5 | FK506 binding protein 5 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GSTT1 | glutathione S-transferase theta 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IL17RA | interleukin 17 receptor A |
| IRF6 | interferon regulatory factor 6 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAP3 | leucine aminopeptidase 3 |
| LINS | lines homolog (Drosophila) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MED22 | mediator complex subunit 22 |
| MEFV | Mediterranean fever |
| METTL16 | methyltransferase like 16 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NKX3-2 | NK3 homeobox 2 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OLFML2A | olfactomedin-like 2A |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDZRN3 | PDZ domain containing ring finger 3 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 |
| PRR3 | proline rich 3 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBL1 | retinoblastoma-like 1 |
| RNF2 | ring finger protein 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPANXC | SPANX family, member C |
| SPRYD7 | SPRY domain containing 7 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TEAD3 | TEA domain family member 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLN1 | talin 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TOM1L1 | target of myb1 (chicken)-like 1 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TRAIP | TRAF interacting protein |
| TSPYL2 | TSPY-like 2 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| VEGFB | vascular endothelial growth factor B |
| WASF1 | WAS protein family, member 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF211 | zinc finger protein 211 |
| ZNF34 | zinc finger protein 34 |
| ZNF442 | zinc finger protein 442 |
| ZNF552 | zinc finger protein 552 |
| ZNF571 | zinc finger protein 571 |
| ZNF668 | zinc finger protein 668 |
| ZNF787 | zinc finger protein 787 |
