trophectoderm Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Trophoblast: esp : the outer layer of the mammalian blastocyst after differentiation of the ectoderm, mesoderm, and endoderm when the outer layer is continuous with the ectoderm of the embryo. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001840)
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Genes

371 proteins co-occuring with the tissue trophectoderm in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CDX2 caudal type homeobox 2 2.65081
NANOG Nanog homeobox 2.03375
POU5F1 POU class 5 homeobox 1 1.81839
TRO trophinin 1.796
EOMES eomesodermin 1.79347
BYSL bystin-like 1.77932
GATA6 GATA binding protein 6 1.64957
FGF4 fibroblast growth factor 4 1.64807
TROAP trophinin associated protein 1.62207
ELF5 E74-like factor 5 (ets domain transcription factor) 1.60912
POU5F1B POU class 5 homeobox 1B 1.52617
OTP orthopedia homeobox 1.33184
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.28547
SOX2 SRY (sex determining region Y)-box 2 1.28098
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 1.27605
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.23093
HMX2 H6 family homeobox 2 1.19311
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.19311
GATA4 GATA binding protein 4 1.19223
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.16382
RPL7L1 ribosomal protein L7-like 1 1.14875
RBM19 RNA binding motif protein 19 1.14166
ASCL2 achaete-scute family bHLH transcription factor 2 1.11376
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.09253
OXTR oxytocin receptor 1.08501
CGN cingulin 1.07044
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.06294
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.03961
WDR74 WD repeat domain 74 1.02644
FN1 fibronectin 1 0.997166
HAND1 heart and neural crest derivatives expressed 1 0.994554
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.992379
RPS6 ribosomal protein S6 0.991944
EED embryonic ectoderm development 0.980217
TJP1 tight junction protein 1 0.96809
LAMA1 laminin, alpha 1 0.967657
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.941355
AMOTL2 angiomotin like 2 0.940066
BMP4 bone morphogenetic protein 4 0.937917
NODAL nodal growth differentiation factor 0.911373
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.910946
CDX4 caudal type homeobox 4 0.907961
ITGB5 integrin, beta 5 0.905831
ZFP42 ZFP42 zinc finger protein 0.900296
CSH2 chorionic somatomammotropin hormone 2 0.893072
AGMAT agmatine ureohydrolase (agmatinase) 0.891798
OOEP oocyte expressed protein 0.88671
PARD6B par-6 family cell polarity regulator beta 0.883321
KRT18 keratin 18, type I 0.878666
AMOT angiomotin 0.876129
SLC38A6 solute carrier family 38, member 6 0.868107
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.867686
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.865577
GPI glucose-6-phosphate isomerase 0.862627
SETDB1 SET domain, bifurcated 1 0.858837
DPPA4 developmental pluripotency associated 4 0.850425
PRR15 proline rich 15 0.843706
DPPA2 developmental pluripotency associated 2 0.83951
GJD4 gap junction protein, delta 4, 40.1kDa 0.828616
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.823594
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 0.817322
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.814815
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.801459
RFPL1 ret finger protein-like 1 0.796458
RSAD2 radical S-adenosyl methionine domain containing 2 0.795208
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.793543
IQGAP2 IQ motif containing GTPase activating protein 2 0.793126
FGFR2 fibroblast growth factor receptor 2 0.790628
H3F3B H3 histone, family 3B (H3.3B) 0.788964
H3F3A H3 histone, family 3A 0.788964
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.77857
TJP2 tight junction protein 2 0.774004
CNOT3 CCR4-NOT transcription complex, subunit 3 0.766539
IFNA1 interferon, alpha 1 0.760742
HBEGF heparin-binding EGF-like growth factor 0.7595
MBD3L2 methyl-CpG binding domain protein 3-like 2 0.756191
GJB3 gap junction protein, beta 3, 31kDa 0.751231
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.746689
DNAH8 dynein, axonemal, heavy chain 8 0.740503
ISM2 isthmin 2 0.74009
SOX17 SRY (sex determining region Y)-box 17 0.730208
KDM8 lysine (K)-specific demethylase 8 0.726918
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.726507
WNT7A wingless-type MMTV integration site family, member 7A 0.725685
OCLN occludin 0.719934
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 0.717061
CUZD1 CUB and zona pellucida-like domains 1 0.71542
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.714189
SPP1 secreted phosphoprotein 1 0.711729
TEAD4 TEA domain family member 4 0.705583
ITGA8 integrin, alpha 8 0.699035
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.697808
NDUFA4 NDUFA4, mitochondrial complex associated 0.695354
ECEL1 endothelin converting enzyme-like 1 0.694537
OVOL2 ovo-like zinc finger 2 0.691676
COX7B cytochrome c oxidase subunit VIIb 0.690859
ISG15 ISG15 ubiquitin-like modifier 0.690451
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.685551
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.683103
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.678617
GATA2 GATA binding protein 2 0.67821
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.677803
TEX11 testis expressed 11 0.673321
FGF7 fibroblast growth factor 7 0.666809
AHCTF1 AT hook containing transcription factor 1 0.662336
AHNAK AHNAK nucleoprotein 0.656648
PRKCD protein kinase C, delta 0.654618
PGK1 phosphoglycerate kinase 1 0.652994
PGR progesterone receptor 0.650154
PADI6 peptidyl arginine deiminase, type VI 0.644884
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.62991
LEFTY1 left-right determination factor 1 0.61941
DSP desmoplakin 0.617796
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.617393
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.611346
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.608527
YY2 YY2 transcription factor 0.606916
TEAD2 TEA domain family member 2 0.604099
ITGA7 integrin, alpha 7 0.602892
TGFB2 transforming growth factor, beta 2 0.597666
DVL3 dishevelled segment polarity protein 3 0.596862
NMI N-myc (and STAT) interactor 0.596862
GCM1 glial cells missing homolog 1 (Drosophila) 0.596058
YAF2 YY1 associated factor 2 0.596058
IGF1 insulin-like growth factor 1 (somatomedin C) 0.595656
IRF1 interferon regulatory factor 1 0.588031
DKKL1 dickkopf-like 1 0.584022
PRAMEF10 PRAME family member 10 0.581218
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.580417
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.577215
SYNE2 spectrin repeat containing, nuclear envelope 2 0.574017
ERBB4 erb-b2 receptor tyrosine kinase 4 0.572418
CDX1 caudal type homeobox 1 0.57082
IRF2 interferon regulatory factor 2 0.566828
TGFB1 transforming growth factor, beta 1 0.565631
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 0.564833
PXK PX domain containing serine/threonine kinase 0.562441
COX6C cytochrome c oxidase subunit VIc 0.55249
CTSL cathepsin L 0.552093
KLF4 Kruppel-like factor 4 (gut) 0.548914
ETF1 eukaryotic translation termination factor 1 0.545739
KDM6B lysine (K)-specific demethylase 6B 0.544152
PGF placental growth factor 0.541773
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.541377
LRP2 low density lipoprotein receptor-related protein 2 0.531879
FGFR1 fibroblast growth factor receptor 1 0.531484
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.529113
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.528323
EPHA1 EPH receptor A1 0.526744
GATA3 GATA binding protein 3 0.524377
MXD1 MAX dimerization protein 1 0.523194
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.520435
LIFR leukemia inhibitory factor receptor alpha 0.516497
SALL4 spalt-like transcription factor 4 0.514136
ODC1 ornithine decarboxylase 1 0.510206
ESRRB estrogen-related receptor beta 0.50942
SDC2 syndecan 2 0.509027
MAGT1 magnesium transporter 1 0.503533
ZSCAN4 zinc finger and SCAN domain containing 4 0.501965
KRT8 keratin 8, type II 0.500007
CARM1 coactivator-associated arginine methyltransferase 1 0.499615
DPPA5 developmental pluripotency associated 5 0.49844
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 0.494918
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 0.493354
GJA1 gap junction protein, alpha 1, 43kDa 0.491791
DSC2 desmocollin 2 0.488276
MSI2 musashi RNA-binding protein 2 0.487496
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.487106
IGF2 insulin-like growth factor 2 0.487106
IRF9 interferon regulatory factor 9 0.482038
FGF2 fibroblast growth factor 2 (basic) 0.481259
OCM2 oncomodulin 2 0.48048
ITGAV integrin, alpha V 0.479702
TUBA4A tubulin, alpha 4a 0.478923
CXXC1 CXXC finger protein 1 0.477756
OCM oncomodulin 0.476979
AQP3 aquaporin 3 (Gill blood group) 0.473869
H1FOO H1 histone family, member O, oocyte-specific 0.473869
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.47348
NRG4 neuregulin 4 0.473092
ISM1 isthmin 1, angiogenesis inhibitor 0.471927
ALPPL2 alkaline phosphatase, placental-like 2 0.471539
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.469599
MUC1 mucin 1, cell surface associated 0.464948
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.464561
NLRP4 NLR family, pyrin domain containing 4 0.461078
HLA-G major histocompatibility complex, class I, G 0.458759
CTBS chitobiase, di-N-acetyl- 0.452969
EZR ezrin 0.445268
RLIM ring finger protein, LIM domain interacting 0.445268
CFC1 cripto, FRL-1, cryptic family 1 0.441426
ALPL alkaline phosphatase, liver/bone/kidney 0.438739
FGF10 fibroblast growth factor 10 0.437972
ALPP alkaline phosphatase, placental 0.437972
TGFB3 transforming growth factor, beta 3 0.435672
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.435289
LPAR3 lysophosphatidic acid receptor 3 0.434523
CUL4B cullin 4B 0.432608
SOX15 SRY (sex determining region Y)-box 15 0.43146
ESR1 estrogen receptor 1 0.428783
GBP2 guanylate binding protein 2, interferon-inducible 0.428783
FOXJ2 forkhead box J2 0.423436
STPG1 sperm-tail PG-rich repeat containing 1 0.422673
SNAI2 snail family zinc finger 2 0.421148
ISG20 interferon stimulated exonuclease gene 20kDa 0.419623
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.419623
TET2 tet methylcytosine dioxygenase 2 0.41848
RYBP RING1 and YY1 binding protein 0.415814
GTF2IRD1 GTF2I repeat domain containing 1 0.412771
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.409351
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.407832
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.406315
BAX BCL2-associated X protein 0.404039
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.400628
FGF5 fibroblast growth factor 5 0.399492
PRICKLE1 prickle homolog 1 (Drosophila) 0.3976
GDF9 growth differentiation factor 9 0.394576
HOXD8 homeobox D8 0.392686
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.38665
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.385896
MAP3K10 mitogen-activated protein kinase kinase kinase 10 0.383637
DSC3 desmocollin 3 0.38326
RPL4 ribosomal protein L4 0.38326
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.378372
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.377621
AQP8 aquaporin 8 0.376119
HOXB7 homeobox B7 0.371619
CST3 cystatin C 0.369747
IGFBP1 insulin-like growth factor binding protein 1 0.369373
SCYL1 SCY1-like 1 (S. cerevisiae) 0.368998
H2AFZ H2A histone family, member Z 0.367502
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.367129
JUP junction plakoglobin 0.366381
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.365633
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.364886
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.362646
RHOU ras homolog family member U 0.360036
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.359292
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.358546
IFNG interferon, gamma 0.352969
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.351485
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.350743
KLF5 Kruppel-like factor 5 (intestinal) 0.350743
KLF8 Kruppel-like factor 8 0.350001
CXCL14 chemokine (C-X-C motif) ligand 14 0.34926
GCH1 GTP cyclohydrolase 1 0.347408
DNTT DNA nucleotidylexotransferase 0.347038
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.340757
CLDN14 claudin 14 0.340019
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 0.338914
TBX3 T-box 3 0.338914
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 0.337808
STAT1 signal transducer and activator of transcription 1, 91kDa 0.337072
LATS1 large tumor suppressor kinase 1 0.336336
IQGAP1 IQ motif containing GTPase activating protein 1 0.335968
FOXD3 forkhead box D3 0.334498
TUBA1C tubulin, alpha 1c 0.333763
EFNA1 ephrin-A1 0.333028
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.330094
TUBB2A tubulin, beta 2A class IIa 0.328628
SRY sex determining region Y 0.32753
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.327164
SETD7 SET domain containing (lysine methyltransferase) 7 0.325701
PRDM14 PR domain containing 14 0.325335
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.324239
HIST2H3C histone cluster 2, H3c 0.322414
HIST2H3A histone cluster 2, H3a 0.322414
HIST2H3D histone cluster 2, H3d 0.322414
MUC15 mucin 15, cell surface associated 0.320956
NLRP5 NLR family, pyrin domain containing 5 0.320591
ZNF35 zinc finger protein 35 0.316951
F11R F11 receptor 0.316951
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.315498
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.315135
EREG epiregulin 0.314409
FST follistatin 0.314046
ITGB8 integrin, beta 8 0.31332
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.312957
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.312232
LAMB2 laminin, beta 2 (laminin S) 0.311507
ST5 suppression of tumorigenicity 5 0.311145
LPAR1 lysophosphatidic acid receptor 1 0.311145
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.310783
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.309335
LGALS1 lectin, galactoside-binding, soluble, 1 0.308251
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.305722
ACTG1 actin gamma 1 0.305361
SCRIB scribbled planar cell polarity protein 0.303198
ALB albumin 0.303198
INS insulin 0.302478
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.302118
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.298524
HOXA10 homeobox A10 0.297806
CBX3 chromobox homolog 3 0.292793
TSPO translocator protein (18kDa) 0.292079
RAB13 RAB13, member RAS oncogene family 0.291365
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.290652
RPTOR regulatory associated protein of MTOR, complex 1 0.286026
NRG3 neuregulin 3 0.284607
SEBOX SEBOX homeobox 0.284607
TRIM27 tripartite motif containing 27 0.283545
SLC38A4 solute carrier family 38, member 4 0.282837
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.28213
GHSR growth hormone secretagogue receptor 0.281423
DICER1 dicer 1, ribonuclease type III 0.28107
TUBB tubulin, beta class I 0.280012
IFI27 interferon, alpha-inducible protein 27 0.278603
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.2779
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.277549
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 0.277197
NRG2 neuregulin 2 0.274744
BMP10 bone morphogenetic protein 10 0.273346
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.272997
GLB1 galactosidase, beta 1 0.272649
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.270214
ESX1 ESX homeobox 1 0.269174
CTSZ cathepsin Z 0.269174
TCF4 transcription factor 4 0.268482
ASXL1 additional sex combs like transcriptional regulator 1 0.268137
SFN stratifin 0.266757
DTX1 deltex 1, E3 ubiquitin ligase 0.266069
DLL3 delta-like 3 (Drosophila) 0.266069
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.264011
TDGF1 teratocarcinoma-derived growth factor 1 0.264011
CUL4A cullin 4A 0.262645
PRKCZ protein kinase C, zeta 0.262304
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.262304
FGFBP1 fibroblast growth factor binding protein 1 0.261964
TTK TTK protein kinase 0.259254
ATP11A ATPase, class VI, type 11A 0.256902
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.256234
CD44 CD44 molecule (Indian blood group) 0.2559
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.254902
HOXB6 homeobox B6 0.253908
FGF1 fibroblast growth factor 1 (acidic) 0.253248
UTF1 undifferentiated embryonic cell transcription factor 1 0.245175
FKBP4 FK506 binding protein 4, 59kDa 0.244232
NOBOX NOBOX oogenesis homeobox 0.244232
TBCE tubulin folding cofactor E 0.242983
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.242363
ACTB actin, beta 0.238108
DSG1 desmoglein 1 0.238108
IFIH1 interferon induced with helicase C domain 1 0.23781
VCL vinculin 0.23781
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.23604
IL6ST interleukin 6 signal transducer 0.234878
MTNR1A melatonin receptor 1A 0.233731
SIN3A SIN3 transcription regulator family member A 0.23011
MIR93 microRNA 93 0.229839
PORCN porcupine homolog (Drosophila) 0.229299
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.228764
HDAC1 histone deacetylase 1 0.228764
CLDN1 claudin 1 0.227186
BMPR1A bone morphogenetic protein receptor, type IA 0.227186
MTNR1B melatonin receptor 1B 0.226667
EGFL7 EGF-like-domain, multiple 7 0.226411
IGF1R insulin-like growth factor 1 receptor 0.226155
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.225647
CDC25A cell division cycle 25A 0.223906
WNT3A wingless-type MMTV integration site family, member 3A 0.223177
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.222224
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.219485
POU2F1 POU class 2 homeobox 1 0.219047
PRMT2 protein arginine methyltransferase 2 0.218398
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.216325
TET1 tet methylcytosine dioxygenase 1 0.215147
GTF2I general transcription factor IIi 0.214576
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 0.214202
TBP TATA box binding protein 0.213291
TLN1 talin 1 0.213112
ACVR2B activin A receptor, type IIB 0.212413