trophoblast Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A thin layer of ectoderm that forms the wall of many mammalian blastulas and functions in the nutrition and implantation of the embryo. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001079)
Similar Terms
Downloads & Tools

Genes

359 genes co-occuring with the biological term trophoblast in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE2 angiotensin I converting enzyme 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ACVR2A activin A receptor, type IIA
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADM2 adrenomedullin 2
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATG9B autophagy related 9B
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BMP4 bone morphogenetic protein 4
BOK BCL2-related ovarian killer
C19ORF33 chromosome 19 open reading frame 33
C1QBP complement component 1, q subcomponent binding protein
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C6 complement component 6
CALB1 calbindin 1, 28kDa
CALR calreticulin
CAPN1 calpain 1, (mu/I) large subunit
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL14 chemokine (C-C motif) ligand 14
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1D CD1d molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD274 CD274 molecule
CD276 CD276 molecule
CD44 CD44 molecule (Indian blood group)
CD82 CD82 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CGA glycoprotein hormones, alpha polypeptide
CGB chorionic gonadotropin, beta polypeptide
CHM choroideremia (Rab escort protein 1)
CLEC4M C-type lectin domain family 4, member M
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CRABP2 cellular retinoic acid binding protein 2
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRISP3 cysteine-rich secretory protein 3
CSNK1D casein kinase 1, delta
CSPG4 chondroitin sulfate proteoglycan 4
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CUL1 cullin 1
CUL7 cullin 7
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DLX3 distal-less homeobox 3
DPP4 dipeptidyl-peptidase 4
EBI3 Epstein-Barr virus induced 3
EDN1 endothelin 1
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EIF4E eukaryotic translation initiation factor 4E
ENG endoglin
EOMES eomesodermin
EPAS1 endothelial PAS domain protein 1
EPHB4 EPH receptor B4
EPO erythropoietin
ERVFRD-1 endogenous retrovirus group FRD, member 1
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRG estrogen-related receptor gamma
ESX1 ESX homeobox 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLN5 fibulin 5
FBXW8 F-box and WD repeat domain containing 8
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZD5 frizzled class receptor 5
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GCM1 glial cells missing homolog 1 (Drosophila)
GDF15 growth differentiation factor 15
GH2 growth hormone 2
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GPR182 G protein-coupled receptor 182
GRN granulin
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HBEGF heparin-binding EGF-like growth factor
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPSE heparanase
HRH1 histamine receptor H1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
HTRA4 HtrA serine peptidase 4
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL10 interleukin 10
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IL12A interleukin 12A
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL1B interleukin 1, beta
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INSL4 insulin-like 4 (placenta)
ISCU iron-sulfur cluster assembly enzyme
ITGA1 integrin, alpha 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KISS1 KiSS-1 metastasis-suppressor
KLF8 Kruppel-like factor 8
KLRK1 killer cell lectin-like receptor subfamily K, member 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LIF leukemia inhibitory factor
LIN28A lin-28 homolog A (C. elegans)
LNPEP leucyl/cystinyl aminopeptidase
LVRN laeverin
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MET MET proto-oncogene, receptor tyrosine kinase
MFSD2A major facilitator superfamily domain containing 2A
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIR106A microRNA 106a
MIR125B1 microRNA 125b-1
MIR144 microRNA 144
MIR17HG miR-17-92 cluster host gene
MIR18A microRNA 18a
MIR195 microRNA 195
MIR210 microRNA 210
MIR29B1 microRNA 29b-1
MIR363 microRNA 363
MIR378A microRNA 378a
MIR675 microRNA 675
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP26 matrix metallopeptidase 26
MMP9 matrix metallopeptidase 9
MSTN myostatin
MTA1 metastasis associated 1
MTA3 metastasis associated 1 family, member 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC15 mucin 15, cell surface associated
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAP1L4 nucleosome assembly protein 1-like 4
NEUROD1 neuronal differentiation 1
NEUROD2 neuronal differentiation 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP7 NLR family, pyrin domain containing 7
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NODAL nodal growth differentiation factor
NOMO1 NODAL modulator 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOV nephroblastoma overexpressed
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRP1 neuropilin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSBPL5 oxysterol binding protein-like 5
P4HB prolyl 4-hydroxylase, beta polypeptide
PAEP progestagen-associated endometrial protein
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARD6A par-6 family cell polarity regulator alpha
PDLIM1 PDZ and LIM domain 1
PGF placental growth factor
PIBF1 progesterone immunomodulatory binding factor 1
PLAC1 placenta-specific 1
PLAU plasminogen activator, urokinase
PLIN2 perilipin 2
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRL prolactin
PRLR prolactin receptor
PROK1 prokineticin 1
PRSS8 protease, serine, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTK2 protein tyrosine kinase 2
PTX3 pentraxin 3, long
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RETN resistin
RHOA ras homolog family member A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPSA ribosomal protein SA
RXRA retinoid X receptor, alpha
S1PR1 sphingosine-1-phosphate receptor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SELL selectin L
SFRP4 secreted frizzled-related protein 4
SHBG sex hormone-binding globulin
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI1 snail family zinc finger 1
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY2 sprouty homolog 2 (Drosophila)
SST somatostatin
SSTR2 somatostatin receptor 2
STARD7 StAR-related lipid transfer (START) domain containing 7
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STMN1 stathmin 1
STOX1 storkhead box 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR3 transforming growth factor, beta receptor III
TGIF1 TGFB-induced factor homeobox 1
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TP53 tumor protein p53
TP63 tumor protein p63
TPBG trophoblast glycoprotein
TPM4 tropomyosin 4
TRO trophinin
TSLP thymic stromal lymphopoietin
TTPA tocopherol (alpha) transfer protein
TTR transthyretin
UCN urocortin
UCN2 urocortin 2
UCN3 urocortin 3
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAQP4 YWHAQ pseudogene 4
YY1 YY1 transcription factor