tropicamide-3619 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tropicamide-3619 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AFF2 AF4/FMR2 family, member 2
ALOX5 arachidonate 5-lipoxygenase
ANP32A-IT1 ANP32A intronic transcript 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATN1 atrophin 1
ATXN7L1 ataxin 7-like 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAPN6 calpain 6
CAV3 caveolin 3
CCL19 chemokine (C-C motif) ligand 19
CD22 CD22 molecule
CDC14A cell division cycle 14A
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
COL19A1 collagen, type XIX, alpha 1
COL7A1 collagen, type VII, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
DEFA4 defensin, alpha 4, corticostatin
DMBT1 deleted in malignant brain tumors 1
DRD1 dopamine receptor D1
DUX1 double homeobox 1
DZIP1 DAZ interacting zinc finger protein 1
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
ERCC2 excision repair cross-complementation group 2
FLOT1 flotillin 1
FOSL2 FOS-like antigen 2
FOXA2 forkhead box A2
GDF2 growth differentiation factor 2
GJA8 gap junction protein, alpha 8, 50kDa
GPR52 G protein-coupled receptor 52
GRM1 glutamate receptor, metabotropic 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICA1 islet cell autoantigen 1, 69kDa
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL11RA interleukin 11 receptor, alpha
IL1RN interleukin 1 receptor antagonist
KCTD12 potassium channel tetramerization domain containing 12
KIAA0226L KIAA0226-like
KLHL29 kelch-like family member 29
LDB3 LIM domain binding 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMTK2 lemur tyrosine kinase 2
LMX1B LIM homeobox transcription factor 1, beta
LRRK1 leucine-rich repeat kinase 1
MAB21L1 mab-21-like 1 (C. elegans)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPT microtubule-associated protein tau
MKL1 megakaryoblastic leukemia (translocation) 1
NPY2R neuropeptide Y receptor Y2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR1A1 olfactory receptor, family 1, subfamily A, member 1
PAX1 paired box 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH1 protocadherin 1
PDE4DIP phosphodiesterase 4D interacting protein
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGR polymeric immunoglobulin receptor
PLIN2 perilipin 2
PLLP plasmolipin
PSCA prostate stem cell antigen
RAB3B RAB3B, member RAS oncogene family
RASIP1 Ras interacting protein 1
RHO rhodopsin
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPS4Y1 ribosomal protein S4, Y-linked 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIM2 single-minded family bHLH transcription factor 2
SIT1 signaling threshold regulating transmembrane adaptor 1
SLA Src-like-adaptor
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNRPN small nuclear ribonucleoprotein polypeptide N
SNX1 sorting nexin 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRCAP Snf2-related CREBBP activator protein
SYCE1L synaptonemal complex central element protein 1-like
TACR3 tachykinin receptor 3
TDRD3 tudor domain containing 3
TEX15 testis expressed 15
TTLL4 tubulin tyrosine ligase-like family member 4
WDR62 WD repeat domain 62
ZFP64 ZFP64 zinc finger protein
ZNF224 zinc finger protein 224
ZNF230 zinc finger protein 230
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BIRC7 baculoviral IAP repeat containing 7
BMP10 bone morphogenetic protein 10
C11ORF21 chromosome 11 open reading frame 21
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
C7ORF43 chromosome 7 open reading frame 43
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC68 coiled-coil domain containing 68
CD3D CD3d molecule, delta (CD3-TCR complex)
CEND1 cell cycle exit and neuronal differentiation 1
CENPO centromere protein O
CFAP44 cilia and flagella associated protein 44
CFAP70 cilia and flagella associated protein 70
CNR2 cannabinoid receptor 2 (macrophage)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CXXC4 CXXC finger protein 4
DEPDC5 DEP domain containing 5
DIO1 deiodinase, iodothyronine, type I
DOK5 docking protein 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHB3 EPH receptor B3
ERN1 endoplasmic reticulum to nucleus signaling 1
EXOC6B exocyst complex component 6B
FADS2 fatty acid desaturase 2
FAM212B family with sequence similarity 212, member B
FBXW12 F-box and WD repeat domain containing 12
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
GAMT guanidinoacetate N-methyltransferase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR21 G protein-coupled receptor 21
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HIST1H4F histone cluster 1, H4f
HOXC5 homeobox C5
HP1BP3 heterochromatin protein 1, binding protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
INPP5J inositol polyphosphate-5-phosphatase J
IRF6 interferon regulatory factor 6
ITPKB inositol-trisphosphate 3-kinase B
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF3 Kruppel-like factor 3 (basic)
KRT9 keratin 9, type I
LIME1 Lck interacting transmembrane adaptor 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LOXL3 lysyl oxidase-like 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOB3B MOB kinase activator 3B
MTA2 metastasis associated 1 family, member 2
NBEAL2 neurobeachin-like 2
NCALD neurocalcin delta
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PGR progesterone receptor
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP5C protein phosphatase 5, catalytic subunit
PSKH1 protein serine kinase H1
RNF43 ring finger protein 43
RPL10L ribosomal protein L10-like
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SGCE sarcoglycan, epsilon
SH2B3 SH2B adaptor protein 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLN sarcolipin
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STON1 stonin 1
TARP TCR gamma alternate reading frame protein
TBKBP1 TBK1 binding protein 1
TGFBR3 transforming growth factor, beta receptor III
THRAP3 thyroid hormone receptor associated protein 3
TLR2 toll-like receptor 2
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSC22D4 TSC22 domain family, member 4
TUBA4B tubulin, alpha 4b
VASH1 vasohibin 1
VAX2 ventral anterior homeobox 2
VN1R1 vomeronasal 1 receptor 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZFP37 ZFP37 zinc finger protein
ZIC3 Zic family member 3
ZNF34 zinc finger protein 34
ZNF480 zinc finger protein 480
ZNF510 zinc finger protein 510
ZNF665 zinc finger protein 665