tropicamide-3722 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tropicamide-3722 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACAN aggrecan
APOL2 apolipoprotein L, 2
ARC activity-regulated cytoskeleton-associated protein
ARL4D ADP-ribosylation factor-like 4D
ARTN artemin
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BTN3A1 butyrophilin, subfamily 3, member A1
C14ORF79 chromosome 14 open reading frame 79
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CD82 CD82 molecule
CDK18 cyclin-dependent kinase 18
CDK20 cyclin-dependent kinase 20
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CEL carboxyl ester lipase
COL1A2 collagen, type I, alpha 2
CREM cAMP responsive element modulator
CST4 cystatin S
DMBT1 deleted in malignant brain tumors 1
DMWD dystrophia myotonica, WD repeat containing
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
FAM149B1 family with sequence similarity 149, member B1
FLJ22184
FRZB frizzled-related protein
GAB1 GRB2-associated binding protein 1
GFER growth factor, augmenter of liver regeneration
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GK2 glycerol kinase 2
GLYAT glycine-N-acyltransferase
GPR15 G protein-coupled receptor 15
GPR19 G protein-coupled receptor 19
GSTA3 glutathione S-transferase alpha 3
HCG4B HLA complex group 4B (non-protein coding)
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIST1H3A histone cluster 1, H3a
HRG histidine-rich glycoprotein
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INO80D INO80 complex subunit D
KIF25 kinesin family member 25
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KLRC4 killer cell lectin-like receptor subfamily C, member 4
LIMK2 LIM domain kinase 2
LMNA lamin A/C
LOC100294391 uncharacterized LOC100294391
LTBP4 latent transforming growth factor beta binding protein 4
MAP3K13 mitogen-activated protein kinase kinase kinase 13
NEO1 neogenin 1
NNAT neuronatin
NOV nephroblastoma overexpressed
NPFF neuropeptide FF-amide peptide precursor
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRIP3 nuclear receptor interacting protein 3
NSUN6 NOP2/Sun domain family, member 6
ORAI2 ORAI calcium release-activated calcium modulator 2
PALM paralemmin
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDLIM4 PDZ and LIM domain 4
PIGR polymeric immunoglobulin receptor
PKNOX2 PBX/knotted 1 homeobox 2
PLXND1 plexin D1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POU2F2 POU class 2 homeobox 2
POU5F1B POU class 5 homeobox 1B
PQLC2 PQ loop repeat containing 2
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
RAD51 RAD51 recombinase
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGS4 regulator of G-protein signaling 4
RIMS3 regulating synaptic membrane exocytosis 3
RSU1 Ras suppressor protein 1
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SIRT4 sirtuin 4
SMAD6 SMAD family member 6
SPRR1A small proline-rich protein 1A
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAB2 stabilin 2
SYT12 synaptotagmin XII
SYT2 synaptotagmin II
TAOK2 TAO kinase 2
TBL1Y transducin (beta)-like 1, Y-linked
TESC tescalcin
TK2 thymidine kinase 2, mitochondrial
TLE2 transducin-like enhancer of split 2
TRAPPC9 trafficking protein particle complex 9
TUBA3C tubulin, alpha 3c
UNC13A unc-13 homolog A (C. elegans)
USP2 ubiquitin specific peptidase 2
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNT3 wingless-type MMTV integration site family, member 3
XAF1 XIAP associated factor 1
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AHSG alpha-2-HS-glycoprotein
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AK5 adenylate kinase 5
ANKH ANKH inorganic pyrophosphate transport regulator
ANXA2P1 annexin A2 pseudogene 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMCX4 armadillo repeat containing, X-linked 4
ATAT1 alpha tubulin acetyltransferase 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BTF3P12 basic transcription factor 3 pseudogene 12
C3 complement component 3
CARD8 caspase recruitment domain family, member 8
CCDC186 coiled-coil domain containing 186
CCDC7 coiled-coil domain containing 7
CCDC71 coiled-coil domain containing 71
CDC37L1 cell division cycle 37-like 1
CHST10 carbohydrate sulfotransferase 10
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNPY4 canopy FGF signaling regulator 4
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYB5R2 cytochrome b5 reductase 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DIO3 deiodinase, iodothyronine, type III
DYM dymeclin
ELSPBP1 epididymal sperm binding protein 1
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FAM222B family with sequence similarity 222, member B
FKRP fukutin related protein
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HLA-DMB major histocompatibility complex, class II, DM beta
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IPO8 importin 8
IPP intracisternal A particle-promoted polypeptide
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL29 kelch-like family member 29
KRT4 keratin 4, type II
LMTK2 lemur tyrosine kinase 2
LPAR3 lysophosphatidic acid receptor 3
LPPR1 lipid phosphate phosphatase-related protein type 1
MAP2 microtubule-associated protein 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MED31 mediator complex subunit 31
MRPL44 mitochondrial ribosomal protein L44
MTERF4 mitochondrial transcription termination factor 4
NARFL nuclear prelamin A recognition factor-like
NELL2 NEL-like 2 (chicken)
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
NPHP1 nephronophthisis 1 (juvenile)
NPIPB3 nuclear pore complex interacting protein family, member B3
ODF2 outer dense fiber of sperm tails 2
OSMR oncostatin M receptor
PAX9 paired box 9
PC pyruvate carboxylase
PCBP3 poly(rC) binding protein 3
PLXNA3 plexin A3
PRF1 perforin 1 (pore forming protein)
PRR4 proline rich 4 (lacrimal)
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SAYSD1 SAYSVFN motif domain containing 1
SENP7 SUMO1/sentrin specific peptidase 7
SERGEF secretion regulating guanine nucleotide exchange factor
SLC25A40 solute carrier family 25, member 40
SUSD4 sushi domain containing 4
TBC1D2 TBC1 domain family, member 2
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TESPA1 thymocyte expressed, positive selection associated 1
TEX15 testis expressed 15
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TMEM40 transmembrane protein 40
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAC T cell receptor alpha constant
TRIM45 tripartite motif containing 45
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TWISTNB TWIST neighbor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGLL3 vestigial-like family member 3
VLDLR very low density lipoprotein receptor
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675
ZNF74 zinc finger protein 74