tropicamide-4744 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tropicamide-4744 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACRV1 acrosomal vesicle protein 1
ADAM29 ADAM metallopeptidase domain 29
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHNAK2 AHNAK nucleoprotein 2
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOM apolipoprotein M
ASIC1 acid sensing (proton gated) ion channel 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALML5 calmodulin-like 5
CCDC64 coiled-coil domain containing 64
CD28 CD28 molecule
CDC25C cell division cycle 25C
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFAP45 cilia and flagella associated protein 45
COL13A1 collagen, type XIII, alpha 1
COL1A1 collagen, type I, alpha 1
CRY2 cryptochrome circadian clock 2
CRYGC crystallin, gamma C
CSNK1G1 casein kinase 1, gamma 1
CTBP2 C-terminal binding protein 2
DCX doublecortin
DTNA dystrobrevin, alpha
EMID1 EMI domain containing 1
EMP1 epithelial membrane protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVA1B eva-1 homolog B (C. elegans)
FAM105A family with sequence similarity 105, member A
FAM63B family with sequence similarity 63, member B
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOXI1 forkhead box I1
FRMD1 FERM domain containing 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GPATCH4 G patch domain containing 4
GREB1L growth regulation by estrogen in breast cancer-like
GYG2 glycogenin 2
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ICOSLG inducible T-cell co-stimulator ligand
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLF9 Kruppel-like factor 9
KRT8 keratin 8, type II
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAPK7 mitogen-activated protein kinase 7
MTSS1L metastasis suppressor 1-like
MYT1 myelin transcription factor 1
NFX1 nuclear transcription factor, X-box binding 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OPCML opioid binding protein/cell adhesion molecule-like
OSGIN1 oxidative stress induced growth inhibitor 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCD1 phospholipase C, delta 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSCA prostate stem cell antigen
PTHLH parathyroid hormone-like hormone
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3B RAB3B, member RAS oncogene family
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS10 regulator of G-protein signaling 10
RHBG Rh family, B glycoprotein (gene/pseudogene)
SATB2 SATB homeobox 2
SERHL2 serine hydrolase-like 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SNCAIP synuclein, alpha interacting protein
SORBS2 sorbin and SH3 domain containing 2
SP100 SP100 nuclear antigen
SRCAP Snf2-related CREBBP activator protein
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT12 synaptotagmin XII
TBC1D2 TBC1 domain family, member 2
THBS4 thrombospondin 4
TJAP1 tight junction associated protein 1 (peripheral)
TLDC1 TBC/LysM-associated domain containing 1
TP53I11 tumor protein p53 inducible protein 11
TTLL4 tubulin tyrosine ligase-like family member 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VCX2 variable charge, X-linked 2
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WIPI2 WD repeat domain, phosphoinositide interacting 2
XYLB xylulokinase homolog (H. influenzae)
ZNF362 zinc finger protein 362
ZNF589 zinc finger protein 589
ZNF702P zinc finger protein 702, pseudogene
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
C11ORF30 chromosome 11 open reading frame 30
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
CAPN15 calpain 15
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD8A CD8a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK20 cyclin-dependent kinase 20
CEMIP cell migration inducing protein, hyaluronan binding
CENPO centromere protein O
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN6 chloride channel, voltage-sensitive 6
CXADR coxsackie virus and adenovirus receptor
DGKE diacylglycerol kinase, epsilon 64kDa
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDAR ectodysplasin A receptor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELSPBP1 epididymal sperm binding protein 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHX2 epoxide hydrolase 2, cytoplasmic
F2R coagulation factor II (thrombin) receptor
FAM110B family with sequence similarity 110, member B
FAM155A family with sequence similarity 155, member A
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRA1 glycine receptor, alpha 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HMOX1 heme oxygenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A2 leucine rich repeat containing 37, member A2
LTBP2 latent transforming growth factor beta binding protein 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTA2 metastasis associated 1 family, member 2
MYL5 myosin, light chain 5, regulatory
MYO1F myosin IF
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
NPFFR1 neuropeptide FF receptor 1
ONECUT1 one cut homeobox 1
PCDHA5 protocadherin alpha 5
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGR progesterone receptor
PRAF2 PRA1 domain family, member 2
PRSS53 protease, serine, 53
RAB36 RAB36, member RAS oncogene family
RAI2 retinoic acid induced 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL3 ret finger protein-like 3
RPGR retinitis pigmentosa GTPase regulator
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
STON1 stonin 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TFF2 trefoil factor 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USP18 ubiquitin specific peptidase 18
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB33 zinc finger and BTB domain containing 33
ZBTB44 zinc finger and BTB domain containing 44
ZNF423 zinc finger protein 423