| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the tropine-6264 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACVR1B | activin A receptor, type IB |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATG3 | autophagy related 3 |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| BMP4 | bone morphogenetic protein 4 |
| CALHM2 | calcium homeostasis modulator 2 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDH5 | cadherin 5, type 2 (vascular endothelium) |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPS7B | COP9 signalosome subunit 7B |
| DAPK3 | death-associated protein kinase 3 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| EPS8L1 | EPS8-like 1 |
| FRMD4B | FERM domain containing 4B |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GON4L | gon-4-like (C. elegans) |
| GRIP2 | glutamate receptor interacting protein 2 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IDS | iduronate 2-sulfatase |
| IGHM | immunoglobulin heavy constant mu |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL22 | interleukin 22 |
| IL4R | interleukin 4 receptor |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL24 | kelch-like family member 24 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KSR1 | kinase suppressor of ras 1 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMBR1L | limb development membrane protein 1-like |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MCOLN3 | mucolipin 3 |
| MED6 | mediator complex subunit 6 |
| MST1L | macrophage stimulating 1-like |
| MYL5 | myosin, light chain 5, regulatory |
| NF2 | neurofibromin 2 (merlin) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OGFR | opioid growth factor receptor |
| ONECUT2 | one cut homeobox 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PENK | proenkephalin |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G3 | phospholipase A2, group III |
| PLTP | phospholipid transfer protein |
| PLXNA1 | plexin A1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| QKI | QKI, KH domain containing, RNA binding |
| RBM19 | RNA binding motif protein 19 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RFXAP | regulatory factor X-associated protein |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAFB2 | scaffold attachment factor B2 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SP100 | SP100 nuclear antigen |
| SPPL2B | signal peptide peptidase like 2B |
| STAG3 | stromal antigen 3 |
| STK38L | serine/threonine kinase 38 like |
| TBX6 | T-box 6 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM29 | tripartite motif containing 29 |
| TRIM5 | tripartite motif containing 5 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| UBE3A | ubiquitin protein ligase E3A |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VAX2 | ventral anterior homeobox 2 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| WDR25 | WD repeat domain 25 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AGO1 | argonaute RISC catalytic component 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKRD28 | ankyrin repeat domain 28 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| CAPN15 | calpain 15 |
| CBX4 | chromobox homolog 4 |
| CCDC88C | coiled-coil domain containing 88C |
| CDK3 | cyclin-dependent kinase 3 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFD | complement factor D (adipsin) |
| CHMP7 | charged multivesicular body protein 7 |
| COBL | cordon-bleu WH2 repeat protein |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRYL1 | crystallin, lambda 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYBA | cytochrome b-245, alpha polypeptide |
| DBR1 | debranching RNA lariats 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNM1 | dynamin 1 |
| DNMBP | dynamin binding protein |
| DOCK1 | dedicator of cytokinesis 1 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EXOC5 | exocyst complex component 5 |
| FAM192A | family with sequence similarity 192, member A |
| FAM222B | family with sequence similarity 222, member B |
| FANCF | Fanconi anemia, complementation group F |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FBXO46 | F-box protein 46 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FPGS | folylpolyglutamate synthase |
| GRAMD4 | GRAM domain containing 4 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HS1BP3 | HCLS1 binding protein 3 |
| HYOU1 | hypoxia up-regulated 1 |
| IRF6 | interferon regulatory factor 6 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0556 | KIAA0556 |
| KIAA0895 | KIAA0895 |
| KIF14 | kinesin family member 14 |
| KIZ | kizuna centrosomal protein |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED15 | mediator complex subunit 15 |
| MED22 | mediator complex subunit 22 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| POLH | polymerase (DNA directed), eta |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PQLC1 | PQ loop repeat containing 1 |
| PROCR | protein C receptor, endothelial |
| REEP4 | receptor accessory protein 4 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RNF25 | ring finger protein 25 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SECISBP2 | SECIS binding protein 2 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SNAI2 | snail family zinc finger 2 |
| SUSD6 | sushi domain containing 6 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCTA | T-cell leukemia translocation altered |
| THYN1 | thymocyte nuclear protein 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRAPPC13 | trafficking protein particle complex 13 |
| TSPAN1 | tetraspanin 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF226 | zinc finger protein 226 |
| ZNF271P | zinc finger protein 271, pseudogene |
| ZNF623 | zinc finger protein 623 |
| ZNF7 | zinc finger protein 7 |