trpv1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description transient receptor potential cation channel, subfamily V, member 1|Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7442)
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Genes

43 genes co-occuring with the biological term trpv1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AKAP5 A kinase (PRKA) anchor protein 5
BDKRB1 bradykinin receptor B1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CHGA chromogranin A
CLDN3 claudin 3
CLDN4 claudin 4
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
IGF1 insulin-like growth factor 1 (somatomedin C)
IL6 interleukin 6
MAPK8 mitogen-activated protein kinase 8
MIR325 microRNA 325
MMP1 matrix metallopeptidase 1
MRGPRX1 MAS-related GPR, member X1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
OPRM1 opioid receptor, mu 1
OXTR oxytocin receptor
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PVALB parvalbumin
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SMAD2 SMAD family member 2
TGFB1 transforming growth factor, beta 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSLP thymic stromal lymphopoietin