trpv6 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description transient receptor potential cation channel, subfamily V, member 6|This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015] (NCBI Entrez Gene Database, 55503)
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Genes

19 genes co-occuring with the biological term trpv6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CLDN3 claudin 3
CLDN4 claudin 4
ESR1 estrogen receptor 1
NUMB numb homolog (Drosophila)
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIKFYVE phosphoinositide kinase, FYVE finger containing
PPIB peptidylprolyl isomerase B (cyclophilin B)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RGS2 regulator of G-protein signaling 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNK3 WNK lysine deficient protein kinase 3
WNK4 WNK lysine deficient protein kinase 4