transformation/transcription domain-associated protein|This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 8295)
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13 genes co-occuring with the biological term trrap in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.