ttf1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description transcription termination factor, RNA polymerase I|This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression. [provided by RefSeq, Apr 2011] (NCBI Entrez Gene Database, 7270)
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Genes

44 genes co-occuring with the biological term ttf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ALK anaplastic lymphoma receptor tyrosine kinase
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHGA chromogranin A
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
ETV5 ets variant 5
FN1 fibronectin 1
FOXA2 forkhead box A2
GATA3 GATA binding protein 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
LGALS3 lectin, galactoside-binding, soluble, 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR365A microRNA 365a
MUC16 mucin 16, cell surface associated
NAPSA napsin A aspartic peptidase
NCAM1 neural cell adhesion molecule 1
NKX2-1 NK2 homeobox 1
NKX2-8 NK2 homeobox 8
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OCLN occludin
PARP2 poly (ADP-ribose) polymerase 2
PAX8 paired box 8
PAX9 paired box 9
POU3F2 POU class 3 homeobox 2
POU5F1 POU class 5 homeobox 1
PTTG1 pituitary tumor-transforming 1
SDC1 syndecan 1
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SMAD3 SMAD family member 3
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SYP synaptophysin
TG thyroglobulin
TNF tumor necrosis factor
TP63 tumor protein p63
TTF1 transcription termination factor, RNA polymerase I
VIM vimentin