tube closure Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. (Gene Ontology, GO_0060606)
External Link http://amigo.geneontology.org/amigo/term/GO:0060606
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Genes

30 genes participating in the tube closure biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
BBS4 Bardet-Biedl syndrome 4
BCL10 B-cell CLL/lymphoma 10
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
COBL cordon-bleu WH2 repeat protein
DEAF1 DEAF1 transcription factor
DLC1 DLC1 Rho GTPase activating protein
DVL2 dishevelled segment polarity protein 2
FOLR2 folate receptor 2 (fetal)
FUZ fuzzy planar cell polarity protein
GRHL2 grainyhead-like 2 (Drosophila)
GRHL3 grainyhead-like 3 (Drosophila)
IFT122 intraflagellar transport 122
LMO4 LIM domain only 4
LRP2 low density lipoprotein receptor-related protein 2
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
PAX2 paired box 2
PHACTR4 phosphatase and actin regulator 4
PLXNB2 plexin B2
PRICKLE1 prickle homolog 1 (Drosophila)
SCRIB scribbled planar cell polarity protein
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SKI SKI proto-oncogene
STIL SCL/TAL1 interrupting locus
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TSC2 tuberous sclerosis 2
VANGL2 VANGL planar cell polarity protein 2
VASP vasodilator-stimulated phosphoprotein