tubocurarine chloride-1738 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tubocurarine chloride-1738 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAM15 ADAM metallopeptidase domain 15
AFF1 AF4/FMR2 family, member 1
AKR1C1 aldo-keto reductase family 1, member C1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOM apolipoprotein M
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATG4B autophagy related 4B, cysteine peptidase
ATP10D ATPase, class V, type 10D
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
CADM3 cell adhesion molecule 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC64 coiled-coil domain containing 64
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD177 CD177 molecule
CD68 CD68 molecule
CDK6 cyclin-dependent kinase 6
CEP152 centrosomal protein 152kDa
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTNAP1 contactin associated protein 1
COL6A1 collagen, type VI, alpha 1
CRAT carnitine O-acetyltransferase
DLK2 delta-like 2 homolog (Drosophila)
EDRF1 erythroid differentiation regulatory factor 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM171A1 family with sequence similarity 171, member A1
FAM214B family with sequence similarity 214, member B
FES FES proto-oncogene, tyrosine kinase
FH fumarate hydratase
GBAP1 glucosidase, beta, acid pseudogene 1
GEMIN6 gem (nuclear organelle) associated protein 6
GFOD2 glucose-fructose oxidoreductase domain containing 2
GJD2 gap junction protein, delta 2, 36kDa
GLB1L2 galactosidase, beta 1-like 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPR182 G protein-coupled receptor 182
HAO2 hydroxyacid oxidase 2 (long chain)
HK2 hexokinase 2
HNF1A HNF1 homeobox A
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
HYI hydroxypyruvate isomerase (putative)
IGKV1D-13 immunoglobulin kappa variable 1D-13
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB5 integrin, beta 5
KAT8 K(lysine) acetyltransferase 8
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT18 keratin 18, type I
LARP7 La ribonucleoprotein domain family, member 7
LINC00312 long intergenic non-protein coding RNA 312
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAML3 mastermind-like 3 (Drosophila)
MARCKS myristoylated alanine-rich protein kinase C substrate
MB myoglobin
MCC mutated in colorectal cancers
MMP19 matrix metallopeptidase 19
MOB3B MOB kinase activator 3B
MPZL1 myelin protein zero-like 1
MYRF myelin regulatory factor
NIPAL2 NIPA-like domain containing 2
NOP16 NOP16 nucleolar protein
NOSIP nitric oxide synthase interacting protein
NTF3 neurotrophin 3
OR10H1 olfactory receptor, family 10, subfamily H, member 1
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PER1 period circadian clock 1
PIAS4 protein inhibitor of activated STAT, 4
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRY PTPN13-like, Y-linked
RANBP3 RAN binding protein 3
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAF4 SR-related CTD-associated factor 4
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SEZ6L seizure related 6 homolog (mouse)-like
SH2D1A SH2 domain containing 1A
SHB Src homology 2 domain containing adaptor protein B
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOD3 superoxide dismutase 3, extracellular
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SUGP1 SURP and G patch domain containing 1
TCTN1 tectonic family member 1
TFCP2L1 transcription factor CP2-like 1
TFE3 transcription factor binding to IGHM enhancer 3
THBS3 thrombospondin 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
UBE2O ubiquitin-conjugating enzyme E2O
YLPM1 YLP motif containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZC3H13 zinc finger CCCH-type containing 13

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ANKRD11 ankyrin repeat domain 11
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BANP BTG3 associated nuclear protein
BCOR BCL6 corepressor
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CD33 CD33 molecule
CDC7 cell division cycle 7
CETN2 centrin, EF-hand protein, 2
CLDN15 claudin 15
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COPS7B COP9 signalosome subunit 7B
CRY1 cryptochrome circadian clock 1
DERL2 derlin 2
DIXDC1 DIX domain containing 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPYD dihydropyrimidine dehydrogenase
EGR3 early growth response 3
FBXW4 F-box and WD repeat domain containing 4
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS2 GINS complex subunit 2 (Psf2 homolog)
GMIP GEM interacting protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR183 G protein-coupled receptor 183
HAT1 histone acetyltransferase 1
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
INO80D INO80 complex subunit D
KIAA1598
LAS1L LAS1-like (S. cerevisiae)
LMAN2L lectin, mannose-binding 2-like
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGOHB mago-nashi homolog B (Drosophila)
MBIP MAP3K12 binding inhibitory protein 1
MDN1 MDN1, midasin homolog (yeast)
MORC3 MORC family CW-type zinc finger 3
MPV17 MpV17 mitochondrial inner membrane protein
MRPL19 mitochondrial ribosomal protein L19
MT1HL1 metallothionein 1H-like 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NEU1 sialidase 1 (lysosomal sialidase)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOD1 nucleotide-binding oligomerization domain containing 1
NOTCH1 notch 1
NRBF2 nuclear receptor binding factor 2
NVL nuclear VCP-like
PAQR3 progestin and adipoQ receptor family member III
PARG poly (ADP-ribose) glycohydrolase
PCNXL4 pecanex-like 4 (Drosophila)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PNPLA6 patatin-like phospholipase domain containing 6
PNRC1 proline-rich nuclear receptor coactivator 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRPF19 pre-mRNA processing factor 19
PTBP2 polypyrimidine tract binding protein 2
RBM14 RNA binding motif protein 14
RFPL3 ret finger protein-like 3
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SEC61B Sec61 beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3GL1 SH3-domain GRB2-like 1
SLC2A4RG SLC2A4 regulator
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SNX17 sorting nexin 17
SNX6 sorting nexin 6
STK39 serine threonine kinase 39
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TARBP2 TAR (HIV-1) RNA binding protein 2
TMEM38B transmembrane protein 38B
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAPPC11 trafficking protein particle complex 11
TSPAN32 tetraspanin 32
TTI2 TELO2 interacting protein 2
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBAC1 UBA domain containing 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP24 ubiquitin specific peptidase 24
VCPKMT valosin containing protein lysine (K) methyltransferase
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XAF1 XIAP associated factor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF124 zinc finger protein 124
ZNF189 zinc finger protein 189
ZNF212 zinc finger protein 212
ZNF268 zinc finger protein 268
ZNF432 zinc finger protein 432
ZNF529 zinc finger protein 529