twist2 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	twist family bHLH transcription factor 2\|The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 117581)
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Genes

11 genes co-occuring with the biological term twist2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL10	interleukin 10
MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MIR138-1	microRNA 138-1
PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)
POSTN	periostin, osteoblast specific factor
RUNX2	runt-related transcription factor 2
SNIP1	Smad nuclear interacting protein 1
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
TWIST1	twist family bHLH transcription factor 1
TWIST2	twist family bHLH transcription factor 2