| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the tyloxapol-3074 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACVRL1 | activin A receptor type II-like 1 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| B9D1 | B9 protein domain 1 |
| BIN1 | bridging integrator 1 |
| CD248 | CD248 molecule, endosialin |
| CFAP45 | cilia and flagella associated protein 45 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL10A1 | collagen, type X, alpha 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CYB561 | cytochrome b561 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DLX4 | distal-less homeobox 4 |
| EFNA4 | ephrin-A4 |
| EGFR | epidermal growth factor receptor |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| ESR1 | estrogen receptor 1 |
| FAM155A | family with sequence similarity 155, member A |
| FAM76A | family with sequence similarity 76, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO40 | F-box protein 40 |
| FCAR | Fc fragment of IgA receptor |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FGF18 | fibroblast growth factor 18 |
| FGF4 | fibroblast growth factor 4 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GPC4 | glypican 4 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HABP4 | hyaluronan binding protein 4 |
| HDAC6 | histone deacetylase 6 |
| HOXC8 | homeobox C8 |
| HOXD11 | homeobox D11 |
| INO80D | INO80 complex subunit D |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0513 | KIAA0513 |
| KLC2 | kinesin light chain 2 |
| KRT85 | keratin 85, type II |
| LAMA4 | laminin, alpha 4 |
| LINC00474 | long intergenic non-protein coding RNA 474 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MB | myoglobin |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLXIPL | MLX interacting protein-like |
| MPZL1 | myelin protein zero-like 1 |
| MYCT1 | myc target 1 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO6 | myosin VI |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRCAM | neuronal cell adhesion molecule |
| NRF1 | nuclear respiratory factor 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PDE8B | phosphodiesterase 8B |
| PDPN | podoplanin |
| PLCE1 | phospholipase C, epsilon 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTMS | parathymosin |
| RAB40A | RAB40A, member RAS oncogene family |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RPL10 | ribosomal protein L10 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SH2D3A | SH2 domain containing 3A |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIX3 | SIX homeobox 3 |
| SLAMF8 | SLAM family member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMAD6 | SMAD family member 6 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPON1 | spondin 1, extracellular matrix protein |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAT | tyrosine aminotransferase |
| TCF3 | transcription factor 3 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TP53AIP1 | tumor protein p53 regulated apoptosis inducing protein 1 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADM | adrenomedullin |
| ANKRD40 | ankyrin repeat domain 40 |
| ARF5 | ADP-ribosylation factor 5 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| AZU1 | azurocidin 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CAPN15 | calpain 15 |
| CCNT1 | cyclin T1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL4A2 | collagen, type IV, alpha 2 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CTSG | cathepsin G |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DUSP2 | dual specificity phosphatase 2 |
| EMC9 | ER membrane protein complex subunit 9 |
| ENDOG | endonuclease G |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERCC2 | excision repair cross-complementation group 2 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| EXOSC1 | exosome component 1 |
| FAM57A | family with sequence similarity 57, member A |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FEM1C | fem-1 homolog c (C. elegans) |
| FGL1 | fibrinogen-like 1 |
| FHL3 | four and a half LIM domains 3 |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBP5 | FK506 binding protein 5 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GPR27 | G protein-coupled receptor 27 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4J | histone cluster 1, H4j |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRX5 | iroquois homeobox 5 |
| ITGA10 | integrin, alpha 10 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIF24 | kinesin family member 24 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGEH1 | melanoma antigen family H1 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MEFV | Mediterranean fever |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MTCP1 | mature T-cell proliferation 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PERP | PERP, TP53 apoptosis effector |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T |
| PLTP | phospholipid transfer protein |
| PRAF2 | PRA1 domain family, member 2 |
| PTAFR | platelet-activating factor receptor |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFXAP | regulatory factor X-associated protein |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIN1 | Ras and Rab interactor 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| S100A12 | S100 calcium binding protein A12 |
| SIRT6 | sirtuin 6 |
| SKI | SKI proto-oncogene |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| TCTA | T-cell leukemia translocation altered |
| TEC | tec protein tyrosine kinase |
| TMC5 | transmembrane channel-like 5 |
| TMEM246 | transmembrane protein 246 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN14 | tetraspanin 14 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC26 | tetratricopeptide repeat domain 26 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF215 | zinc finger protein 215 |
| ZNF324 | zinc finger protein 324 |
| ZNF426 | zinc finger protein 426 |
| ZNF493 | zinc finger protein 493 |
