| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tyloxapol-4611 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABHD6 | abhydrolase domain containing 6 |
| APOL1 | apolipoprotein L, 1 |
| BEX1 | brain expressed, X-linked 1 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CD1C | CD1c molecule |
| CD4 | CD4 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CEMP1 | cementum protein 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRH | corticotropin releasing hormone |
| DICER1 | dicer 1, ribonuclease type III |
| DUX4L8 | double homeobox 4 like 8 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPS8L1 | EPS8-like 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM134B | family with sequence similarity 134, member B |
| FAM182A | family with sequence similarity 182, member A |
| FFAR2 | free fatty acid receptor 2 |
| FGF4 | fibroblast growth factor 4 |
| FLJ11292 | |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GDF10 | growth differentiation factor 10 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
| GPM6A | glycoprotein M6A |
| GPM6B | glycoprotein M6B |
| GPX7 | glutathione peroxidase 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HES2 | hes family bHLH transcription factor 2 |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
| IAPP | islet amyloid polypeptide |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGHM | immunoglobulin heavy constant mu |
| IL37 | interleukin 37 |
| ITGB4 | integrin, beta 4 |
| JAM2 | junctional adhesion molecule 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA0509 | uncharacterized LOC57242 |
| LOXL3 | lysyl oxidase-like 3 |
| LTC4S | leukotriene C4 synthase |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFAP5 | microfibrillar associated protein 5 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NEK11 | NIMA-related kinase 11 |
| NF1 | neurofibromin 1 |
| NRF1 | nuclear respiratory factor 1 |
| NRG1 | neuregulin 1 |
| PAEP | progestagen-associated endometrial protein |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PDE10A | phosphodiesterase 10A |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PML | promyelocytic leukemia |
| POM121 | POM121 transmembrane nucleoporin |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| REC8 | REC8 meiotic recombination protein |
| RERGL | RERG/RAS-like |
| RGS14 | regulator of G-protein signaling 14 |
| RPH3A | rabphilin 3A |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| SLC22A2 | solute carrier family 22 (organic cation transporter), member 2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMAD6 | SMAD family member 6 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| SULF1 | sulfatase 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TSGA10 | testis specific, 10 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF467 | zinc finger protein 467 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APH1B | APH1B gamma secretase subunit |
| ARRB2 | arrestin, beta 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CA9 | carbonic anhydrase IX |
| CEP131 | centrosomal protein 131kDa |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLDN15 | claudin 15 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ECE1 | endothelin converting enzyme 1 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ETNK2 | ethanolamine kinase 2 |
| ETV4 | ets variant 4 |
| FAT4 | FAT atypical cadherin 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPALPP1 | GPALPP motifs containing 1 |
| GPR176 | G protein-coupled receptor 176 |
| GPR3 | G protein-coupled receptor 3 |
| HELZ | helicase with zinc finger |
| HIST1H3A | histone cluster 1, H3a |
| HIST1H3I | histone cluster 1, H3i |
| IL15RA | interleukin 15 receptor, alpha |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0753 | KIAA0753 |
| KLF13 | Kruppel-like factor 13 |
| KRT8P12 | keratin 8 pseudogene 12 |
| MBTD1 | mbt domain containing 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MX1 | MX dynamin-like GTPase 1 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NPPB | natriuretic peptide B |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OLFM4 | olfactomedin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OSBP2 | oxysterol binding protein 2 |
| OSMR | oncostatin M receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PALM | paralemmin |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PODXL2 | podocalyxin-like 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTK6 | protein tyrosine kinase 6 |
| RBL1 | retinoblastoma-like 1 |
| RIMBP2 | RIMS binding protein 2 |
| RNF31 | ring finger protein 31 |
| RRAGB | Ras-related GTP binding B |
| RWDD2A | RWD domain containing 2A |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SFRP5 | secreted frizzled-related protein 5 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNTA1 | syntrophin, alpha 1 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| STK16 | serine/threonine kinase 16 |
| STXBP2 | syntaxin binding protein 2 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN1 | tectonic family member 1 |
| TFIP11 | tuftelin interacting protein 11 |
| THBS3 | thrombospondin 3 |
| TMEM212 | transmembrane protein 212 |
| TRIM45 | tripartite motif containing 45 |
| TSPAN2 | tetraspanin 2 |
| TUBA3D | tubulin, alpha 3d |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| WDR76 | WD repeat domain 76 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF227 | zinc finger protein 227 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF385D | zinc finger protein 385D |
| ZNF415 | zinc finger protein 415 |
| ZNF606 | zinc finger protein 606 |
