| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the tyloxapol-5672 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARD10 | caspase recruitment domain family, member 10 |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CDK13 | cyclin-dependent kinase 13 |
| CELP | carboxyl ester lipase pseudogene |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC2B | C-type lectin domain family 2, member B |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL10A1 | collagen, type X, alpha 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL1A1 | collagen, type I, alpha 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CTSF | cathepsin F |
| DBN1 | drebrin 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| FBN2 | fibrillin 2 |
| FPR2 | formyl peptide receptor 2 |
| FSTL4 | follistatin-like 4 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GPR157 | G protein-coupled receptor 157 |
| GPR21 | G protein-coupled receptor 21 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSN | gelsolin |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HR | hair growth associated |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| HYAL3 | hyaluronoglucosaminidase 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF25 | kinesin family member 25 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LMTK1 | lemur tail kinase 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MMP3 | matrix metallopeptidase 3 |
| MPPE1 | metallophosphoesterase 1 |
| MR1 | major histocompatibility complex, class I-related |
| MTMR7 | myotubularin related protein 7 |
| MYT1L | myelin transcription factor 1-like |
| MZF1 | myeloid zinc finger 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NID1 | nidogen 1 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PLAC1 | placenta-specific 1 |
| PMP2 | peripheral myelin protein 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RGS11 | regulator of G-protein signaling 11 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RPS3A | ribosomal protein S3A |
| S100A8 | S100 calcium binding protein A8 |
| SC5D | sterol-C5-desaturase |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLN | sarcolipin |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SYT11 | synaptotagmin XI |
| TAS2R4 | taste receptor, type 2, member 4 |
| TBC1D2B | TBC1 domain family, member 2B |
| TBXA2R | thromboxane A2 receptor |
| TCF4 | transcription factor 4 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX13A | testis expressed 13A |
| TLR1 | toll-like receptor 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRIM36 | tripartite motif containing 36 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| WDR78 | WD repeat domain 78 |
| ZNF222 | zinc finger protein 222 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTL8 | actin-like 8 |
| AEN | apoptosis enhancing nuclease |
| AFAP1 | actin filament associated protein 1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARRB1 | arrestin, beta 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCNO | cyclin O |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CLDN1 | claudin 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CXADR | coxsackie virus and adenovirus receptor |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DSPP | dentin sialophosphoprotein |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM186A | family with sequence similarity 186, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FILIP1L | filamin A interacting protein 1-like |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KLHL26 | kelch-like family member 26 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMA3 | laminin, alpha 3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK12 | mitogen-activated protein kinase 12 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICALL2 | MICAL-like 2 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NDRG4 | NDRG family member 4 |
| NECAP2 | NECAP endocytosis associated 2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PQLC1 | PQ loop repeat containing 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRPH | peripherin |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| S100A9 | S100 calcium binding protein A9 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TAOK1 | TAO kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TDRD3 | tudor domain containing 3 |
| TMEM180 | transmembrane protein 180 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM25 | tripartite motif containing 25 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBTD1 | ubiquitin domain containing 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF250 | zinc finger protein 250 |
| ZNF280D | zinc finger protein 280D |
| ZNF302 | zinc finger protein 302 |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF586 | zinc finger protein 586 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |
