| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the tyloxapol-6452 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADCY10 | adenylate cyclase 10 (soluble) |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AIM1L | absent in melanoma 1-like |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CARD14 | caspase recruitment domain family, member 14 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD6 | CD6 molecule |
| CDC25A | cell division cycle 25A |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CRLF2 | cytokine receptor-like factor 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 |
| CUL4B | cullin 4B |
| CYTH1 | cytohesin 1 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DFNB31 | deafness, autosomal recessive 31 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DMPK | dystrophia myotonica-protein kinase |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUOX2 | dual oxidase 2 |
| E2F5 | E2F transcription factor 5, p130-binding |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM106A | family with sequence similarity 106, member A |
| FFAR2 | free fatty acid receptor 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOXL1 | forkhead box L1 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GFER | growth factor, augmenter of liver regeneration |
| GLI2 | GLI family zinc finger 2 |
| GPR161 | G protein-coupled receptor 161 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HOXD9 | homeobox D9 |
| HR | hair growth associated |
| IBSP | integrin-binding sialoprotein |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| LEFTY1 | left-right determination factor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPT | microtubule-associated protein tau |
| MMP3 | matrix metallopeptidase 3 |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NF1 | neurofibromin 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OSMR | oncostatin M receptor |
| OVOL1 | ovo-like zinc finger 1 |
| PARVA | parvin, alpha |
| PARVB | parvin, beta |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM3 | PDZ and LIM domain 3 |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLAG1 | pleiomorphic adenoma gene 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PTRF | polymerase I and transcript release factor |
| PVR | poliovirus receptor |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX3 | runt-related transcription factor 3 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMAD3 | SMAD family member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNPH | syntaphilin |
| STMN1 | stathmin 1 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| TAPBPL | TAP binding protein-like |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TENM4 | teneurin transmembrane protein 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TOR4A | torsin family 4, member A |
| TRIM21 | tripartite motif containing 21 |
| TRIM36 | tripartite motif containing 36 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TUBA3C | tubulin, alpha 3c |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| USP19 | ubiquitin specific peptidase 19 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZNF510 | zinc finger protein 510 |
| ZNF675 | zinc finger protein 675 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMH | anti-Mullerian hormone |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CENPJ | centromere protein J |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CXXC4 | CXXC finger protein 4 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERCC5 | excision repair cross-complementation group 5 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FBXO31 | F-box protein 31 |
| FOSL1 | FOS-like antigen 1 |
| GID4 | GID complex subunit 4 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AM | histone cluster 1, H2am |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC10 | homeobox C10 |
| INO80D | INO80 complex subunit D |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIF13B | kinesin family member 13B |
| LONP2 | lon peptidase 2, peroxisomal |
| LRRC20 | leucine rich repeat containing 20 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL16 | methyltransferase like 16 |
| MYL5 | myosin, light chain 5, regulatory |
| NBAS | neuroblastoma amplified sequence |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHB8 | protocadherin beta 8 |
| PKN1 | protein kinase N1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PRPH | peripherin |
| PRR7 | proline rich 7 (synaptic) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PUS1 | pseudouridylate synthase 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RARS | arginyl-tRNA synthetase |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| REEP4 | receptor accessory protein 4 |
| RNF121 | ring finger protein 121 |
| RNF123 | ring finger protein 123 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMYD5 | SMYD family member 5 |
| SP140L | SP140 nuclear body protein-like |
| SPAG4 | sperm associated antigen 4 |
| SSBP3 | single stranded DNA binding protein 3 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYNC | syncoilin, intermediate filament protein |
| TESK1 | testis-specific kinase 1 |
| THYN1 | thymocyte nuclear protein 1 |
| TMEM8A | transmembrane protein 8A |
| TOM1 | target of myb1 (chicken) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBTD1 | ubiquitin domain containing 1 |
| VGF | VGF nerve growth factor inducible |
| VIM | vimentin |
| WDR4 | WD repeat domain 4 |
| ZNF16 | zinc finger protein 16 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF205 | zinc finger protein 205 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF428 | zinc finger protein 428 |
| ZNF446 | zinc finger protein 446 |
| ZNF692 | zinc finger protein 692 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
