tyr Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description tyrosinase|The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 7299)
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Genes

130 proteins co-occuring with the biological term tyr in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACTN1 actinin, alpha 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDOA aldolase A, fructose-bisphosphate
ALDOB aldolase B, fructose-bisphosphate
ANXA2 annexin A2
ARHGAP35 Rho GTPase activating protein 35
ARMC10 armadillo repeat containing 10
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
CAV1 caveolin 1, caveolae protein, 22kDa
CD3EAP CD3e molecule, epsilon associated protein
CD6 CD6 molecule
CDCP1 CUB domain containing protein 1
CDK1 cyclin-dependent kinase 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CREB1 cAMP responsive element binding protein 1
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCR4 chemokine (C-X-C motif) receptor 4
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
ELMO1 engulfment and cell motility 1
EPOR erythropoietin receptor
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO4 forkhead box O4
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB1 GRB2-associated binding protein 1
GHR growth hormone receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GRB7 growth factor receptor-bound protein 7
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HCLS1 hematopoietic cell-specific Lyn substrate 1
HIST1H3A histone cluster 1, H3a
HNF4A hepatocyte nuclear factor 4, alpha
HSF1 heat shock transcription factor 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL13RA1 interleukin 13 receptor, alpha 1
IL7R interleukin 7 receptor
INSR insulin receptor
IRS1 insulin receptor substrate 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUP junction plakoglobin
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT8 keratin 8, type II
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LEPR leptin receptor
LRP1 low density lipoprotein receptor-related protein 1
LRP6 low density lipoprotein receptor-related protein 6
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPL MPL proto-oncogene, thrombopoietin receptor
NBN nibrin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSF N-ethylmaleimide-sensitive factor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OCLN occludin
OPRM1 opioid receptor, mu 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCNA proliferating cell nuclear antigen
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PELP1 proline, glutamate and leucine rich protein 1
PFN1 profilin 1
PGAM1 phosphoglycerate mutase 1 (brain)
PHB prohibitin
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG1 phospholipase C, gamma 1
PLSCR1 phospholipid scramblase 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PTK2 protein tyrosine kinase 2
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PXN paxillin
PYGB phosphorylase, glycogen; brain
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RIPK2 receptor-interacting serine-threonine kinase 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS1 sorbin and SH3 domain containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
SYNJ2 synaptojanin 2
TP53 tumor protein p53
USF1 upstream transcription factor 1
WEE2 WEE1 homolog 2 (S. pombe)
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa