ubiquitin binding Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. (Gene Ontology, GO_0043130)
External Link http://amigo.geneontology.org/amigo/term/GO:0043130
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Genes

85 genes performing the ubiquitin binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ASCC2 activating signal cointegrator 1 complex subunit 2
BIRC2 baculoviral IAP repeat containing 2
BUB3 BUB3 mitotic checkpoint protein
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CXCR4 chemokine (C-X-C motif) receptor 4
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DNAAF10 dynein axonemal assembly factor 10
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
FAF1 Fas (TNFRSF6) associated factor 1
FAF2 Fas associated factor family member 2
FBXO7 F-box protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HSPB1 heat shock 27kDa protein 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains
KLF1 Kruppel-like factor 1 (erythroid)
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MARCHF7 membrane associated ring-CH-type finger 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MVB12A multivesicular body subunit 12A
MVB12B multivesicular body subunit 12B
N4BP1 NEDD4 binding protein 1
NBR1 neighbor of BRCA1 gene 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NSFL1C NSFL1 (p97) cofactor (p47)
NUP62 nucleoporin 62kDa
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTULINL OTU deubiquitinase with linear linkage specificity like
PLAA phospholipase A2-activating protein
PRKN parkin RBR E3 ubiquitin protein ligase
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RNASE7 ribonuclease, RNase A family, 7
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF185 ring finger protein 185
RNF19B ring finger protein 19B
RNF31 ring finger protein 31
RNFT1 ring finger protein, transmembrane 1
SHARPIN SHANK-associated RH domain interactor
SIRT2 sirtuin 2
SMAD3 SMAD family member 3
SPRTN SprT-like N-terminal domain
SQSTM1 sequestosome 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOLLIP toll interacting protein
TOM1 target of myb1 (chicken)
TOM1L1 target of myb1 (chicken)-like 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TRIM32 tripartite motif containing 32
TSG101 tumor susceptibility 101
UBAP1 ubiquitin associated protein 1
UBAP1L ubiquitin associated protein 1-like
UBE2A ubiquitin-conjugating enzyme E2A
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2N ubiquitin-conjugating enzyme E2N
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN1 UBX domain protein 1
UBXN10 UBX domain protein 10
UBXN11 UBX domain protein 11
UBXN2A UBX domain protein 2A
UBXN2B UBX domain protein 2B
UBXN7 UBX domain protein 7
UBXN8 UBX domain protein 8
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UEVLD UEV and lactate/malate dehyrogenase domains
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP21 ubiquitin specific peptidase 21
USP25 ubiquitin specific peptidase 25
USP33 ubiquitin specific peptidase 33
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USPL1 ubiquitin specific peptidase like 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
WDR48 WD repeat domain 48