umbilical Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

335 genes co-occuring with the biological term umbilical in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRBK1 adrenergic, beta, receptor kinase 1
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANXA2 annexin A2
ANXA5 annexin A5
ARG2 arginase 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AVP arginine vasopressin
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCAR1 breast cancer anti-estrogen resistance 1
BDNF brain-derived neurotrophic factor
BGN biglycan
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMX BMX non-receptor tyrosine kinase
BSG basigin (Ok blood group)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL16 chemokine (C-C motif) ligand 16
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCR3 chemokine (C-C motif) receptor 3
CD14 CD14 molecule
CD163 CD163 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFH complement factor H
CHEK1 checkpoint kinase 1
CHKA choline kinase alpha
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCN3 chloride channel, voltage-sensitive 3
CLDN5 claudin 5
CLU clusterin
CNR2 cannabinoid receptor 2 (macrophage)
CNTF ciliary neurotrophic factor
COL3A1 collagen, type III, alpha 1
COL6A2 collagen, type VI, alpha 2
CRHR2 corticotropin releasing hormone receptor 2
CSF3 colony stimulating factor 3 (granulocyte)
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSL cathepsin L
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CXORF40A chromosome X open reading frame 40A
CYBB cytochrome b-245, beta polypeptide
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DEFB4A defensin, beta 4A
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLL1 delta-like 1 (Drosophila)
DPP4 dipeptidyl-peptidase 4
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EFNB2 ephrin-B2
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
ELN elastin
ENO2 enolase 2 (gamma, neuronal)
EPO erythropoietin
ESR2 estrogen receptor 2 (ER beta)
ETV6 ets variant 6
F10 coagulation factor X
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAS Fas cell surface death receptor
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GDF15 growth differentiation factor 15
GHRL ghrelin/obestatin prepropeptide
GLUD1 glutamate dehydrogenase 1
GSK3B glycogen synthase kinase 3 beta
GSTK1 glutathione S-transferase kappa 1
HAS1 hyaluronan synthase 1
HAS2 hyaluronan synthase 2
HAS3 hyaluronan synthase 3
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSPG2 heparan sulfate proteoglycan 2
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL19 interleukin 19
IL2 interleukin 2
IL21 interleukin 21
IL33R interleukin 33 receptor
IL4 interleukin 4
IL6 interleukin 6
INHA inhibin, alpha
INHBB inhibin, beta B
INS insulin
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
JAG1 jagged 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KDR kinase insert domain receptor
KITLG KIT ligand
KLF2 Kruppel-like factor 2
KLK1 kallikrein 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LCN2 lipocalin 2
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCAM melanoma cell adhesion molecule
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR10A microRNA 10a
MIR124-1 microRNA 124-1
MIR143 microRNA 143
MIR145 microRNA 145
MIR146A microRNA 146a
MIR155 microRNA 155
MIR19A microRNA 19a
MIR19B1 microRNA 19b-1
MIR214 microRNA 214
MIR299 microRNA 299
MIR29A microRNA 29a
MIR361 microRNA 361
MIR9-1 microRNA 9-1
MIRLET7C microRNA let-7c
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MSI1 musashi RNA-binding protein 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NANOG Nanog homeobox
NCR3 natural cytotoxicity triggering receptor 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSTRIN nitric oxide synthase trafficking
NOTCH1 notch 1
NOTCH4 notch 4
NOX4 NADPH oxidase 4
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OSM oncostatin M
OXT oxytocin/neurophysin I prepropeptide
P4HB prolyl 4-hydroxylase, beta polypeptide
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PDGFD platelet derived growth factor D
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PGR progesterone receptor
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PITX2 paired-like homeodomain 2
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
PLG plasminogen
PNOC prepronociceptin
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PROM1 prominin 1
PTGFR prostaglandin F receptor (FP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPRC protein tyrosine phosphatase, receptor type, C
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RETN resistin
RHOA ras homolog family member A
RORA RAR-related orphan receptor A
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A13 S100 calcium binding protein A13
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEPT11 septin 11
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2B3 SH2B adaptor protein 3
SIRT1 sirtuin 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC38A2 solute carrier family 38, member 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SOCS3 suppressor of cytokine signaling 3
SOST sclerostin
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUSD6 sushi domain containing 6
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM1 transglutaminase 1
TGM2 transglutaminase 2
THBD thrombomodulin
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TSLP thymic stromal lymphopoietin
UCN urocortin
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UTS2 urotensin 2
VASH1 vasohibin 1
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
VTN vitronectin
VWF von Willebrand factor
XBP1 X-box binding protein 1
ZYX zyxin