upar Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Combining with the urokinase plasminogen activator to initiate a change in cell activity. (Gene Ontology, GO_0030377)
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Genes

102 genes co-occuring with the biological term upar in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA2 annexin A2
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC5 baculoviral IAP repeat containing 5
BSG basigin (Ok blood group)
CAMP cathelicidin antimicrobial peptide
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CD40LG CD40 ligand
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHEK2 checkpoint kinase 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTSB cathepsin B
CXCR4 chemokine (C-X-C motif) receptor 4
DOCK1 dedicator of cytokinesis 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
F12 coagulation factor XII (Hageman factor)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FADD Fas (TNFRSF6)-associated via death domain
FAP fibroblast activation protein, alpha
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FPR1 formyl peptide receptor 1
FPR3 formyl peptide receptor 3
HAX1 HCLS1 associated protein X-1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOXD10 homeobox D10
IGF2R insulin-like growth factor 2 receptor
IL33 interleukin 33
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK1 Janus kinase 1
JUN jun proto-oncogene
KDR kinase insert domain receptor
KLF4 Kruppel-like factor 4 (gut)
KLK4 kallikrein-related peptidase 4
KNG1 kininogen 1
LAMC2 laminin, gamma 2
LGALS3 lectin, galactoside-binding, soluble, 3
LRP1 low density lipoprotein receptor-related protein 1
LRP1B low density lipoprotein receptor-related protein 1B
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MBL2 mannose-binding lectin (protein C) 2, soluble
MIR10B microRNA 10b
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MYOCD myocardin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PGK1 phosphoglycerate kinase 1
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PRDX6 peroxiredoxin 6
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RHOB ras homolog family member B
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPX2 sushi-repeat containing protein, X-linked 2
ST2 suppression of tumorigenicity 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TERF2 telomeric repeat binding factor 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP1 TIMP metallopeptidase inhibitor 1
TJP2 tight junction protein 2
TP53 tumor protein p53
VCAM1 vascular cell adhesion molecule 1
VNN2 vanin 2
VTN vitronectin
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase