upper Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

203 genes co-occuring with the biological term upper in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACVR1 activin A receptor, type I
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AGER advanced glycosylation end product-specific receptor
AHR aryl hydrocarbon receptor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANXA2 annexin A2
ANXA3 annexin A3
APOA1 apolipoprotein A-I
AR androgen receptor
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATL1 atlastin GTPase 1
AURKA aurora kinase A
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BPIFA1 BPI fold containing family A, member 1
BRCA1 breast cancer 1, early onset
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CCK cholecystokinin
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD1A CD1a molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CKM creatine kinase, muscle
CLDN1 claudin 1
CLDN3 claudin 3
CLDN4 claudin 4
CLDN7 claudin 7
CP ceruloplasmin (ferroxidase)
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR5 chemokine (C-X-C motif) receptor 5
CYGB cytoglobin
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB1 defensin, beta 1
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLX6 distal-less homeobox 6
DRD2 dopamine receptor D2
DTD1 D-tyrosyl-tRNA deacylase 1
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F5 coagulation factor V (proaccelerin, labile factor)
FADD Fas (TNFRSF6)-associated via death domain
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FLG filaggrin
FMR1 fragile X mental retardation 1
FPR2 formyl peptide receptor 2
GHRL ghrelin/obestatin prepropeptide
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSDMA gasdermin A
GSDMB gasdermin B
GSDMC gasdermin C
GSDMD gasdermin D
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HBA1 hemoglobin, alpha 1
HELQ helicase, POLQ-like
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HMOX1 heme oxygenase 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFIH1 interferon induced with helicase C domain 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL17A interleukin 17A
IL1B interleukin 1, beta
IL20 interleukin 20
IL6 interleukin 6
IRGM immunity-related GTPase family, M
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITLN1 intelectin 1 (galactofuranose binding)
KISS1 KiSS-1 metastasis-suppressor
KLK13 kallikrein-related peptidase 13
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT31 keratin 31, type I
LEP leptin
LEPR leptin receptor
LIFR leukemia inhibitory factor receptor alpha
LOX lysyl oxidase
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MKI67 marker of proliferation Ki-67
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSX1 msh homeobox 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NRG1 neuregulin 1
NUMA1 nuclear mitotic apparatus protein 1
NUTM1 NUT midline carcinoma, family member 1
OCLN occludin
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OXTR oxytocin receptor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARVB parvin, beta
PAX8 paired box 8
PIGR polymeric immunoglobulin receptor
PITX1 paired-like homeodomain 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2F phospholipase A2, group IIF
PLCE1 phospholipase C, epsilon 1
PNPLA6 patatin-like phospholipase domain containing 6
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RB1 retinoblastoma 1
REEP1 receptor accessory protein 1
RNASE3 ribonuclease, RNase A family, 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RUNX2 runt-related transcription factor 2
RYR1 ryanodine receptor 1 (skeletal)
S100A4 S100 calcium binding protein A4
SATB1 SATB homeobox 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD4 SMAD family member 4
SNAI1 snail family zinc finger 1
SOD1 superoxide dismutase 1, soluble
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TAC1 tachykinin, precursor 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TAS2R38 taste receptor, type 2, member 38
TBX3 T-box 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGM3 transglutaminase 3
THAP1 THAP domain containing, apoptosis associated protein 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D3 TSC22 domain family, member 3
VASH1 vasohibin 1
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VIM vimentin
WNT7A wingless-type MMTV integration site family, member 7A
WWOX WW domain containing oxidoreductase
YY1 YY1 transcription factor